anti-Peripherin (PRPH) Antikörper

PRPH encodes a cytoskeletal protein found in neurons of the peripheral nervous system. Zusätzlich bieten wir Ihnen Peripherin Kits (13) und Peripherin Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PRPH 5630 P41219
PRPH 19132  
PRPH 24688  
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Top anti-Peripherin Antikörper auf

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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PRPH Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human heart 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PRPH Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells, using Peripherin Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Peripherin Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert ICC, IHC (fro), IF, IHC (p), IHC, ELISA, WB Detection of the 57 kDa peripherin protein in whole rat brain stem homogenate using ABIN152483 (1:20,000).  The faint 48 kDa band is a peripherin molecule. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Maus Unkonjugiert ICC, IF, ELISA, WB   0.5 mL Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE Peripherin antibody antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
Hund Huhn Unkonjugiert IF, WB Rat mixed neuron/glial cultures stained with Peripherin antibody (Green channel) and Neurofilament alpha-internexin/NF66 antibody (green channel). These cultures contain mostly neurons which are rich in alpha-internexin, and a subgroup which have a large amount of peripherin also, such as the prominent cell in the middle of the micrograph. Since this cell expresses large amounts of peripherin and alpha-internexin, the green and red signals superimpose to produce a golden cell. Blue is a DNA stain. 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cells, using PRPH antibody. Immunohistochemistry of paraffin-embedded rat heart using PRPH antibody at dilution of 1:100 (x40 lens). 100 μL Anmelden zum Anzeigen 16 Days

PRPH Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
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Mouse (Murine) , ,
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Rat (Rattus) ,
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Am meisten referenzierte anti-Peripherin Antikörper

  1. Human Polyclonal Peripherin Primary Antibody für ICC, IHC (fro) - ABIN152483 : Burgess, Jucius, Ackerman: Motor axon guidance of the mammalian trochlear and phrenic nerves: dependence on the netrin receptor Unc5c and modifier loci. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 5 Pubmed References

  2. Polyclonal Peripherin Primary Antibody für IHC (fro), IF - ABIN540386 : Arvanian, Bowers, Petruska, Motin, Manuzon, Narrow, Federoff, Mendell: Viral delivery of NR2D subunits reduces Mg2+ block of NMDA receptor and restores NT-3-induced potentiation of AMPA-kainate responses in maturing rat motoneurons. in Journal of neurophysiology 2004 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal Peripherin Primary Antibody für ICC, IF - ABIN152484 : Errante, Wiche, Shaw: Distribution of plectin, an intermediate filament-associated protein, in the adult rat central nervous system. in Journal of neuroscience research 1994 (PubMed)

  4. Human Polyclonal Peripherin Primary Antibody für IHC, ELISA - ABIN1533379 : Sekino, Nakano, Hamaue, Chuganji, Sakamoto, Yoshimura, Origuchi, Okita: Sensory hyperinnervation and increase in NGF, TRPV1 and P2X3 expression in the epidermis following cast immobilization in rats. in European journal of pain (London, England) 2014 (PubMed)

Weitere Antikörper gegen Peripherin Interaktionspartner

Human Peripherin (PRPH) Interaktionspartner

  1. To discover of Phosphorylated autoantigens Peripherin as a Major Humoral Autoantigen in Type 1 Diabetes Mellitus.

  2. In patients with HD, a panel using calretinin and peripherin with or without MAP-2 may be most helpful in identifying transition zones

  3. interaction between disease-causing RAB7A (zeige RAB7A Antikörper) mutants and peripherin could play an important role in Charcot-Marie-Tooth type 2B neuropathy

  4. This work contributes to determine the role of PRPH gene variants in ALS. Further studies are necessary to define the mechanisms through which the mutant peripherin could cause ALS phenotype.

  5. study analyzed expression of peripherin(PP) in the cochlea; in organ of Corti, PP seems to be specifically expressed in outer hair cell afferents; small or type II spiral ganglion cell bodies also intensely express PP

  6. although the mechanisms underlying peripherin co-localization in Bunina bodies are unknown, peripherin could be involved in forming these inclusions

  7. Transgenic peripherin isoform expression reveals post-transcriptional changes to the normal expression pattern associated with malformed filaments and intracellular inclusions underlying a role in the pathogenesis of amyotrophic lateral sclerosis.

  8. The data of this experiment document the expression of peripherin in Lewy body-like inclusions , which may provide a clue to the pathogenesis of neurodegeneration in ALS.

  9. Peripherin overexpression in transgenic mice can cause defective transport of type IV neurofilament proteins, a phenomenon that may account for the progressive formation of amyotrophic lateral sclerosis-like spheroids in axons.

