Protein Phosphatase 6, Catalytic Subunit Proteine (PPP6C)

PPP6C encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Zusätzlich bieten wir Ihnen Protein Phosphatase 6, Catalytic Subunit Antikörper (73) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PPP6C 5537 O00743
PPP6C 67857 Q9CQR6
Ratte PPP6C PPP6C 171121 Q64620
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Showing 3 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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PPP6C Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Protein Phosphatase 6, Catalytic Subunit (PPP6C) Interaktionspartnern

Human Protein Phosphatase 6, Catalytic Subunit (PPP6C) Interaktionspartner

  1. findings define the WHIP (zeige WRNIP1 Proteine)-TRIM14 (zeige TRIM14 Proteine)-PPP6C mitochondrial signalosome required for RIG-I (zeige DDX58 Proteine)-mediated innate antiviral immunity.

  2. Knockdown of Alpha4 preferentially impacts the expression of PP4c (zeige PPP4C Proteine) and PP6c compared to expression levels of PP2Ac (zeige PPP2CA Proteine).

  3. findings suggest that BRCA1 is a novel modulator of PP6 signalling via its interaction with ANKRD28.

  4. Data show 408 phosphopeptides on 272 proteins that increased and 298 phosphopeptides on 220 proteins that decreased in phosphorylation upon catalytic subunit of rotein phosphatase 6 (PP6c) depletion in mitotic cells.

  5. Protein phosphatase 6 ( (zeige NFKB1 Proteine)ppp6c), a ne (zeige MLXIP Proteine)gative regulator that restricts the G1 to S phase progression, is diminished in human psoriatic epidermis and is directly targeted by miR-31.

  6. PP6 is involved in a diverse set of biological pathways.

  7. These results suggest that human PP6 interacts with and positively regulates the activity of the influenza A virus RNA-dependent RNA polymerase.

  8. PP6C mutations have distinct functional and clinical consequences in melanoma, and confer sensitivity to Aurora A kinase (zeige AURKA Proteine) inhibitors.

  9. PP6c associates with E-cadherin (zeige CDH1 Proteine) in adherens junctions and is required to oppose casein kinase-1 (zeige CSNK1A1 Proteine) to maintain cell surface localization of E-cadherin (zeige CDH1 Proteine).

  10. Findings support the view that formation of micronuclei rather than chromosome instability alone explains how loss of PPP6C, and more generally mitotic spindle and centrosome defects, can act as drivers for genome instability in melanoma.

Mouse (Murine) Protein Phosphatase 6, Catalytic Subunit (PPP6C) Interaktionspartner

  1. the Ppp6c phosphatase domain is indispensable for mouse embryogenesis after implantation.

  2. findings uncover a hitherto unknown role for PP6 as an indispensable regulator of oocyte meiosis and female fertility.

  3. Data identify NF-kappaB (zeige NFKB1 Proteine)-induced miR (zeige MLXIP Proteine)-31 and its target, ppp6c, as critical factors for the hyperproliferation of epidermis in psoriasis.

  4. Ppp6c deficiency predisposes mice to skin carcinogenesis initiated by DMBA.

  5. Ppp6c deficiency underlies molecular events that drive outgrowth of initiated keratinocytes harboring UVB-induced mutated p53 (zeige TP53 Proteine)

  6. Our studies demonstrate that PP6 acts as a critical negative regulator of naive T cell homeostasis

  7. PP6 regulates the sensitivity of GBM cells to radiation, and suggest small molecules disrupting or inhibiting PP6 association with DNA-PK is a potential radiosensitizer for GBM.

  8. alpha4 expression differentially increased or decreased phosphorylation of endogenous phosphoproteins, consistent with opposing effects on PP2A (zeige PPP2R2B Proteine) and PP6 [PP6]

Protein Phosphatase 6, Catalytic Subunit (PPP6C) Protein Überblick

Protein Überblick

This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X.

Genbezeichner und Symbole assoziert mit PPP6C

  • Protein phosphatase V (PpV)
  • hypothetical LOC464731 (PPP6C)
  • protein phosphatase 6, catalytic subunit (PPP6C)
  • protein phosphatase V (ppp6c)
  • protein phosphatase 6, catalytic subunit (ppp6c)
  • protein phosphatase 6 catalytic subunit (ppp6C)
  • serine/threonine-protein phosphatase 6 catalytic subunit (Ppp6c)
  • protein phosphatase 6, catalytic subunit (Ppp6c)
  • 2310003C10Rik Protein
  • CG12217 Protein
  • DDBDRAFT_0168786 Protein
  • DDBDRAFT_0185210 Protein
  • DDB_0168786 Protein
  • DDB_0185210 Protein
  • Dmel\\CG12217 Protein
  • DmPpV-6A Protein
  • dPP6 Protein
  • MGC114734 Protein
  • pp6 Protein
  • PP6C Protein
  • ppp6c Protein
  • PPPV6A Protein
  • Ppv Protein
  • PPV 6A Protein
  • zgc:56227 Protein

Bezeichner auf Proteinebene für PPP6C

CG12217-PA , CG12217-PB , CG12217-PC , CG12217-PD , PpV-PA , PpV-PB , PpV-PC , PpV-PD , protein phosphatase V , protein phosphatase 6, catalytic subunit , serine/threonine-protein phosphatase 6 catalytic subunit , serine/threonine-protein phosphatase 6 catalytic subunit-like , serine/threonine protein phosphatase catalytic subunit , PP6C , PP-V

GENE ID SPEZIES
31582 Drosophila melanogaster
464731 Pan troglodytes
479534 Canis lupus familiaris
549864 Xenopus (Silurana) tropicalis
703658 Macaca mulatta
720872 Macaca mulatta
734439 Xenopus laevis
738446 Pan troglodytes
772354 Gallus gallus
8618444 Dictyostelium discoideum AX4
100015864 Monodelphis domestica
100070914 Equus caballus
100074888 Ornithorhynchus anatinus
100153256 Sus scrofa
100169448 Acyrthosiphon pisum
100479321 Ailuropoda melanoleuca
5537 Homo sapiens
67857 Mus musculus
511058 Bos taurus
171121 Rattus norvegicus
393980 Danio rerio
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