anti-Osteopetrosis Associated Transmembrane Protein 1 (OSTM1) Antikörper

OSTM1 encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. Zusätzlich bieten wir Ihnen OSTM1 Proteine (10) und OSTM1 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
OSTM1 28962 Q86WC4
OSTM1 14628 Q8BGT0
OSTM1 499474  
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Top anti-OSTM1 Antikörper auf antikoerper-online.de

Showing 10 out of 53 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$218.90
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: OSTM1 Antibody [NBP1-81829] - Staining of human liver shows strong granular cytoplasmic positivity in hepatocytes. Immunocytochemistry/Immunofluorescence: OSTM1 Antibody [NBP1-81829] - Staining of human cell line A-431 shows positivity in nucleus, cytoplasm & vesicles. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat kidney labeled with Rabbit Anti OSTM1 Polyclonal Antibody, Unconjugated (ABIN1387308) at 1:200 followed by conjugation to the secondary antibody and DAB staining L1 human colon carcinoma lysates probed with Anti OSTM1 Polyclonal Antibody, Unconjugated (ABIN1387308) at 1:200 overnight at 4 °C. Followed by conjugation to secondary antibody at 1:3000 for 90 min at 37 °C. Predicted band 37kD. Observed band size:37kD. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Human Kaninchen Unkonjugiert WB OSTM1 Antibody (C-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the OSTM1  Antibody detected the OSTM1  protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$163.90
Details
Human Kaninchen Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$273.90
Details
Human Kaninchen Unkonjugiert WB Western Blot: OSTM1 Antibody [NBP2-19641] - Sample (30 ug of whole cell lysate) A: Raji B: HL-60 10% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details
Human Kaninchen Cy5 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

OSTM1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-OSTM1 Antikörper

  1. Human Polyclonal OSTM1 Primary Antibody für ICC, IF - ABIN4341943 : Majumdar, Capetillo-Zarate, Cruz, Gouras, Maxfield: Degradation of Alzheimer's amyloid fibrils by microglia requires delivery of ClC-7 to lysosomes. in Molecular biology of the cell 2011 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen OSTM1 Interaktionspartner

Human Osteopetrosis Associated Transmembrane Protein 1 (OSTM1) Interaktionspartner

  1. KIF5B (zeige KIF5B Antikörper) is essential for Ostm1 intracellular dispersion.

  2. Ostm1 has a primary and autonomous role in neuronal homeostasis

  3. Common gating underlies the slow voltage activation of ClC-7 (zeige CLCN7 Antikörper).

  4. we describe for the first time homozygous microdeletions of different sizes affecting the OSTM1 gene in two unrelated consanguineous families with children suffering from neuronopathic infantile malignant osteopetrosi

  5. The authors show that both the aminoterminus and transmembrane span of the Ostm1 beta-subunit (zeige POLG Antikörper) are required for ClC-7 (zeige CLCN7 Antikörper) Cl(-)/H(+)-exchange, whereas the Ostm1 transmembrane domain suffices for its ClC-7 (zeige CLCN7 Antikörper)-dependent trafficking to lysosomes.

  6. mutation in the human GL gene leads to severe recessive osteopetros (zeige CSF1 Antikörper)is

  7. The human GIPN gene has 6 exons and 5 introns, and encodes a 334-aa protein.

  8. A novel mutation affecting the OSTM1 locus responsible for ARO (zeige CYP19A1 Antikörper). In addition to common clinical features of osteopetrosis (zeige CSF1 Antikörper), the patient developed a unique neuronal pathology that provided evidence for the role of OSTM1 in normal neuronal cell development.

  9. This study reports on a 12-month-old female with recessive OSMT1 mutations and neuroimaging findings suggesting a malignant infantile osteopetrosis (zeige CSF1 Antikörper).

  10. mutations in OSTM1 such as the C-terminal deletion mutant studied herein provoke dysregulation of the canonical Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling pathway, providing a molecular basis for severe autosomal recessive osteopetrosis (zeige CSF1 Antikörper)

Mouse (Murine) Osteopetrosis Associated Transmembrane Protein 1 (OSTM1) Interaktionspartner

  1. KIF5B (zeige KIF5B Antikörper) is essential for Ostm1 intracellular dispersion.

  2. Truncated OSTM1 significantly inhibited the expression of osteoclast marker genes through the down-regulation of the BLIMP1 (zeige PRDM1 Antikörper)-NFATc1 (zeige NFATC1 Antikörper) axis.

  3. Our in vivo structure-function analysis of ClC-7 (zeige CLCN7 Antikörper) reveals that both protein-protein interactions and ion transport must be considered in the pathogenesis of ClC-7 (zeige CLCN7 Antikörper)-related diseases.

  4. Ostm1 has a primary and autonomous role in neuronal homeostasis

  5. Omi (zeige HTRA2 Antikörper) is a recessive mutation in the Ostm1 gene affecting teeth and coat color.

  6. Ostm1 is a bona fide target of miR (zeige MLXIP Antikörper)-140, which is significantly decreased during adipogenic differentiation.

  7. Neuropathologic changes similar to neuronal ceroid lipofuscinosis (zeige CLN6 Antikörper) are found in osteoporosis associated transmembrane protein 1 (zeige TMEM1 Antikörper) (Ostml)-deficient mice.

  8. mutation induces severe malignant autosomal recessive osteopetrosis (zeige CSF1 Antikörper); studies show that Gl protein function is absolutely required for osteoclast and melanocyte maturation and function

  9. both ClC-7 (zeige CLCN7 Antikörper) and Ostm1 proteins co-localize in late endosomes and lysosomes of various tissues, as well as in the ruffled border of bone-resorbing osteoclasts

  10. microphthalmia transcription factor (zeige MITF Antikörper) regulates Clcn7 and Ostm1 expression in osteoclasts

OSTM1 Antigen-Profil

Protein Überblick

This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.

Genbezeichner und Symbole assoziert mit OSTM1

  • osteopetrosis associated transmembrane protein 1 (OSTM1) Antikörper
  • osteopetrosis associated transmembrane protein 1 (ostm1) Antikörper
  • osteopetrosis associated transmembrane protein 1 (Ostm1) Antikörper
  • 1200002H13Rik Antikörper
  • Gipn Antikörper
  • gl Antikörper
  • HSPC019 Antikörper
  • MGC145644 Antikörper
  • OPTB5 Antikörper
  • OSTM1 Antikörper
  • si:ch73-257c13.3 Antikörper

Bezeichner auf Proteinebene für OSTM1

osteopetrosis-associated transmembrane protein 1 , osteopetrosis associated transmembrane protein 1 , GAIP-interacting protein N terminus , chloride channel 7 beta subunit , grey-lethal osteopetrosis , grey lethal osteopetrosis , GAIP interacting protein N terminus , osteopetrosis associated transmembrane protein 1-like

GENE ID SPEZIES
421773 Gallus gallus
518522 Bos taurus
701341 Macaca mulatta
739203 Pan troglodytes
780037 Xenopus (Silurana) tropicalis
100137453 Papio anubis
100320445 Danio rerio
100328697 Oryctolagus cuniculus
28962 Homo sapiens
14628 Mus musculus
499474 Rattus norvegicus
100049681 Sus scrofa
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