Paraoxonase 1 Proteine (PON1)

The enzyme encoded by PON1 is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Zusätzlich bieten wir Ihnen Paraoxonase 1 Antikörper (172) und Paraoxonase 1 Kits (69) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PON1 5444 P27169
PON1 18979 P52430
PON1 84024 P55159
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Top Paraoxonase 1 Proteine auf antikoerper-online.de

Showing 10 out of 25 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
Details
Escherichia coli (E. coli) Human Unkonjugiert   0.01 mg Anmelden zum Anzeigen 2 bis 6 Tage
$270.00
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Escherichia coli (E. coli) Human GST tag   50 μg Anmelden zum Anzeigen 11 Days
$341.00
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Escherichia coli (E. coli) Maus His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$752.00
Details
Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$784.00
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Escherichia coli (E. coli) Human His tag   100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$1,472.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$723.00
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$860.20
Details

PON1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Rat (Rattus) ,

Weitere Proteine zu Paraoxonase 1 (PON1) Interaktionspartnern

Human Paraoxonase 1 (PON1) Interaktionspartner

  1. Genotype RR of PON1 Q192R is an independent risk factor predicting re-stenting in Chinese acute coronary syndrome patients after coronary stenting

  2. Clinical observations focusing on gene polymorphisms of PON indicate that three different genotypes of polymorphism PON1Q192R have unequal degrees atheroprotective properties.

  3. the measurement of serum PON1 concentration post-radiotherapy (RT) could be an efficient prognostic biomarker, and may be used as an index of the efficacy of the RT.

  4. Patients with the Q allele of the PON1 Q192R polymorphism who were treated with statins exhibited improvement in glucose metabolism, especially in insulin (zeige INS Proteine) secretion, suggesting the importance of genotyping PON1 Q192R to identify those who could benefit from statin therapy.

  5. PON1 and CYP2C19 (zeige CYP2C19 Proteine) polymorphisms were associated with lower clopidogrel responsiveness in this sample.

  6. generated a meta-marker model made up of SERPINA4 (zeige SERPINA4 Proteine) and PON1 that is useful as a differential diagnostic biomarker differentiating lung cancer from other lung diseases.

  7. Our study showed that although lipoic acid up-regulates PON3 (zeige PON3 Proteine) but down-regulates PON1 mRNA expression, it increases both PON1 and PON3 (zeige PON3 Proteine) protein levels and arylesterase activity in HepG2 cells. We can report that lipoic acid may be useful for preventing atherosclerosis at therapeutic doses.

  8. Prenatal pesticide exposure was associated with higher adolescent body fat content, including android fat deposition, independent of puberty. Girls appeared more susceptible than boys. Furthermore, the association depended on maternal and child PON1 Q192R genotype.

  9. PON1 575GG genotype was found to influence the risk of Ischemic Heart Failure.

  10. PON1 rs662 polymorphism is significantly correlated with increased ankylosing spondylitis risk via inhibiting PON1 activity.

Mouse (Murine) Paraoxonase 1 (PON1) Interaktionspartner

  1. PON1 overexpression protects against AAA (zeige AAAS Proteine) progression by reducing oxidative stress, apoptosis and inflammation

  2. Paraoxonase 1 (PON1) influence circadian gene expression and period length

  3. results suggest that Hyperhomocysteinemia plays an intricate role in dysfunctional HDL (zeige HSD11B1 Proteine), owing to the lack of PON1. This contributes to vascular endothelial impairment and atherosclerosis.

  4. Maternal PON1 status modulates the effects of repeated gestational chlorpyrifos oxon exposure on fetal-brain gene expression and on inhibition of both maternal and fetal biomarker enzymes.

  5. 5,6-dihydroxyeicosatrienoate-1,5-lactone, a stable metabolite of arachidonic acid, is a potential substrate for PON1.

