anti-Protein C Receptor, Endothelial (PROCR) Antikörper

The protein encoded by PROCR is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. Zusätzlich bieten wir Ihnen PROCR Kits (57) und PROCR Proteine (34) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PROCR 10544 Q9UNN8
PROCR 362248 Q4V8I1
PROCR 19124 Q64695
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Top anti-PROCR Antikörper auf antikoerper-online.de

Showing 10 out of 173 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of CD201 antibody (Center) (ABIN389416) in T47D cell line lysates (35 µg/lane). CD201 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma with CD201 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Ziege Unkonjugiert CyTOF, FACS, IHC, WB EPCR in Human Liver. EPCR was detected in immersion fixed paraffin-embedded sections of human liver using 1.7 ug/mL Goat Anti-Human EPCR Antigen Affinity-purified Polyclonal Antibody. Detection of Human EPCR by Western Blot. Western blot shows lysates of human skin tissue, human placenta tissue, and HUVEC human umbilical vein endothelial cells. PVDF membrane was probed with 0.25 ug/mL of Goat Anti-Human EPCR Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
355,00 €
Details
Maus Ziege Unkonjugiert CyTOF, FACS, ICC, IP, WB Detection of EPCR in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Goat Anti-Mouse EPCR Antigen Affinity-purified Polyclonal Antibody. EPCR in bEnd.3 Mouse Cell Line. EPCR was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Goat Anti-Mouse EPCR Antigen Affinity-purified Polyclonal Antibody. Specific staining was localized to cytoplasm. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
375,00 €
Details
Human Ziege Biotin FACS, IHC, WB EPCR in Human Liver. EPCR was detected in immersion fixed paraffin-embedded sections of human liver array using Goat Anti-Human EPCR Biotinylated Antigen Affinity-purified Polyclonal Antibody. Lower panel shows a lack of labeling if primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents. EPCR in Human Liver. EPCR was detected in immersion fixed paraffin-embedded sections of human liver array using Goat Anti-Human EPCR Biotinylated Antigen Affinity-purified Polyclonal Antibody  at 15 ug/mL overnight at 4 ᄚC. Tissue was stained using the Anti-Goat HRP-DAB Cell & 50 μg Anmelden zum Anzeigen 3 bis 4 Tage
380,00 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC (p), WB Western Blot (WB) analysis of Rat barin lysis using CD201 antibody. 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB   200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
Details
Human Kaninchen Unkonjugiert WB Western Blot: EPCR Antibody [NBP2-21578] - A. 30 ug HeLa whole cell lysate/extract12 % SDS-PAGEEPCR antibody dilution: 1:1000. Western Blot: EPCR Antibody [NBP2-21578] - Sample (30 ug of whole cell lysate) A: JC B: BCL-1 12% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of EPCR/CD201 expression in A549 whole cell lysates (lane 1). EPCR/CD201 at 46KD, 52KD was detected using rabbit anti- EPCR/CD201 Antigen Affinity purified polyclonal antibody at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Human Ratte Unkonjugiert BP, FACS, MA, Neut   0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
361,00 €
Details

PROCR Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-PROCR Antikörper

  1. Human Monoclonal PROCR Primary Antibody für IF, IHC (p) - ABIN564600 : Lee, Ku, Bae: Emodin-6-O-?-D-glucoside down-regulates endothelial protein C receptor shedding. in Archives of pharmacal research 2013 (PubMed)
    Show all 6 Pubmed References

  2. Human Monoclonal PROCR Primary Antibody für Func, FACS - ABIN2192008 : Ye, Fukudome, Tsuneyoshi, Satoh, Tokunaga, Sugawara, Mizokami, Kimoto: The endothelial cell protein C receptor (EPCR) functions as a primary receptor for protein C activation on endothelial cells in arteries, veins, and capillaries. in Biochemical and biophysical research communications 1999 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal PROCR Primary Antibody für Func, FACS - ABIN2192007 : Dömötör, Benzakour, Griffin, Yule, Fukudome, Zlokovic: Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1. in Blood 2003 (PubMed)
    Show all 5 Pubmed References

