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Protein Geranylgeranyltransferase Type I, beta Subunit Proteine (PGGT1B)

Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). Zusätzlich bieten wir Ihnen Protein Geranylgeranyltransferase Type I, beta Subunit Antikörper (44) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PGGT1B 5229 P53609
PGGT1B 81746 P53610
PGGT1B 225467 Q8BUY9
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Showing 5 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.891,43 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.891,43 €
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PGGT1B Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Rat (Rattus)

Mouse (Murine)

Weitere Proteine zu Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B) Interaktionspartnern

Human Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B) Interaktionspartner

  1. our study showed, for the first time, that HIF-1alpha (zeige HIF1A Proteine) was regulated by protein prenylation transferase GGTI and mediated the effect of GGTI on glioma cell migration and invasion

  2. RNAi knockdown of GGTase-Ibeta inhibited invasion, disrupted F-actin organization and decreased the level of cofilin (zeige CFL1 Proteine) in PC-3 (zeige PCSK1 Proteine) cells.

  3. results suggest that geranylgeranylation of RhoA (zeige RHOA Proteine) is critical for cancer cell invasion

Mouse (Murine) Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B) Interaktionspartner

  1. Targeting GGTase-I activates RHOA (zeige RHOA Proteine) and leads to increased macrophage reverse cholesterol transport and reduced atherosclerosis development despite a significant increase in inflammation.

  2. Both Fntb and Pggt1b are required for the homeostasis of skin keratinocytes.

Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B) Protein Überblick

Protein Überblick

Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994

Genbezeichner und Symbole assoziert mit PGGT1B

  • protein geranylgeranyltransferase type I, beta subunit (PGGT1B)
  • protein geranylgeranyltransferase type I, beta subunit (pggt1b)
  • protein geranylgeranyltransferase type I, beta subunit (Pggt1b)
  • 2010207C17Rik Protein
  • 2610100E13 Protein
  • AI451237 Protein
  • AI551093 Protein
  • BGG1 Protein
  • BGGI Protein
  • GGT1 Protein
  • GGTI Protein
  • MGC115505 Protein

Bezeichner auf Proteinebene für PGGT1B

protein geranylgeranyltransferase type I, beta subunit , GGTase-I-beta , geranylgeranyl transferase type I subunit beta , geranylgeranyl transferase type-1 subunit beta , geranylgeranyltransferase type I beta subunit , type I protein geranyl-geranyltransferase subunit beta , geranylgeranyltransferase type 1 beta , geranylgeranyltransferase type I (GGTase-I)

GENE ID SPEZIES
770633 Gallus gallus
481440 Canis lupus familiaris
734580 Xenopus laevis
5229 Homo sapiens
81746 Rattus norvegicus
225467 Mus musculus
509322 Bos taurus
Ausgewählte Anbieter für Protein Geranylgeranyltransferase Type I, beta Subunit Proteine (PGGT1B)
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