  10. peripherin is a novel substrate for Akt (zeige AKT1 Antikörper) in vivo and its phosphorylation may play a role in motor nerve regeneration

Mouse (Murine) Peripherin (PRPH) Interaktionspartner

  1. ablation of Rom1 (zeige ROM1 Antikörper) results in the conversion of an MD/PD phenotype characterized by cone functional defects and the formation of abnormal Prph2 (zeige PRPH2 Antikörper)/Rom1 (zeige ROM1 Antikörper) complexes to an RP phenotype characterized by rod-dominant functional defects and reductions in total Prph2 (zeige PRPH2 Antikörper) protein. Thus one method by which ROM1 (zeige ROM1 Antikörper) may act as a disease modifier is by contributing to the large variability in PRPH2 (zeige PRPH2 Antikörper)-associated disease phenotype

  2. quantitative FRET analysis in acutely isolated cone OS revealed that the cone degeneration-causing V268I mutation in peripherin-2 (zeige PRPH2 Antikörper) selectively reduced binding to M-opsin without affecting the peripherin-2 (zeige PRPH2 Antikörper) interaction to S-opsin (zeige OPN1SW Antikörper) or rhodopsin (zeige RHO Antikörper)

  3. These results support the idea that mutations may differentially affect Prph2 (zeige PRPH2 Antikörper)'s role as a structural component, and its role as a functional protein key for organizing membrane domains for cellular signalling. These roles may be different in rods and cones, thus contributing to the phenotypic heterogeneity that characterizes diseases associated with Prph2 (zeige PRPH2 Antikörper) mutations.

  4. Data suggest that the underlying molecular mechanisms in amyotrophic lateral sclerosis pathogenesis involve peripherin mis (zeige AMH Antikörper)-splicing and altered homeostasis of nerve fibers.

  5. Eliminating Cngb1 (zeige CNGB1 Antikörper) and reducing RDS (zeige PRPH2 Antikörper) leads to additive defects in RDS (zeige PRPH2 Antikörper) expression levels and rod electroretinogram (ERG (zeige ERG Antikörper)) function, (e.g., Cngb1 (zeige CNGB1 Antikörper)-/-/rds (zeige PRPH2 Antikörper)+/- versus rds (zeige PRPH2 Antikörper)+/- or Cngb1 (zeige CNGB1 Antikörper)-/-) but not to additive defects in rod ultrastructure.

  6. In the group of mice manifesting homozygous mutation in the PRPH2 (zeige PRPH2 Antikörper) gene.

  7. Our data suggest that upregulation of PRPH2 (zeige PRPH2 Antikörper) levels in combination with defects in the PRPH2 (zeige PRPH2 Antikörper) function caused by the mutation might be an important mechanism leading to cone degeneration.

  8. Contralateral and ipsilateral olivocochlear efferent-mediated suppression of the cochlear amplifier were absent in Prph null mice.

  9. These data suggest that glycosylation of RDS (zeige PRPH2 Antikörper) is required for RDS (zeige PRPH2 Antikörper) function or stability in cones, a difference that may be due to extracellular versus intradiscal localization of the RDS (zeige PRPH2 Antikörper) glycan in cones versus rods.

  10. Peripherin-2 (zeige PRPH2 Antikörper) links CNGB1 (zeige CNGB1 Antikörper) to the light-detector rhodopsin (zeige RHO Antikörper) in outer segments of rod photoreceptors.

Peripherin (PRPH) Antigen-Profil

Protein Überblick

This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis.

Genbezeichner und Symbole assoziert mit anti-Peripherin (PRPH) Antikörper

  • peripherin (PRPH) Antikörper
  • peripherin (prph) Antikörper
  • peripherin (Prph) Antikörper
  • peripherin L homeolog (prph.L) Antikörper
  • peripherin 2 (Prph2) Antikörper
  • AOFMD Antikörper
  • AVMD Antikörper
  • if3 Antikörper
  • MGC69454 Antikörper
  • NEF4 Antikörper
  • Nmf193 Antikörper
  • Perf Antikörper
  • plasticin Antikörper
  • PRPH Antikörper
  • Prph1 Antikörper
  • Rd-2 Antikörper
  • Rd2 Antikörper
  • rds Antikörper
  • RP7 Antikörper
  • Tspan22 Antikörper

Bezeichner auf Proteinebene für anti-Peripherin (PRPH) Antikörper

peripherin , peripherin 1 , neurofilament 4 (57kD) , neuronal intermediate filament IF3 , peripherin-2 , retinal degeneration 2 , retinal degeneration slow protein , retinal degeneration, slow (retinitis pigmentosa 7)

100059208 Equus caballus
407916 Xenopus (Silurana) tropicalis
5630 Homo sapiens
510082 Bos taurus
19132 Mus musculus
24688 Rattus norvegicus
477618 Canis lupus familiaris
100152434 Sus scrofa
380221 Xenopus laevis
100357822 Oryctolagus cuniculus
101082247 Felis catus
19133 Mus musculus
Ausgewählte Anbieter für anti-Peripherin (PRPH) Antikörper
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