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PF4 encodes a member of the CXC chemokine family. Zusätzlich bieten wir Ihnen Platelet Factor 4 Antikörper (131) und Platelet Factor 4 Kits (93) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 74 products:
Human PF4 Protein expressed in Escherichia coli (E. coli) - ABIN2666881
Lasagni, Francalanci, Annunziato, Lazzeri, Giannini, Cosmi, Sagrinati, Mazzinghi, Orlando, Maggi, Marra, Romagnani, Serio, Romagnani: An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4. in The Journal of experimental medicine 2003
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Mouse (Murine) PF4 Protein expressed in Escherichia coli (E. coli) - ABIN2666923
Maione, Gray, Petro, Hunt, Donner, Bauer, Carson, Sharpe: Inhibition of angiogenesis by recombinant human platelet factor-4 and related peptides. in Science (New York, N.Y.) 1990
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Human PF4 Protein expressed in Escherichia coli (E. coli) - ABIN2003519
ODonovan, Galvin, Morgan: Physical mapping of the CXC chemokine locus on human chromosome 4. in Cytogenetics and cell genetics 1999
CXCL4 plays an important role in pancreatic inflammation
Data suggest that serum haptoglobin, fetuin-A, platelet factor-4, hs-CRP (high sensitive-C-reactive protein), SAP (serum amyloid P), AGP (alpha1-acid glycoprotein) levels of adolescents with metabolic syndrome are significantly higher than those of controls subjects.
The hitherto unknown association of increased serum CXCL4 with features of microvascular impairment in primary Sjogren's syndrome, along with the negative association with features of lymphocytic response suggest clarifying the possible implication of this chemokine (zeige CCL1 Proteine) in primary Sjogren's syndrome pathogenesis in larger studies.
serum concentration of CXCL4 was significantly increased in patients with Chronic Liver Allograft Dysfunction (CLAD); CXCL4 mRNA was significantly increased in subjects with CLAD versus individuals without CLAD
Plasma levels of CXCL4 are associated with tumour vascularity.
Data suggest that, in patients with hypothyroid autoimmune thyroiditis, PF4/CXCL4 serum levels are significantly lower in those with subclinical hypothyroidism than in euthyroid control subjects.
Expression of CXCL4 and aquaporin 3 (zeige AQP3 Proteine) and 10 mRNAs in middle ear effusion is associated with the pathophysiology of otitis media with effusion.
PF4 changed its structure upon binding to polyP in a similar way as seen in PF4/heparin complexes. PF4/polyP complexes exposed neoepitopes to which human anti-PF4/heparin antibodies bound.
PF4 has a complex intramedullary life cycle with important implications in megakaryopoiesis and hematopoietic stem cell replication not seen with other tested alpha granule proteins.
A subset of heparin-treated patients produce subthreshold levels of platelet-activating anti-PF4/heparin antibodies that do not cause heparin-induced thrombocytopenia.
Platelet-derived CXCL7 (zeige PPBP Proteine) and CXCL4 contribute to the pathogenesis of acute lung injury.
Platelet secretion of CXCL4 is Rac1-dependent and regulates neutrophil infiltration and tissue damage in septic lung damage
Heparin enhances antigen uptake and activation of the initial steps in the cellular immune response to PF4-containing complexes.
Data indicate that platelet factor 4 (PF4) is involved directly in liver innate immune response against ischaemia-reperfusion injury (IRI) by regulating Th17 cell differentiation.
CXCL4 regulates hematopoietic stem cell cell cycle activity.
Platelet factor 4 has a role in regulating Th17 differentiation and cardiac allograft rejection
Histones regulate activated protein C (zeige PROC Proteine) formation in a manner similar to PF4 and suggest heparinoids may be benificial in sepsis.
PF4 drives a vascular smooth muscle inflammatory phenotype including a decline in differentiation markers, increased cytokine production, and cell proliferation.
This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function.
platelet factor 4 (chemokine (C-X-C motif) ligand 4)
, C-X-C motif chemokine 4
, chemokine (C-X-C motif) ligand 4