anti-PDS5, Regulator of Cohesion Maintenance, Homolog B (S. Cerevisiae) (PDS5B) Antikörper

PDS5B encodes a protein that interacts with the conserved protein complex termed cohesion. Zusätzlich bieten wir Ihnen PDS5B Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PDS5B 23047 Q9NTI5
PDS5B 304218  
PDS5B 100710 Q4VA53
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Top anti-PDS5B Antikörper auf antikoerper-online.de

Showing 10 out of 25 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PDS5B Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>721_B cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Western Blot and Immunoprecipitation: Pds5B Antibody [ABIN152174] - Detection of Human and Mouse Pds5B by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB in A, 1 mg for IP in B, 1/4 of IP reaction loaded), 293T (T, 50 mcg for WB) and NIH3T3 (M, 50 mcg for WB) cells. Antibodies: Affinity purified rabbit anti- Pds5B antibody ABIN152174  used in WB at 0.04 mcg/ml (A) or 0.1 mcg/ml (B) and for IP at 3 mcg/mg lysate (B). Pds5B was also immunoprecipitated using rabbit anti- Pds5B antibody ABIN152173 at 3 mcg/mg lysate. Detection: Chemiluminescence with exposure times of 10 seconds and 3 minutes (A) and 10 seconds (B). Western Blot and Immunoprecipitation: Pds5B Antibody [ABIN152174] - Detection of Human and Mouse Pds5B by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB in A, 1 mg for IP in B, 1/4 of IP reaction loaded), 293T (T, 50 mcg for WB) and NIH3T3 (M, 50 mcg for WB) cells. Antibodies: Affinity purified rabbit anti- Pds5B antibody ABIN152174  used in WB at 0.04 mcg/ml (A) or 0.1 mcg/ml (B) and for IP at 3 mcg/mg lysate (B). Pds5B was also immunoprecipitated using rabbit anti- Pds5B antibody ABIN152173 at 3 mcg/mg lysate. Detection: Chemiluminescence with exposure times of 10 seconds and 3 minutes (A) and 10 seconds (B). 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert WB Western Blot: APRIN Antibody [NBP2-15436] - Sample (50 ug of whole cell lysate) A: Mouse brain 5% SDS PAGE; antibody diluted at 1:1000. Western Blot: APRIN Antibody [NBP2-15436] - Sample (30 ug of whole cell lysate) A: Raji 5% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Maus Unkonjugiert DB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$285.71
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: APRIN Antibody [NBP1-90122] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells). Immunocytochemistry/Immunofluorescence: APRIN Antibody [NBP1-90122] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: APRIN Antibody [NBP1-90121] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli. Immunohistochemistry-Paraffin: APRIN Antibody [NBP1-90121] - Staining of human kidney shows strong nuclear positivity in cells in tubules and cells in glomeruli. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB   100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Human Kaninchen Unkonjugiert WB PDS5B antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details
Human Kaninchen Unkonjugiert WB Western Blot at 1:2000 dilution Lane 1: 293T/17 whole cell lysate Lane 2: DU145 whole cell lysate Lane 3: LNCaP whole cell lysate Lane 4: Raji whole cell lysate Lane 5: U-2OS whole cell lysate Lane 6: Hela whole cell lysate Lysates/proteins at 20 ug per lane. 200 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details

PDS5B Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human , ,
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Rat (Rattus)


Mouse (Murine) ,


Am meisten referenzierte anti-PDS5B Antikörper

  1. Human Polyclonal PDS5B Primary Antibody für ICC, IF - ABIN152174 : Brough, Bajrami, Vatcheva, Natrajan, Reis-Filho, Lord, Ashworth: APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer. in The EMBO journal 2012 (PubMed)

Weitere Antikörper gegen PDS5B Interaktionspartner

Human PDS5, Regulator of Cohesion Maintenance, Homolog B (S. Cerevisiae) (PDS5B) Interaktionspartner

  1. Pds5 stabilizes a transient, open state of cohesin to promote its release from chromosomes.

  2. APRIN expression levels correlate with a better survival in ovarian cancer patients and that APRIN depletion sensitizes cells to the PARP (zeige COL11A2 Antikörper) inhibitor Olaparib in xenografted zebrafish.

