anti-Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) Antikörper

PTGIS encodes a member of the cytochrome P450 superfamily of enzymes. Zusätzlich bieten wir Ihnen Prostaglandin I2 (Prostacyclin) Synthase Kits (26) und Prostaglandin I2 (Prostacyclin) Synthase Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PTGIS 19223 O35074
PTGIS 25527 Q62969
PTGIS 5740 Q16647
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Top anti-Prostaglandin I2 (Prostacyclin) Synthase Antikörper auf antikoerper-online.de

Showing 10 out of 67 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA, WB Formalin-fixed and paraffin-embedded human prostate carcinoma reacted withPTGIS Antibody (C-term) followed which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of PTGIS Antibody (C-term) Cat.-No AP17980PU-N in CEM cell line lysates (35ug/lane). CYP8A1 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
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Human Maus Unkonjugiert ELISA, WB PTGIS polyclonal antibody (A01), Lot # 050921JC01 Western Blot analysis of PTGIS expression in NIH/3T3 . Western Blot detection against Immunogen (38.21 KDa) . 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
241,60 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of CYP8A1 Antibody (C-term) (ABIN652421) in CEM cell line lysates (35 µg/lane). CYP8A1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with PAX3 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-CYP8A1 Antibody (N-term) (ABIN392532) in mouse lung tissue lysates (35 µg/lane). CYP8A1(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP8A1 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Fledermaus Kaninchen Unkonjugiert IHC, WB 0.05 mg Anmelden zum Anzeigen 6 bis 8 Tage
505,48 €
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Human Kaninchen Unkonjugiert IF (p), IHC (p), WB B16 Cell lysates probed with CYP8A1/PTGIS Polyclonal Antibody, unconjugated  at 1:300 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Details

PTGIS Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Prostaglandin I2 (Prostacyclin) Synthase Antikörper

  1. Human Polyclonal PTGIS Primary Antibody für ELISA, WB - ABIN562513 : Gurgul-Convey, Hanzelka, Lenzen: Mechanism of prostacyclin-induced potentiation of glucose-induced insulin secretion. in Endocrinology 2012 (PubMed)

Weitere Antikörper gegen Prostaglandin I2 (Prostacyclin) Synthase Interaktionspartner

Cow (Bovine) Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) Interaktionspartner

Mouse (Murine) Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) Interaktionspartner

  1. Prostacyclin synthase and prostaglandin E synthase (zeige PTGES Antikörper)-1 cooperatively exacerbate inflammatory reactions but have opposing effects on carcinogenesis.

  2. Cyclooxygenase-2 (zeige PTGS2 Antikörper)-derived prostacyclin regulates arterial thrombus formation by suppressing tissue factor (zeige F3 Antikörper) in a sirtuin-1 (zeige SIRT1 Antikörper)-dependent-manner.

  3. CD40 ligand (zeige CD40LG Antikörper) might contribute to the initiation and progression of atherosclerosis by increasing activity of prostacyclin synthase.

  4. Sepiapterin not only reversed the effects of high glucose on both angiotensin II-induced relaxation and PGI(2 (zeige PTGIR Antikörper)) release but also abolished high-glucose-enhanced PGIS nitration.

  5. Alpha(2)-adrenoreceptor activation is required for coupling heart rate to central inspiratory drive during acute hypoxia, and PGI(2 (zeige PTGIR Antikörper)) is required to enhance the inhibition of sympathoactivation.

  6. The results provide strong evidence that the protective effects of COX-2 (zeige COX2 Antikörper) within the liver are mediated through the production of PGE (zeige LIPF Antikörper)(2) and PGI(2 (zeige PTGIR Antikörper)), which exert anti-inflammatory functions.

  7. Endothelial PGI (zeige BGN Antikörper) synthase-mediated prostacyclin contributes to renal protection against endotoxemia-related acute kidney injury.

