Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A Proteine (PPP1R14A)

The protein encoded by PPP1R14A belongs to the protein phosphatase 1 (PP1) inhibitor family. Zusätzlich bieten wir Ihnen Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A Antikörper (49) und Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PPP1R14A 94274 Q96A00
PPP1R14A 114004 Q99MC0
PPP1R14A 68458 Q91VC7
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Top Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A Proteine auf antikoerper-online.de

Showing 10 out of 13 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$407.00
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 12 bis 15 Tage
$378.24
Details
Escherichia coli (E. coli) Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$225.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$860.20
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Hefe Wildschwein His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,321.00
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,321.00
Details
Escherichia coli (E. coli) Human His tag   1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$4,009.50
Details

PPP1R14A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Rat (Rattus)

Mouse (Murine)

Weitere Proteine zu Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) Interaktionspartnern

Zebrafish Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) Interaktionspartner

  1. Hoxb1b is likely to directly regulate ppp1r14al expression in rhombomere 4. Furthermore, ppp1r14al is essential for establishment of the earliest hindbrain signaling-center in rhombomere 4 by regulating expression of fgf3 (zeige FGF3 Proteine).

Human Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) Interaktionspartner

  1. CPI-17 has a role in restoring skin homoeostasis in cutaneous field of cancerization lesions

  2. analysis of the interaction between plakoglobin (zeige JUP Proteine) and CPI-17, which is affected by the phosphorylation status of CPI-17 in human lung microvascular endothelial cells

  3. The N-terminal 21-residue tail domain of CPI-17 is necessary for nuclear localization. Phospho-mimetic Asp (zeige ASIP Proteine)-substitution of CPI-17 at Ser12 attenuates the nuclear import.

  4. The study characterized the CPI-17 promoter and identified binding sites for GATA-6 (zeige GATA6 Proteine) and nuclear factor kappa B (NF-kappaB (zeige NFKB1 Proteine)).

  5. a novel signaling cascade that links RhoA (zeige RHOA Proteine)-mediated calcium sensitivity to MEF2 (zeige MEF2A Proteine)-dependent myocardin expression in VSMCs through a mechanism involving p38 MAPK (zeige MAPK14 Proteine), PP1alpha (zeige PPP1CA Proteine), and CPI-17.

  6. RACK1 (zeige GNB2L1 Proteine) may play a role in PKC (zeige PRRT2 Proteine)/CPI-17 signaling pathway.

  7. cAMP/PKA regulates the endothelial barrier via inhibition of the contractile machinery, mainly by the activation of MLCP via inhibition of CPI-17 and RhoA (zeige RHOA Proteine)/Rock.

  8. mapped to chromosome 19q13.13-q13.2

  9. CPI-17 binds directly to protein kinase C and casein kinase I (zeige CSNK1D Proteine).

  10. importance of PKC (zeige PRRT2 Proteine)/CPI-17-mediated pathway in histamine-triggered cytoskeletal rearrangements leading to lung microvascular barrier compromise.

Mouse (Murine) Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) Interaktionspartner

  1. Enhanced vasorelaxation in early endotoxemia is mediated by redox signaling through PKG-1alpha but in later endotoxemia by myosin phosphatase isoform shifts enhancing sensitivity to NO/cGMP as well as smooth muscle atrophy.

  2. The study characterized the CPI-17 promoter and identified binding sites for GATA-6 (zeige GATA6 Proteine) and nuclear factor kappa B (NF-kappaB (zeige NFKB1 Proteine)).

  3. a novel signaling cascade that links RhoA (zeige RHOA Proteine)-mediated calcium sensitivity to MEF2 (zeige MEF2C Proteine)-dependent myocardin expression in VSMCs through a mechanism involving p38 MAPK (zeige MAPK14 Proteine), PP1alpha (zeige PPP1CA Proteine), and CPI-17.

  4. Data suggest that CPI-17 and both conventional and novel PKC isozymes contribute to the phasic and tonic contractile components of BALB/c colonic circular smooth muscle.

  5. Organ-specific mechanisms involving MYPT1 (zeige PPP1R12A Proteine), M-RIP, and CPI-17 are critical to regulating basal LC20 (zeige MYL9 Proteine) phosphorylation in gastrointestinal smooth muscles.

  6. calcium-independent phospholipase A2beta has a role in high glucose-induced activation of RhoA (zeige RHOA Proteine), Rho kinase (zeige ROCK2 Proteine), and CPI-17 in cultured vascular smooth muscle cells and vascular smooth muscle hypercontractility in diabetic animals

  7. distribution of mouse and rat PPP1R14A was more specific and different from that of humans

  8. concluded that actions downstream of cGMP/PKG (zeige PRKG1 Proteine) can reverse PKC-mediated phosphorylation of CPI-17 and Ca(2 (zeige CA2 Proteine)+) sensitization in smooth muscle

  9. findings suggest that CPI-17 was downregulated during intestinal inflammation and that TNF-alpha (zeige TNF Proteine) plays a central role in this process. Downregulation of CPI-17 may play a role in motility impairments in inflammation.

  10. CPI-17 expression is reversibly controlled in response to the phenotype transition of smooth muscle cells that restricts the signal to differentiated smooth muscle cells and particular cell types.

Pig (Porcine) Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) Interaktionspartner

  1. This study examined the protein expression and spatial-temporal distribution of PKCalpha (zeige PKCa Proteine) and CPI-17 in intact smooth muscle tissues.

Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Genbezeichner und Symbole assoziert mit PPP1R14A

  • protein phosphatase 1 regulatory inhibitor subunit 14A L homeolog (ppp1r14a.L)
  • protein phosphatase 1 regulatory inhibitor subunit 14A (ppp1r14a)
  • protein phosphatase 1, regulatory (inhibitor) subunit 14Aa (ppp1r14aa)
  • protein phosphatase 1 regulatory inhibitor subunit 14A (PPP1R14A)
  • protein phosphatase 1, regulatory (inhibitor) subunit 14A (PPP1R14A)
  • protein phosphatase 1, regulatory (inhibitor) subunit 14A (Ppp1r14a)
  • 1110001M11Rik Protein
  • CPI-17 Protein
  • Cpi17 Protein
  • im:7147597 Protein
  • MGC81874 Protein
  • PPP1INL Protein
  • PPP1R14A Protein
  • zgc:110700 Protein

Bezeichner auf Proteinebene für PPP1R14A

protein phosphatase 1, regulatory (inhibitor) subunit 14A , protein phosphatase 1 regulatory subunit 14A , 17 kDa PKC-potentiated inhibitory protein of PP1 , 17-KDa protein , 17-kDa PKC-potentiated inhibitory protein of PP1 , PKC-potentiated inhibitory protein of PP1 , protein kinase C-potentiated inhibitor protein of 17 kDa , CPI-17

GENE ID SPEZIES
447728 Xenopus laevis
493331 Xenopus (Silurana) tropicalis
550561 Danio rerio
612579 Canis lupus familiaris
615348 Bos taurus
641304 Ovis aries
747250 Pan troglodytes
94274 Homo sapiens
114004 Rattus norvegicus
68458 Mus musculus
397610 Sus scrofa
Ausgewählte Anbieter für Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A Proteine (PPP1R14A)
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