  6. HDL (zeige HSD11B1 Proteine) (mostly HDL3), stimulates PON1 antiatherogenic activities in mouse macrophages.

  7. Findings suggest that Pon1 interacts with diverse cellular processes from energy metabolism and anti-oxidative defenses to cell cycle, cytoskeleton dynamics, and synaptic plasticity essential for normal brain homeostasis

  8. The study demonstrated a significant decline in PON1 activity which correlates with increased LDL oxidation after 8 months of age in Wistar rats.

  9. PON1 plays a protective role against hepatic derangements, secondary to fat and cholesterol overnutrition. PON1 deficiency is associated with oxidative stress and metabolic alterations leading to liver steatosis.

  10. PON1 is not essential for normal development, function, ageing, and the defense against light damage of the mouse retina.

Pig (Porcine) Paraoxonase 1 (PON1) Interaktionspartner

  1. PON1 behaves as a negative acute phase protein (zeige ORM1 Proteine) in pigs since a significant decrease (P<0.05) in its activity after 72 h of the induction of the inflammation was observed with all substrates.

Cow (Bovine) Paraoxonase 1 (PON1) Interaktionspartner

  1. characterization the SNPs in the promoter region of the bovine PON1 gene, and to evaluation of association with serum PON1 activity in periparturient Holstein cows

  2. The results suggest that PON1 might be a better parameter for minimal redox state changes in serum, shortly after labour in the examined breeds.

  3. Data indicate that Cu(2+), Mn(2+), Zn(2+), Ni(2 (zeige VMP1 Proteine)+), and Pb(2+) were found to inhibite the paraoxonase 1 (PON1) enzyme activity in a concentration-dependent fashion.

  4. The aim of this study was to evaluate expression of the natural anti-oxidants paraoxonase (PON) 1, 2 and 3 in granulosa cells and PON1 activity in follicular fluid and plasma of dairy cows.

  5. Significantly lower PON1 activity and PON1/high density lipoprotein ratio in lactating cows compared to heifers showed that metabolic efforts during pregnancy, parturition and lactation influence PON1 activity due to oxidative stress.

  6. The activity of PON1 and malondialdehyde in late pregnancy and early lactation in dairy cattle is reported.

Rabbit Paraoxonase 1 (PON1) Interaktionspartner

  1. ApoE (zeige APOE Proteine) mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL (zeige HSD11B1 Proteine) paraoxonase activity

  2. PON1 can decrease the AChE inhibition, and alleviated clinical signs and tissue damage caused by dichlorvos.

Paraoxonase 1 (PON1) Protein Überblick

Protein Überblick

The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.

Genbezeichner und Symbole assoziert mit Paraoxonase 1 Proteine (PON1)

  • paraoxonase 2 (pon2)
  • paraoxonase 1 (PON1)
  • paraoxonase 1 (Pon1)
  • ESA Protein
  • MGC53915 Protein
  • MGC89222 Protein
  • MVCD5 Protein
  • Pon Protein
  • PON1 Protein
  • pon2 Protein

Bezeichner auf Proteinebene für Paraoxonase 1 Proteine (PON1)

paraoxonase 1 , paraoxonase 2 , serum paraoxonase/arylesterase 1-like , A-esterase 1 , K-45 , PON 1 , aromatic esterase 1 , arylesterase B-type , esterase A , paraoxonase B-type , serum aryldiakylphosphatase , serum aryldialkylphosphatase 1 , serum paraoxonase/arylesterase 1 , serum paraoxonase

GENE ID SPEZIES
448598 Xenopus (Silurana) tropicalis
463547 Pan troglodytes
699355 Macaca mulatta
100408915 Callithrix jacchus
100436640 Pongo abelii
100602768 Nomascus leucogenys
5444 Homo sapiens
18979 Mus musculus
84024 Rattus norvegicus
475234 Canis lupus familiaris
100048952 Sus scrofa
523798 Bos taurus
100009133 Oryctolagus cuniculus
100721268 Cavia porcellus
101116983 Ovis aries
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