Plexin B1 Proteine (PLXNB1)

Receptor for SEMA4D. Zusätzlich bieten wir Ihnen Plexin B1 Antikörper (73) und Plexin B1 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PLXNB1 235611 Q8CJH3
Ratte PLXNB1 PLXNB1 316009  
PLXNB1 5364 O43157
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Showing 5 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
640,00 €
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HOST_Escherichia coli (E. coli) Maus T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
700,95 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
818,45 €
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PLXNB1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,
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Human ,
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Weitere Proteine zu Plexin B1 (PLXNB1) Interaktionspartnern

Mouse (Murine) Plexin B1 (PLXNB1) Interaktionspartner

  1. Deletion of plexin-B1, the high affinity receptor for semaphorin 4D (zeige SEMA4D Proteine), significantly (one-way ANOVA; p < 0.001) reduced thrombus weight (- 40%) in oxidative venous thrombosis.

  2. Sema (zeige SEMA3B Proteine) 4D/CD100 (zeige SEMA4D Proteine) is not only a ligand for plexin B1 but also a direct signaling receptor in mediating Sema (zeige SEMA3B Proteine) 4D/CD100 (zeige SEMA4D Proteine)-plexin B's biological functions.

  3. In Erb (zeige ERBB2 Proteine)B-2-overexpressing murine breast cancer, ablation of Plexin-B1 genes strongly reduced metastases. Plexin-B1 has no effect on tumorigenesis o (zeige ERBB2 Proteine)r tumor growth but is require (zeige RHOA Proteine)d for m (zeige RHOC Proteine)etastasis of ErbB-2-dependent breast cancers in vivo.

  4. Semaphorin 4D (zeige SEMA4D Proteine)-induced nitric oxide synthase (iNOS (zeige NOS2 Proteine)) and nitric oxide (NO) production are mediated through plexin-B1.

  5. a lack of plexin-B1 did not impact on cortical development in vivo

  6. LARG (zeige ARHGEF12 Proteine) plays a critical role in plexin-B1 signaling to stimulate Rho activation and cytoskeletal reorganization.

  7. binding of Sema (zeige SEMA3B Proteine) 4D to Plexin B1 stimulates the tyrosine kinase (zeige TYRO3 Proteine) activity of Met

  8. Results suggest that plexin-A1 (zeige PLXNA1 Proteine) and B1 interact in the adult brain and transduce semaphorin 3A (zeige SEMA3A Proteine) signaling in cooperation.

  9. The mechanism of semaphorin D (zeige SEMA3A Proteine) in the activation of the MAPK (zeige MAPK1 Proteine) pathway via plexin-B1 is reported.

  10. A possible role for plexin-B1 in ovarian follicle growth and steroidogenesis, most likely via the granulosa cells, is suggested.

Human Plexin B1 (PLXNB1) Interaktionspartner

  1. The positive expression of both Sema4D (zeige SEMA4D Proteine) and PlexinB1 was found to be an independent risk factor for a worse survival in colorectal cancer.

  2. Loss of plexin B1 expression might play a pivotal role in enhancing the metastatic potential of breast cancer cells.

  3. Plexin B1 expression was regulated by TMPRSS2-ERG fusion gene in prostate cancer.

  4. Plexin-B1 mediates RhoA (zeige RHOA Proteine)/integrin alphavbeta3 (zeige ITGAV Proteine) involved in the PI3K (zeige PIK3CA Proteine)/Akt (zeige AKT1 Proteine) pathway and SRPK1 (zeige SRPK1 Proteine) to influence the growth of glioma cell, angiogenesis, and motility in vitro and in vivo.

  5. results show that Sema4D (zeige SEMA4D Proteine)/plexin-B1 signaling promotes the translocation of androgen receptor (zeige AR Proteine) to the nucleus and thereby enhances AR transcriptional activity

  6. Plexin-B1 induces cutaneous squamous cell carcinoma cell proliferation, migration, and invasion by interacting with Sema4D (zeige SEMA4D Proteine). Plexin-B1 might serve as a useful biomarker and/or as a novel therapeutic target for cSCC (zeige CYP11A1 Proteine).

  7. Results show that decreased expression of Sema4D (zeige SEMA4D Proteine), plexin-B1 and -B2 was associated with local recurrence and poor prognosis of breast neoplasm.

  8. Dysregulation of the vascular endothelial growth factor and semaphorin ligand-receptor families in prostate cancer metastasis

  9. Blocking of CD100 (zeige SEMA4D Proteine), plexin B1 and/or B2 in adhesion experiments have shown that both CD100 (zeige SEMA4D Proteine) and plexins act as adhesion molecules involved in monocyte-endothelial cell binding.

  10. The Semaphorin 4D (zeige SEMA4D Proteine)-Plexin-B1-RhoA (zeige RHOA Proteine) signaling axis recruits pericytes and regulates vascular permeability through endothelial production of PDGF-B (zeige PDGFB Proteine) and ANGPTL4 (zeige ANGPTL4 Proteine).

Plexin B1 (PLXNB1) Protein Überblick

Protein Überblick

Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.

Genbezeichner und Symbole assoziert mit Plexin B1 Proteine (PLXNB1)

  • plexin B1 (PLXNB1)
  • plexin b1a (plxnb1a)
  • plexin B1 (Plxnb1)
  • 2900002G15Rik Protein
  • AU042020 Protein
  • im:7054247 Protein
  • mKIAA0407 Protein
  • PLEXIN-B1 Protein
  • PLXN5 Protein
  • SEP Protein
  • si:ch211-220i18.5 Protein
  • wu:fb83a09 Protein

Bezeichner auf Proteinebene für Plexin B1 Proteine (PLXNB1)

plexin B1 , plexin b1 , plexin-B1-like , plexin-B1 , plexin 5 , semaphorin receptor SEP

GENE ID SPEZIES
416046 Gallus gallus
460344 Pan troglodytes
561012 Danio rerio
709802 Macaca mulatta
100023271 Monodelphis domestica
100053891 Equus caballus
100078327 Ornithorhynchus anatinus
100342042 Oryctolagus cuniculus
100479690 Ailuropoda melanoleuca
100589890 Nomascus leucogenys
235611 Mus musculus
316009 Rattus norvegicus
5364 Homo sapiens
476636 Canis lupus familiaris
100522643 Sus scrofa
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