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anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) Antikörper

The protein encoded by PPP1CA is one of the three catalytic subunits of protein phosphatase 1 (PP1). Zusätzlich bieten wir Ihnen Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Proteine (14) und Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PPP1CA 19045 P62137
PPP1CA 5499 P62136
PPP1CA 24668 P62138
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Top anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Antikörper auf antikoerper-online.de

Showing 10 out of 126 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-PPP1CA Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate WB Suggested Anti-PPP1CA Antibody  Positive Control: Lane 1:441 µg HEK293 lysate Lane 2: 041 µg H1299 lysate Primary Antibody Dilution: 1:0000Secondary Antibody: Goat anti-rabbit-HRP Secondry  Antibody Dilution: 1:0000Submitted by: Jose Luis Rosa, Universitat de Barcelona 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Maus Unkonjugiert EIA, IHC (p), WB 0.1 mL Anmelden zum Anzeigen 8 bis 10 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using PP1-alpha (Phospho-Thr320) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using PP1-alpha (Ab-320) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PP1-alpha (Ab-320) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Maus Unkonjugiert IF, WB   0.1 mg Anmelden zum Anzeigen 8 bis 10 Tage
374,00 €
Details
Human Maus Unkonjugiert ELISA, WB Figure 1: Western blot analysis using PPP1A mouse mAb against Hela (1) and NIH/3T3 (2) cell lysate. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
399,32 €
Details
Human Maus Unkonjugiert ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Western blot analysis using PPP1CA mouse mAb against Hela (1), HepG2 (2), MCF-7 (3), Jurkat (4) and A549 (5) cell lysate. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
494,23 €
Details
Human Maus Unkonjugiert ICC, WB PPP1CA antibody at 1/1000 dilution, Lane1: HepG2 whole cell lysate 40ug/Lane, Lane2: Hela whole cell lysate 40ug/Lane, Predicted band size:37kDa, Observed band size:37kDa PPP1CA (N-terminus) antibody at 1/2000 dilution, Lane1: HepG2 whole cell lysate 40ug/Lane, Lane2: Hela whole cell lysate 40ug/Lane, Predicted band size: 37kDa, Observed band size: 37kDa 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
374,15 €
Details
Human Maus Unkonjugiert ICC, IHC, WB All lanes: PPP1CA antibody at 1/1000 dilution, Lane1: MCF7 Whole cell lysate 30ug/lane, Lane2: K562 Whole cell lysate 30ug/lane, Lane3: Hela Whole cell lysate 30ug/lane, Lane4: HEPG2 Whole cell lysate 30ug/lane, Lane5: Jurkat Whole cell lysate 30ug/lane, Predicted band size: 38kDa, Observed band size: 38kDa IHC of paraffin-embedded human breast cancer using anti- PPP1CA diluted 1/500-1/1000. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
374,15 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using PPP1A, antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with  (Red) at 1:2500. WB Image Sample(30 μg of whole cell lysate) A:293T B:A431, 12% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
Details

PPP1CA Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Antikörper

  1. Human Monoclonal PPP1CA Primary Antibody für ELISA, WB - ABIN969360 : Chen, Kesler, Paschal, Balk: Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1. in The Journal of biological chemistry 2009 (PubMed)
    Zeige alle 2 Referenzen für ABIN969360

  2. Human Monoclonal PPP1CA Primary Antibody für ELISA, WB - ABIN969359 : Luo, Peterson, Garcia, Coombs, Kofahl, Heinrich, Shabanowitz, Hunt, Yost, Virshup: Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. in The EMBO journal 2007 (PubMed)
    Zeige alle 2 Referenzen für ABIN969359

  3. Human Monoclonal PPP1CA Primary Antibody für IF, WB - ABIN1108708 : Barker, Jones, da Cruz e Silva, Spurr, Sheer, Cohen: Localization of the gene encoding a type I protein phosphatase catalytic subunit to human chromosome band 11q13. in Genomics 1990 (PubMed)
    Zeige alle 2 Referenzen für ABIN1108708

  4. Human Monoclonal PPP1CA Primary Antibody für EIA, IHC (p) - ABIN238369 : Cohen: Protein phosphatase 1--targeted in many directions. in Journal of cell science 2002 (PubMed)
    Zeige alle 2 Referenzen für ABIN238369

  5. Cow (Bovine) Polyclonal PPP1CA Primary Antibody für WB - ABIN2787782 : Lesage, Beullens, Pedelini, Garcia-Gimeno, Waelkens, Sanz, Bollen: A complex of catalytically inactive protein phosphatase-1 sandwiched between Sds22 and inhibitor-3. in Biochemistry 2007 (PubMed)