  8. identify PGI(2)-prostaglandin I2 receptor (zeige PTGIR Antikörper) as an important pathway for inhibiting allergic pulmonary inflammation by controlling recruitment of CD4 (zeige CD4 Antikörper)(+) Th2 cells into the inflammatory site

  9. COX-1 (zeige PTGS1 Antikörper) contributes to the enhanced formation of both PGI(2 (zeige PTGIR Antikörper)) and TXA(2 (zeige TBXA2R Antikörper)) in atherosclerosis, and to the development of the disease

  10. PGIS/ IP transgenic animals with lung-specific PPARgamma (zeige PPARG Antikörper) overexpression also developed fewer lung tumors.

Human Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) Interaktionspartner

  1. In examining the tumor suppressor PTGIS as a potential biomarker for treatment with either 5-Aza-dC or TSA (zeige PRDX2 Antikörper), 5-Aza-dC effectively stabilized cell cycling, restricted genetic instability and derepressed PTGIS expression

  2. Based on the predicted crystal structure of CYP8A1( *)5 using the Molecular Operating Environment platform, the distance from CYP8A1 Cys441 to the heme was altered with a significantly changed binding free energy for the mutant protein.

  3. results indicate that PGIS expression was associated with radiotherapy efficiency

  4. Type-2 diabetes is associated with higher COX-2 (zeige COX2 Antikörper) expression, but lower eNOS (zeige NOS3 Antikörper) and PGIS expression in subcutaneous arteries.

  5. In a case-control study unaffected carriers of a BMPR2 mutation, linked to pulmonary artery hypertension (PAH), were most often found to have prostacyclin synthase promoter sequence variants, which were thought to protect against PAH.

  6. These findings suggest that PGIS is induced by hypoxia and regulates the expression of VEGF in fibroblasts.

  7. High PTGIS expression is associated with colorectal cancer hepatic metastasis.

  8. The CC genotype of C1117A polymorphism is associated with higher risk of LM-CAD (zeige CAD Antikörper)

  9. Overexpression of PTGIS is associated with liver metastasis in colon cancer.

  10. diabetes preferentially increases PGIS nitration that is associated with excessive vascular inflammation in atherosclerotic carotid arteries from patients with type 2 diabetes

Zebrafish Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) Interaktionspartner

  1. crystal structures of ligand-free, inhibitor (minoxidil)-bound and substrate analog U51605-bound PGIS

Pig (Porcine) Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) Interaktionspartner

  1. Disturbances in prostacyclin synthase and its receptor may lead to disruption of the oviductal environment and, in turn, perturbed development of embryos and their transport to the uterus.

  2. Prostacyclin synthase is differentially expressed in the endometrium of cyclic and pregnant gilts resulting in higher PGI(2 (zeige PTGIR Antikörper)) synthesis in pregnant animals

  3. CRP (zeige CRP Antikörper) stimulates superoxide production and the subsequent formation of peroxynitrite from basal released nitric oxide compromises PGI(2 (zeige PTGIR Antikörper)) synthesis.

Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) Antigen-Profil

Protein Überblick

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.

Genbezeichner und Symbole assoziert mit PTGIS

  • prostacyclin synthase (VDBG_06319) Antikörper
  • prostaglandin I2 (prostacyclin) synthase (PTGIS) Antikörper
  • prostaglandin I2 (prostacyclin) synthase (Ptgis) Antikörper
  • prostaglandin I2 (prostacyclin) synthase (ptgis) Antikörper
  • CYP8 Antikörper
  • CYP8A1 Antikörper
  • PGIS Antikörper
  • PTGI Antikörper
  • PTGIS Antikörper
  • ptgisl Antikörper

Bezeichner auf Proteinebene für PTGIS

prostacyclin synthase , prostaglandin I2 (prostacyclin) synthase , prostaglandin I2 synthase , cytochrome P450, family 8, subfamily A, polypeptide 1 , prostaglandin I2 (prostacyclin) synthase like , cytochrome P450 8A1

GENE ID SPEZIES
9535224 Verticillium alfalfae VaMs.102
458323 Pan troglodytes
485919 Canis lupus familiaris
703407 Macaca mulatta
100592236 Nomascus leucogenys
282021 Bos taurus
101116418 Ovis aries
19223 Mus musculus
25527 Rattus norvegicus
100734621 Cavia porcellus
5740 Homo sapiens
559148 Danio rerio
100126284 Sus scrofa
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