anti-Phosphomevalonate Kinase (PMVK) Antikörper

PMVK encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Zusätzlich bieten wir Ihnen Phosphomevalonate Kinase Proteine (16) und Phosphomevalonate Kinase Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PMVK 10654 Q15126
PMVK 68603 Q9D1G2
PMVK 310645  
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Top anti-Phosphomevalonate Kinase Antikörper auf antikoerper-online.de

Showing 10 out of 66 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Ratte Kaninchen Unkonjugiert IHC (p), WB Anti-PMVK antibody, Western blotting WB: Rat Cardiac Muscle Tissue Lysate Anti-PMVK antibody, IHC(P) IHC(P): Rat Skeletal Muscle Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB Immunohistochemical analysis of paraffin embedded rat skeletal muscle sections, staining PMVK in cytoplasm, DAB chromeric reaction Western blot analysis of cardiac muscle tissue lysis using PMKV antibody 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$313.50
Details
Human Maus Unkonjugiert IF, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PMVK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PMVK. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$423.50
Details
Human Maus Unkonjugiert FACS, IF, WB HEK293T cells transfected with either RC202867 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PMVK antibody (ABIN2454969), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PMVK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PMVK. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$423.50
Details
Human Maus Unkonjugiert WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PMVK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PMVK. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$482.90
Details
Human Maus Unkonjugiert IF, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human kidney labeled with Rabbit Anti-PMVK Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Human Maus Unkonjugiert WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$529.83
Details
Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Cy5 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

PMVK Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Weitere Antikörper gegen Phosphomevalonate Kinase Interaktionspartner

Human Phosphomevalonate Kinase (PMVK) Interaktionspartner

  1. Data indicate that exome sequencing revealed disseminated superficial porokeratosis (DSP (zeige DSP Antikörper))-associated mutations in phosphomevalonate kinase gene (PMVK).

  2. found an exclusive cytosolic localization of both endogenously expressed PMVK(in human fibroblasts, human liver, and HEK293 cells) and overexpressed PMVK. No indication of a peroxisomal localization was obtained.

  3. Functional evaluation of conserved basic residues in PMVK is reported.

  4. This is the first report of hPMK crystal structure that suggests a potential substrate binding site and a possible enzyme catalytic mechanism.

  5. Binding of mevalonate 5-phosphate causes the phosphomevalonate kinase structure to compress (tau(c) = 13.5 nsec), whereas subsequent binding of Mg-ADP opens the structure up (tau(c) = 15.6 nsec).

Phosphomevalonate Kinase (PMVK) Antigen-Profil

Protein Überblick

This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.

Genbezeichner und Symbole assoziert mit PMVK

  • phosphomevalonate kinase (PMVK) Antikörper
  • phosphomevalonate kinase (Mpk) Antikörper
  • GHMP kinase family protein (AT1G31910) Antikörper
  • phosphomevalonate kinase (CpipJ_CPIJ015413) Antikörper
  • phosphomevalonate kinase (Bm1_05275) Antikörper
  • phosphomevalonate kinase (pmvk) Antikörper
  • phosphomevalonate kinase (LOAG_11811) Antikörper
  • phosphomevalonate kinase (Tsp_06629) Antikörper
  • phosphomevalonate kinase (LOC100282968) Antikörper
  • phosphomevalonate kinase (Pmvk) Antikörper
  • 1110011E12Rik Antikörper
  • 2900002L22Rik Antikörper
  • AV001327 Antikörper
  • F5M6.9 Antikörper
  • F5M6_9 Antikörper
  • HUMPMKI Antikörper
  • MPK_Bm Antikörper
  • PMK Antikörper
  • PMKA Antikörper
  • PMKASE Antikörper
  • zgc:162701 Antikörper

Bezeichner auf Proteinebene für PMVK

phosphomevalonate kinase , hPMK , PMKase

GENE ID SPEZIES
457350 Pan troglodytes
612251 Canis lupus familiaris
692835 Bombyx mori
717014 Macaca mulatta
840081 Arabidopsis thaliana
6049213 Culex quinquefasciatus
6095986 Brugia malayi
8570979 Lactobacillus johnsonii FI9785
9949270 Loa loa
10909538 Trichinella spiralis
100003383 Danio rerio
100282968 Zea mays
10654 Homo sapiens
68603 Mus musculus
310645 Rattus norvegicus
100152301 Sus scrofa
513533 Bos taurus
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