  4. Human Polyclonal PROCR Primary Antibody für CyTOF, FACS - ABIN4899324 : Ducros, Berthaut, Mirshahi, Faussat, Soria, Agarwal, Mirshahi: Aldosterone modifies hemostasis via upregulation of the protein-C receptor in human vascular endothelium. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 5 Pubmed References

  5. Mouse (Murine) Polyclonal PROCR Primary Antibody für CyTOF, FACS - ABIN4899294 : Greineder, Chacko, Zaytsev, Zern, Carnemolla, Hood, Han, Ding, Esmon, Muzykantov: Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor. in PLoS ONE 2013 (PubMed)
    Show all 5 Pubmed References

  6. Human Monoclonal PROCR Primary Antibody für FACS - ABIN2689080 : Biguzzi, Merati, Liaw, Bucciarelli, Oganesyan, Qu, Gu, Fetiveau, Esmon, Mannucci, Faioni: A 23bp insertion in the endothelial protein C receptor (EPCR) gene impairs EPCR function. in Thrombosis and haemostasis 2001 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal PROCR Primary Antibody für WB - ABIN4270023 : Gera, Shavit-Stein, Bushi, Harnof, Shimon, Weiss, Golderman, Dori, Maggio, Finegold, Chapman: Thrombin and protein C pathway in peripheral nerve Schwann cells. in Neuroscience 2016 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal PROCR Primary Antibody für FACS, IHC - ABIN4899323 : Gunawardana, Kuk, Smith, Batruch, Soosaipillai, Diamandis: Comprehensive analysis of conditioned media from ovarian cancer cell lines identifies novel candidate markers of epithelial ovarian cancer. in Journal of proteome research 2009 (PubMed)

  9. Human Monoclonal PROCR Primary Antibody für BP, FACS - ABIN269970 : Schut, Kirschbaum, Adelmeijer, de Groot, Lisman: In vitro uptake of recombinant factor VIIa by megakaryocytes with subsequent production of platelets containing functionally active drug. in British journal of haematology 2016 (PubMed)

Weitere Antikörper gegen PROCR Interaktionspartner

Human Protein C Receptor, Endothelial (PROCR) Interaktionspartner

  1. EPCR occupancy recruits G-protein coupled receptor kinase 5 (zeige GRK5 Antikörper), thereby inducing beta-arrestin-2 (zeige ARRB2 Antikörper) biased PAR1 (zeige MARK2 Antikörper) signaling by both APC (zeige APC Antikörper) and thrombin (zeige F2 Antikörper). In

  2. EPCR polymorphisms may be associated with increased risk of sepsis, but this has no effect on the release of soluble EPCR in patients with sepsis.

  3. Elevated endothelium-related mediators (vWF (zeige VWF Antikörper), E-selectin (zeige SELE Antikörper) and EPCR) appear to participate in the development of pancreatic necrosis and may be a potential indicator of overall prognosis.

  4. The results showed that AS-IV could significantly inhibit PMA-induced EPCR shedding.

  5. CORM-2 protects human umbilical vein endothelial cells from lipopolysaccharide-induced injury, by way of suppressing NF-kappaB (zeige NFKB1 Antikörper) activity, which downregulates TM and EPCR mRNAs. It also decreases MMP-2 (zeige MMP2 Antikörper) expression and prevents the shedding of TM and EPCR from the surface of endothelial cells, so as to preserve their protective effect.

  6. This study shows that ICAM-1 (zeige ICAM1 Antikörper) is a coreceptor for a subset of EPCR-binding Plasmodium falciparum parasites and provides the first evidence of how EPCR and ICAM-1 (zeige ICAM1 Antikörper) interact to mediate parasite binding to both resting and TNF-alpha (zeige TNF Antikörper)-activated primary brain and lung endothelial cells.

