anti-Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1) Antikörper

PCBD1 encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. Zusätzlich bieten wir Ihnen PCBD1 Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PCBD1 13180 P61458
PCBD1 5092 P61457
PCBD1 29700 P61459
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Top anti-PCBD1 Antikörper auf antikoerper-online.de

Showing 10 out of 51 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Pcbd1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Brain 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB PCBD1 Antibody (Center) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with PCBD1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of PCBD1 Antibody (Center) (ABIN653056) in mouse liver tissue lysates (35 µg/lane). PCBD1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with PCBD1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IC, IF, WB Immunofluorescent analysis of PCBD1 staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Western blot analysis of PCBD1 expression in SW620 (A), mouse kidney (B), mouse pancreas (C), rat liver (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details

PCBD1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)


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Human
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Rat (Rattus)


Weitere Antikörper gegen PCBD1 Interaktionspartner

Mouse (Murine) Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1) Interaktionspartner

  1. DCoH acts as a cofactor for HNF1 that stabilizes the dimeric HNF1 complex.

  2. HNF1alpha (zeige HNF1A Antikörper) binding kinetics may distinguish regulation by DCoH2 (zeige PCBD2 Antikörper), under thermodynamic control, from regulation by DCoH, under kinetic control

Human Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1) Interaktionspartner

  1. We provide the first genetic evidence that PCBD1 mutations can cause early-onset nonautoimmune diabetes with features similar to dominantly inherited HNF1A (zeige HNF1A Antikörper)-diabetes.

  2. Coactivator of the HNFB1 (HNF1 homeobox B (zeige HNF1B Antikörper))-mediated transcription is necessary for fine tuning ATPase Na+/K+ transporting gamma 1 polypeptide (FXYD2 (zeige FXYD2 Antikörper)) transcription in the distal convoluted tubule

  3. Pcbd1 is a moonlighting protein that has dehydratase activity in addition to functioning as a cofactor which regulates HNF1alpha (zeige HNF1A Antikörper).

  4. variants of the hepatocyte nuclear factor-1beta (HNF-1beta / TCF2 (zeige HNF1B Antikörper)) and the dimerization cofactor of HNF-1 (DcoH/PCBD) genes in relation to type 2 diabetes mellitus and beta-cell function

  5. Data reveal DCoH/HNF-1 alpha (zeige HNF1A Antikörper) expression and transcriptional activity in human epidermal melanocytes in vitro and in situ and identified tyrosinase (zeige TYR Antikörper), the key enzyme for pigmentation, as a new transcriptional target.

  6. Albumin (zeige ALB Antikörper) colocalized together with its transcription factor PCD/DCoH/HNF-1alpha (zeige HNF1A Antikörper) in suprabasal keratinocytes in human full-thickness skin sections and in keratinocytes cultured in serum-free medium.

  7. Properties of dehydratase/DCoHalpha are consistent with hypothesis that activity of this isozyme could account for relatively mild symptoms reported for patients with a defect in dehydratase/DCoH

PCBD1 Antigen-Profil

Protein Überblick

This gene encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1).

Genbezeichner und Symbole assoziert mit PCBD1

  • pterin-4a-carbinolamine dehydratase (Pcd) Antikörper
  • pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (pcbd1) Antikörper
  • pterin-4-alpha-carbinolamine dehydratase (Tb11.02.4890) Antikörper
  • pterin-4-alpha-carbinolamine dehydratase (pcbd) Antikörper
  • pterin-4-alpha-carbinolamine dehydratase (Fbal_2579) Antikörper
  • pterin-4-alpha-carbinolamine dehydratase (Ftrac_2004) Antikörper
  • pterin-4-alpha-carbinolamine dehydratase (Celal_2911) Antikörper
  • pterin-4-alpha-carbinolamine dehydratase (Isop_1133) Antikörper
  • pterin-4-alpha-carbinolamine dehydratase (Celly_0291) Antikörper
  • pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1 (Pcbd1) Antikörper
  • pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha L homeolog (pcbd1.L) Antikörper
  • pterin-4 alpha-carbinolamine dehydratase 1 (PCBD1) Antikörper
  • pterin-4 alpha-carbinolamine dehydratase 1 (Pcbd1) Antikörper
  • BcDNA:LP07248 Antikörper
  • CG1963 Antikörper
  • DCoH Antikörper
  • DDBDRAFT_0204977 Antikörper
  • DDBDRAFT_0305045 Antikörper
  • DDB_0204977 Antikörper
  • DDB_0305045 Antikörper
  • Dmel\\CG1963 Antikörper
  • PCBD Antikörper
  • pcd Antikörper
  • PHS Antikörper
  • TCF1 Antikörper
  • Xdcoh Antikörper
  • zgc:73389 Antikörper

Bezeichner auf Proteinebene für PCBD1

CG1963-PA , Pcd-PA , pterin-4-alpha-carbinolamine dehydratase , 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) , 4-alpha-hydroxy-tetrahydropterin dehydratase , PCD , PHS , dimerization cofactor of HNF1 , dimerization cofactor of hepatocyte nuclear factor 1-alpha , dimerization cofactor of hepatocyte nuclear factor-1-alpha , phenylalanine hydroxylase-stimulating protein , pterin carbinolamine dehydratase , DCoH , XDCoH , 6-pyruvoyl-tetrahydropterin synthase , cDcoH , pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) , dimerizing cofactor for HNF1 , pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1

GENE ID SPEZIES
43499 Drosophila melanogaster
393787 Danio rerio
496425 Xenopus (Silurana) tropicalis
3665797 Trypanosoma brucei brucei strain 927/4 GUTat10.1
8623790 Dictyostelium discoideum AX4
9771410 Ferrimonas balearica DSM 9799
10012150 Marivirga tractuosa DSM 4126
10145334 Cellulophaga algicola DSM 14237
10155246 Isosphaera pallida ATCC 43644
10262275 Cellulophaga lytica DSM 7489
13180 Mus musculus
397951 Xenopus laevis
395729 Gallus gallus
5092 Homo sapiens
530736 Bos taurus
29700 Rattus norvegicus
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