Phosphomevalonate Kinase Proteine (PMVK)

PMVK encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Zusätzlich bieten wir Ihnen Phosphomevalonate Kinase Antikörper (66) und Phosphomevalonate Kinase Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PMVK 10654 Q15126
PMVK 68603 Q9D1G2
Ratte PMVK PMVK 310645  
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Top Phosphomevalonate Kinase Proteine auf antikoerper-online.de

Showing 10 out of 14 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,331.68
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 20 bis 21 Tage
$272.80
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$319.00
Details
Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$522.50
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 12 bis 15 Tage
$460.85
Details
Escherichia coli (E. coli) Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$300.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
Details
Hefe Wildschwein His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,267.83
Details

PMVK Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Phosphomevalonate Kinase (PMVK) Interaktionspartnern

Human Phosphomevalonate Kinase (PMVK) Interaktionspartner

  1. Data indicate that exome sequencing revealed disseminated superficial porokeratosis (DSP)-associated mutations in phosphomevalonate kinase gene (PMVK).

  2. found an exclusive cytosolic localization of both endogenously expressed PMVK(in human fibroblasts, human liver, and HEK293 cells) and overexpressed PMVK. No indication of a peroxisomal localization was obtained.

  3. Functional evaluation of conserved basic residues in PMVK is reported.

  4. This is the first report of hPMK crystal structure that suggests a potential substrate binding site and a possible enzyme catalytic mechanism.

  5. Binding of mevalonate 5-phosphate causes the phosphomevalonate kinase structure to compress (tau(c) = 13.5 nsec), whereas subsequent binding of Mg-ADP opens the structure up (tau(c) = 15.6 nsec).

Phosphomevalonate Kinase (PMVK) Protein Überblick

Protein Überblick

This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.

Genbezeichner und Symbole assoziert mit PMVK

  • phosphomevalonate kinase (PMVK)
  • phosphomevalonate kinase (Mpk)
  • GHMP kinase family protein (AT1G31910)
  • phosphomevalonate kinase (CpipJ_CPIJ015413)
  • phosphomevalonate kinase (Bm1_05275)
  • phosphomevalonate kinase (pmvk)
  • phosphomevalonate kinase (LOAG_11811)
  • phosphomevalonate kinase (Tsp_06629)
  • phosphomevalonate kinase (LOC100282968)
  • phosphomevalonate kinase (Pmvk)
  • 1110011E12Rik Protein
  • 2900002L22Rik Protein
  • AV001327 Protein
  • F5M6.9 Protein
  • F5M6_9 Protein
  • HUMPMKI Protein
  • MPK_Bm Protein
  • PMK Protein
  • PMKA Protein
  • PMKASE Protein
  • zgc:162701 Protein

Bezeichner auf Proteinebene für PMVK

phosphomevalonate kinase , hPMK , PMKase

GENE ID SPEZIES
457350 Pan troglodytes
612251 Canis lupus familiaris
692835 Bombyx mori
717014 Macaca mulatta
840081 Arabidopsis thaliana
6049213 Culex quinquefasciatus
6095986 Brugia malayi
8570979 Lactobacillus johnsonii FI9785
9949270 Loa loa
10909538 Trichinella spiralis
100003383 Danio rerio
100282968 Zea mays
10654 Homo sapiens
68603 Mus musculus
310645 Rattus norvegicus
100152301 Sus scrofa
513533 Bos taurus
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