  7. This study demonstrates that impaired EPCR function can be detected by thrombin (zeige F2 Antikörper) generation and clot (zeige TXNDC17 Antikörper) lysis assays on cells expressing thrombomodulin (zeige THBD Antikörper) and EPCR. Deficiency in EPCR has procoagulant effects that lead to a delay in clot (zeige TXNDC17 Antikörper) lysis.

  8. Observations that binding of P. falciparum erythrocyte membrane protein 1 to EPCR results in an acquired functional protein C (zeige PROC Antikörper) system deficiency support the new paradigm that EPCR plays a central role in the pathogenesis of severe malaria. [review]

  9. data suggest that either the lack of the protective EPCR 4678C allele or the presence of EPCR 4600G allele may be associated with earlier development of thrombosis.

  10. These data suggest that 6936A/G polymorphism is a risk factor for deep venous thrombosis and is associated with elevated plasma levels of soluble EPCR, while 4678G/C polymorphism plays a role in protection against deep venous thrombosis.

Mouse (Murine) Protein C Receptor, Endothelial (PROCR) Interaktionspartner

  1. PROCR thus does not globally inhibit Th17 responses but could be targeted to selectively inhibit proinflammatory Th17 cells.

  2. Thrombin (zeige F2 Antikörper)-PAR1 (zeige F2R Antikörper) signaling, via nitric oxide and EPCR, promotes hematopoietic stem cell (HSC (zeige FUT1 Antikörper)) mobilization. aPC (zeige APC Antikörper)-EPCR-PAR1 (zeige F2R Antikörper) signaling promotes HSC (zeige FUT1 Antikörper) retention in bone marrow.

  3. impaired EPCR/protein C (zeige PROC Antikörper)-binding interactions not only result in procoagulant and proinflammatory effects, but also impact hematopoiesis

  4. sPLA2 (zeige PLA2G2A Antikörper)-V plays a thrombogenic role by impairing the ability of EPCR to promote protein C (zeige PROC Antikörper) activation.

  5. HSCs appear to maintain expression of CD201 after hematopoietic injury when Kit expression is downregulated.

  6. The protein C (zeige PROC Antikörper) receptor (ProcR; EPCR) was required for the normal in vivo and in vitro induction of lipopolysaccharide (LPS (zeige TLR4 Antikörper))-regulated gene expression.

  7. Data indicate that endothelial protein C receptor (EPCR) binding enhances FVIIa hemostatic activity in vivo.

  8. protein C (zeige PROC Antikörper) receptor (Procr), a novel Wnt (zeige WNT2 Antikörper) target in the mammary gland, marks a unique population of multipotent mouse mammary stem cells

  9. FVIIa binding to EPCR leads to a barrier protective effect in vivo

  10. Piperlonguminine might have potential as an anti-sEPCR shedding reagent against sepsis-mediated EPCR shedding.

PROCR Antigen-Profil

Protein Überblick

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.

Genbezeichner und Symbole assoziert mit PROCR

  • protein C receptor, endothelial (EPCR) (PROCR) Antikörper
  • protein C receptor, endothelial (PROCR) Antikörper
  • protein C receptor, endothelial (Procr) Antikörper
  • AI325044 Antikörper
  • Ccca Antikörper
  • Ccd41 Antikörper
  • Epcr Antikörper
  • PROCR Antikörper

Bezeichner auf Proteinebene für PROCR

protein C receptor, endothelial (EPCR) , APC receptor , CD201 antigen , activated protein C receptor , cell cycle, centrosome-associated protein , centrocyclin , endothelial protein C receptor , endothelial cell protein C receptor , CD antigen CD201 , centrosomal protein CCD41 , endothelial cell protein C/activated protein C

GENE ID SPEZIES
458198 Pan troglodytes
10544 Homo sapiens
362248 Rattus norvegicus
19124 Mus musculus
100731547 Cavia porcellus
654289 Sus scrofa
282005 Bos taurus
485848 Canis lupus familiaris
424867 Gallus gallus
101115814 Ovis aries
Ausgewählte Anbieter für anti-PROCR (PROCR) Antikörper
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