  3. Frameshift mutations of SGOL1 and PDS5B and the loss of their expression may be a feature of gastric and colorectal cancers with high microsatellite instability.

  4. Here, the authors use proteomic profiling to identify APRIN (PDS5B), a cohesion-associated protein, as a BRCA2-associated protein.

  5. Loss of a cohesin-linked suppressor APRIN (Pds5b) disrupts stem cell programs in embryonal carcinoma.

  6. AS3 is a mediator of the proliferative arrest in the normal rat prostate in situ and that its expression is androgen-induced (AS3 protein)

  7. The results of this study indicate that the aberrant expression of AS3 may be involved in the tumorigenesis of esophagus and is responsible for the male predominance of ESCC.

  8. identified a functional missense mutation (R1292Q) in the PDS5B DNA-binding domain in a family with Cornelia de Lange syndrome, in which affected individuals also develop megacolon

  9. Pard-3 and AS3 genes are mutationally inactivated in prostate cancer cells.

Mouse (Murine) PDS5, Regulator of Cohesion Maintenance, Homolog B (S. Cerevisiae) (PDS5B) Interaktionspartner

  1. findings demonstrate that Her2+/+ mice, similar to Pds5b-/- mice, are embryonic lethal and confirm the necessity for Pds5b in embryonic development

  2. reduced accumulation of Aurora B (zeige AURKC Antikörper) at the inner centromere region in cells lacking Pds5B impairs its error correction function, promoting chromosome mis (zeige AMH Antikörper)-segregation and aneuploidy

  3. demonstrates that overexpression of APRIN inhibits differentiation and proliferation and promotes apoptosis in P19 (zeige CDKN2D Antikörper) embryonal carcinoma cells.

  4. A paper used gene targeting in mice to demonstrate the function of PDS5B in embryonic development.

  5. APRIN, in addition to its Pds5 similarity, has the features and localization of a hormone-induced chromatin regulator.

  6. While Pds5A(-/-) and Pds5B(-/-) mice die at birth, embryos harboring 3 mutant Pds5 alleles die between E11.5 and E12.5 most likely of heart failure, indicating that total Pds5 gene dosage is critical for normal development.

PDS5B Antigen-Profil

Protein Überblick

This gene encodes a protein that interacts with the conserved protein complex termed cohesion. The cohesion complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene.

Genbezeichner und Symbole assoziert mit PDS5B

  • PDS5 cohesin associated factor B (PDS5B) Antikörper
  • PDS5 cohesin associated factor B (Pds5b) Antikörper
  • PDS5 cohesin associated factor B (pds5b) Antikörper
  • PDS5 cohesin associated factor B L homeolog (pds5b.L) Antikörper
  • AI646570 Antikörper
  • aprin Antikörper
  • as3 Antikörper
  • AW212954 Antikörper
  • CG008 Antikörper
  • mKIAA0979 Antikörper
  • pds5b Antikörper

Bezeichner auf Proteinebene für PDS5B

androgen induced inhibitor of proliferation , androgen-induced proliferation inhibitor , androgen-induced prostate proliferative shutoff-associated protein AS3 , androgen-induced shutoff 3 , sister chromatid cohesion protein PDS5 homolog B , androgen-induced prostate proliferative shutoff associated protein , PDS5, regulator of cohesion maintenance, homolog B , androgen-induced prostate proliferative shutoff associated protein AS3 , androgen-induced proliferation inhibitor A , sister chromatid cohesion protein PDS5 homolog B-A , sister chromatid cohesion protein Pds5B

GENE ID SPEZIES
23047 Homo sapiens
304218 Rattus norvegicus
418910 Gallus gallus
100135353 Xenopus (Silurana) tropicalis
100710 Mus musculus
734718 Xenopus laevis
486014 Canis lupus familiaris
Ausgewählte Anbieter für anti-PDS5B (PDS5B) Antikörper
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