RAB1B, Member RAS Oncogene Family Proteine (RAB1B)

Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. Zusätzlich bieten wir Ihnen RAB1B, Member RAS Oncogene Family Antikörper (66) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RAB1B 81876 Q9H0U4
RAB1B 76308 Q9D1G1
RAB1B 100126191  
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Showing 10 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,331.68
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,331.68
Details
Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 15 bis 19 Tage
$407.00
Details
Hefe Macaca fascicularis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,489.67
Details
Human Cells Human Fc Tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$437.80
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 20 Days
$785.40
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,489.67
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,489.67
Details
Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$467.86
Details

RAB1B Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu RAB1B, Member RAS Oncogene Family (RAB1B) Interaktionspartnern

Human RAB1B, Member RAS Oncogene Family (RAB1B) Interaktionspartner

  1. Survival analysis indicates that patients with overexpression of Rab1B or MMP9 (zeige MMP9 Proteine) have significantly worse overall survival and progression-free survival, but better response to chemotherapy than those with low expression of proteins, and that Rab1B is an independent prognostic factor for colorectal cancer patients.

  2. In these Rab1B-depleted cells, ATG9A (zeige ATG9A Proteine) accumulated in intermediate membrane structures at autophagosome formation sites. These results indicate that Rab1B is involved in regulating the proper development of autophagosomes.

  3. Authors demonstrate that Rap1b (zeige RAP1B Proteine) expression is aberrantly increased in GC, resulting in the inhibition of autophagy and apoptosis of GC cells by the PI3K (zeige PIK3CA Proteine)/Akt (zeige AKT1 Proteine)/mTOR (zeige FRAP1 Proteine) pathway.

  4. RAB1B localization to the Golgi.

  5. RAB1B acts as a metastasis suppressor in triple-negative breast cancer by regulating the TGF-beta (zeige TGFB1 Proteine)/SMAD (zeige SMAD1 Proteine) signaling pathway and RAB1B may serve as a biomarker of prognosis and response to anti-tumor therapeutics for patients with triple-negative breast cancer.

  6. Our results show, for the first time, that changes in Rab1b levels modulate gene transcription and strongly suggest that a Rab1b increase is required to elicit a secretory response.

  7. The crystal structure of the Rab1b-LepB complex.

  8. results indicate that the cellular localization of MTMR6 (zeige MTMR6 Proteine) is regulated by Rab1B in the early secretory and autophagic pathways

  9. The detailed molecular reaction mechanism of a complex between human Rab (zeige HRB Proteine) and RabGAP at the highest possible spatiotemporal resolution and in atomic detail, is described.

  10. Rab1a/b and Rab43, are important for herpes simplex virus 1 virion assembly

Mouse (Murine) RAB1B, Member RAS Oncogene Family (RAB1B) Interaktionspartner

  1. Inhibition of PI3K or mTOR (zeige FRAP1 Proteine) reduced the level of Rap1B (zeige RAP1B Proteine), which acts downstream of Rheb (zeige RHEB Proteine) and mTOR (zeige FRAP1 Proteine). The ubiquitin E3 ligase Smurf2 (zeige SMURF2 Proteine) mediates the restriction of Rap1B (zeige RAP1B Proteine) by initiating its degradation.

RAB1B, Member RAS Oncogene Family (RAB1B) Protein Überblick

Protein Überblick

Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997

Genbezeichner und Symbole assoziert mit RAB1B

  • RAB1B, member RAS oncogene family (RAB1B)
  • RAB1B, member RAS oncogene family (Rab1b)
  • RAB1B, member RAS oncogene family, pseudogene 1 (Rab1b-ps1)
  • 1110011F09Rik Protein
  • Rab1b Protein
  • Rab1bl Protein

Bezeichner auf Proteinebene für RAB1B

RAB1B, member RAS oncogene family , ras-related protein Rab-1B , small GTP-binding protein , RAB1B-like, member RAS oncogene family

GENE ID SPEZIES
610762 Canis lupus familiaris
745036 Pan troglodytes
100174276 Pongo abelii
81876 Homo sapiens
76308 Mus musculus
100126191 Rattus norvegicus
540685 Bos taurus
100144502 Sus scrofa
361706 Rattus norvegicus
Ausgewählte Anbieter für RAB1B, Member RAS Oncogene Family Proteine (RAB1B)
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