  6. Human Polyclonal PPP1CA Primary Antibody für IHC, ELISA - ABIN1532484 : Song, Khanna, Lu, Lavin: Cloning and characterization of a human protein phosphatase 1-encoding cDNA. in Gene 1993 (PubMed)

Weitere Antikörper gegen Protein Phosphatase 1, Catalytic Subunit, alpha Isoform Interaktionspartner

Mouse (Murine) Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) Interaktionspartner

  1. findings demonstrate a novel regulatory circuit in which STING and TBK1 (zeige TBK1 Antikörper) reciprocally regulate each other to enable efficient antiviral signaling activation, and PPM1A (zeige PPM1A Antikörper) dephosphorylates STING and TBK1 (zeige TBK1 Antikörper)

  2. the studies presented here position PPM1A (zeige PPM1A Antikörper) as a new player in the wound healing-inflammation-angiogenesis axis in mouse, reveal its crucial role in homeostasis on injury, and highlight its potential as a therapeutic mediator in pathologic conditions

  3. Ang (zeige ANG Antikörper) IV functions via regulating the activity of PP1 (zeige PPP1CC Antikörper)

  4. a nuclear envelope-localized mechanism of inactivating TGF-beta (zeige TGFB1 Antikörper) signaling in which MAN1 (zeige LEMD3 Antikörper) competes with transcription factors for binding to Smad2 (zeige SMAD2 Antikörper) and Smad3 (zeige SMAD3 Antikörper) and facilitates their dephosphorylation by PPM1A (zeige PPM1A Antikörper).

  5. Although a non-myristoylated mutation (G2A (zeige GPR132 Antikörper)) of PPM1A (zeige PPM1A Antikörper) and PPM1B (zeige PPM1B Antikörper) prevented membrane association, this relocalization did not likely cause the decreased activity towards AMPKalpha (zeige GRK4 Antikörper).

  6. we found that PPM1A (zeige PPM1A Antikörper) mRNA is synthesized at the beginning of the maturation process and remains elevated in the mature oocytes, promoting the accumulation of PPM1A (zeige PPM1A Antikörper) protein

  7. Cell surface expression of the major amyloid-beta peptide (Abeta (zeige APP Antikörper))-degrading enzyme, neprilysin (zeige MME Antikörper), depends on phosphorylation by mitogen-activated protein kinase (zeige MAPK1 Antikörper)/extracellular signal-regulated kinase kinase (MEK (zeige MDK Antikörper)) and dephosphorylation by protein phosphatase 1a (zeige PPM1A Antikörper).

  8. analysis of selective regulation of NR2B (zeige GRIN2B Antikörper) by protein phosphatase-1 (zeige PPP1CB Antikörper) for the control of the NMDA receptor in neuroprotection

  9. Protein phosphatase PPM1A (zeige PPM1A Antikörper) regulates the nuclear export of Smad2 (zeige SMAD2 Antikörper)/3 through targeting nuclear exporter RanBP3 (zeige RANBP3 Antikörper).

  10. Ppm1a (zeige PPM1A Antikörper), through suppressing Smad2 (zeige SMAD2 Antikörper) signaling, plays a critical role in re-epithelialization during wound healing

Human Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) Interaktionspartner

  1. These results indicate that PP1 (zeige PPA1 Antikörper) is recruited to the extracellular calcium-dependent E-cadherin (zeige CDH1 Antikörper)-catenin-PIP5K1a (zeige PIP5K1A Antikörper) complex in the plasma membrane to activate PIP5K1a (zeige PIP5K1A Antikörper), which is required for PLC (zeige HSPG2 Antikörper)-g1 activation leading to keratinocyte differentiation.

  2. Data suggest that targeting protein phosphatase 1 catalytic subunit (zeige PPP1CB Antikörper) (PP1alpha) or the androgen receptor AR (zeige AR Antikörper)-PP1alpha interaction may be effective in castration-resistant prostate cancer (CRPC).

  3. Both PP-1 (zeige PPA1 Antikörper) and PP-2A are directly involved in regulating eye development, and are aberrantly expressed in cataract and glaucoma patients. (Review)

  4. Data suggest that activation of TAZ (tafazzin (zeige TAZ Antikörper)) inhibits adipogenesis in mesenchymal stem cells; interaction of TAZ (zeige TAZ Antikörper) and protein phosphatases (PP1A, PP2A (zeige PPP2R4 Antikörper)) up-regulates dephosphorylation and transport of TAZ (zeige TAZ Antikörper) to cell nucleus.

  5. ATG16L1 (zeige ATG16L1 Antikörper) as a bona fide physiological CSNK2 and PPP1 substrate, which reveals a novel molecular link from CSNK2 to activation of the autophagy-specific ATG12 (zeige ATG12 Antikörper)-ATG5 (zeige ATG5 Antikörper)-ATG16L1 (zeige ATG16L1 Antikörper) complex and autophagy induction

  6. PARD3 (zeige PARD3 Antikörper) promotes interaction between PP1A and LATS1 (zeige LATS1 Antikörper) to induce LATS1 (zeige LATS1 Antikörper) dephosphorylation and inactivation,leading to dephosphorylation and activation of TAZ (zeige TAZ Antikörper)

  7. activation of the Nherf1 (zeige SLC9A3R1 Antikörper)-PP1alpha-TAZ (zeige TAZ Antikörper) pathway in osteoblasts is targeted by histone deacetylase (zeige HDAC1 Antikörper) inhibitors

  8. findings demonstrate a novel regulatory circuit in which STING and TBK1 (zeige TBK1 Antikörper) reciprocally regulate each other to enable efficient antiviral signaling activation, and PPM1A (zeige PPM1A Antikörper) dephosphorylates STING and TBK1 (zeige TBK1 Antikörper)

  9. Protein phosphatase 1 (zeige PPP1CB Antikörper) (PP1 (zeige PPA1 Antikörper)) activity is critical for radiosensitization in non-small cell lung cancer cells and PP1 (zeige PPA1 Antikörper) activators can serve as promising radiosensitizers to improve therapeutic efficacy.

  10. The TGF-beta (zeige TGFB1 Antikörper)/Smad (zeige SMAD1 Antikörper) signaling system decreases its activity through strong negative regulation. We provide evidence for a new negative feedback loop through PPM1A (zeige PPM1A Antikörper) upregulation.

Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Genbezeichner und Symbole assoziert mit PPP1CA

  • protein phosphatase 1, catalytic subunit, alpha isozyme (ppp1ca) Antikörper
  • protein phosphatase 1, catalytic subunit, alpha isozyme (PPP1CA) Antikörper
  • protein phosphatase 1, catalytic subunit, alpha isoform (Ppp1ca) Antikörper
  • protein phosphatase 1, catalytic subunit, alpha isoform a (ppp1caa) Antikörper
  • protein phosphatase 1, catalytic subunit, alpha isozyme (Ppp1ca) Antikörper
  • protein phosphatase 1, catalytic subunit, beta isozyme (Ppp1cb) Antikörper
  • protein phosphatase 1A, magnesium dependent, alpha isoform (Ppm1a) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent, 1A (PPM1A) Antikörper
  • 2310003C21Rik Antikörper
  • 2900017D14Rik Antikörper
  • AI427932 Antikörper
  • AU017636 Antikörper
  • dism2 Antikörper
  • MMPa-2 Antikörper
  • MPPa-1 Antikörper
  • PP-1A Antikörper
  • PP1A Antikörper
  • PP1alpha Antikörper
  • PP2C-ALPHA Antikörper
  • PP2CA Antikörper
  • PP2Calpha Antikörper
  • PPP1A Antikörper
  • Ppp1c Antikörper
  • wu:fc04c08 Antikörper
  • wu:fc09b07 Antikörper
  • wu:fc30g11 Antikörper
  • wu:fe05h08 Antikörper
  • zgc:85729 Antikörper

Bezeichner auf Proteinebene für PPP1CA

Protein phosphatase type 1 alpha, catalytic subunit , protein phosphatase 1, catalytic subunit, alpha isoform , PP-1A , serine/threonine-protein phosphatase PP1-alpha catalytic subunit , ppp1ca , protein phosphatase 1, catalytic subunit, alpha , serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit , protein phosphatase-1d , PP-1B , protein phosphatase 1, catalytic subunit, beta isoform , protein phosphatase-1a , serine/threonine-protein phosphatase PP1-beta catalytic subunit , Mpp alpha , PP2C-alpha , protein phosphatase 1A , protein phosphatase 2C isoform alpha , protein phosphatase IA , protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform , IA , protein phosphatase 2C alpha

GENE ID SPEZIES
379914 Xenopus laevis
745709 Pan troglodytes
100059233 Equus caballus
100145598 Xenopus (Silurana) tropicalis
19045 Mus musculus
407980 Danio rerio
5499 Homo sapiens
24668 Rattus norvegicus
516175 Bos taurus
403609 Canis lupus familiaris
100009298 Oryctolagus cuniculus
25594 Rattus norvegicus
19042 Mus musculus
5494 Homo sapiens
281994 Bos taurus
100009431 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) Antikörper
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