Opsin 1 (Cone Pigments), Short-Wave-Sensitive Proteine (OPN1SW)

OPN1SW belongs to the G-protein coupled receptor 1 family, opsin subfamily. Zusätzlich bieten wir Ihnen OPN1SW Antikörper (2) und OPN1SW Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
OPN1SW 611 P03999
Ratte OPN1SW OPN1SW 81644 Q63652
OPN1SW 12057 P51491
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
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Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 46 bis 51 Tage
5.743,80 €
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HOST_Wheat germ Human Unkonjugiert   2 μg Anmelden zum Anzeigen 7 bis 8 Tage
406,59 €
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OPN1SW Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,

Mouse (Murine)

Weitere Proteine zu Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW) Interaktionspartnern

Zebrafish Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW) Interaktionspartner

  1. found a 0.3-kb region between 0.6 and 0.3 kb 5' of the SWS2 initiation codon, encompassing four cone-rod homeobox (zeige CRX Proteine)-binding sites (OTX sequences)

Guinea Pig Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW) Interaktionspartner

  1. Changes of opsin expression might play a role in the occurrence of experimental myopia in guinea pig.

Human Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW) Interaktionspartner

  1. LVAVA haplotype of the OPN1LW gene and MVAVA haplotype of the OPN1MW (zeige OPN1MW Proteine) gene cause apparently nonsyndromic high myopia in young patients but lead to progressive cone-rod dystrophy with deuteranopia and protanopia in middle-aged patients corresponding to a previously unknown disease course.

  2. Data suggest that insights into dimerization interface of red cone opsin should aid investigations of the structure and function of GPCR cell signaling.

  3. A novel homozygous PDE6C mutation was identified as the cause of ACHM. In addition, we identified an OPN1SW mutation in the sibling with complete achromatopsia.

  4. Individuals with the T190I S-opsin mutation behaved as mild tritans at 12.3-92.3Td, but as tritanopes at 1.2-9.2Td, for both light-adapted and dark-adapted conditions. The results are consistent with the mutant opsin causing abnormal S-cone function.

  5. A novel mutation(prolin/leucine) in the short-wavelength-sensitive cone pigment gene associated with a tritan color vision defect.

  6. 11-cis (zeige CISH Proteine)-retinol had no significant effect on the activity of human blue cone opsin

  7. Immunoreactivity to anti-OPN1SW antibodies was seen in the upper layer of human epidermis & reconstructed skin. The opsin mRNA was seen in total RNA from human skin. Neither immunoreactivity nor mRNA expression was seen in cultured human keratinocytes.

Mouse (Murine) Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW) Interaktionspartner

  1. quantitative FRET analysis in acutely isolated cone OS revealed that the cone degeneration-causing V268I mutation in peripherin-2 selectively reduced binding to M-opsin without affecting the peripherin-2 interaction to S-opsin or rhodopsin

  2. Deletion of one allele of S-opsin from Lrat (zeige LRAT Proteine)(-) (/-) mice (model of Leber congenital amaurosis) is sufficient to prevent rapid cone degeneration for at least 1 month. Deletion of both alleles of S-opsin prevents cone degeneration for at least 12 months.

  3. Thus, the three types of mouse opsin appear distinctive in the degree to which their bleached, unregenerated opsins generate "dark light."

  4. Opn1sw is a target gene for RORbeta (zeige RORB Proteine).

  5. TR beta (zeige TXNRD2 Proteine) 2 and S opsin are expressed in cone photoreceptors only. Both are transcribed by E13, and their levels increase with cone genesis.

OPN1SW Protein Überblick

Protein Überblick

This gene belongs to the G-protein coupled receptor 1 family, opsin subfamily. It encodes the blue cone pigment gene which is one of three types of cone photoreceptors responsible for normal color vision. Defects in this gene are the cause of tritan color blindness (tritanopia). Affected individuals lack blue and yellow sensory mechanisms while retaining those for red and green. Defective blue vision is characteristic.

Genbezeichner und Symbole assoziert mit OPN1SW

  • opsin 1 (cone pigments), short-wave-sensitive 2 (opn1sw2)
  • opsin 1 (cone pigments), short-wave-sensitive (OPN1SW)
  • blue-sensitive opsin (Blop)
  • KFH-B protein (kfh-b)
  • opsin 1 (cone pigments), short-wave-sensitive (opn1sw)
  • opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) (Opn1sw)
  • blue sensitive cone opsin (LOC396525)
  • opsin 1 (cone pigments), short-wave-sensitive (Opn1sw)
  • AW551857 Protein
  • Bcp Protein
  • Blop Protein
  • bluops Protein
  • BOP Protein
  • CBT Protein
  • CHK-2 Protein
  • GB13493 Protein
  • SI:zK13A21.5 (blue-sensitive opsin) Protein
  • SWS1 Protein
  • SWS2 Protein
  • zfblue Protein

Bezeichner auf Proteinebene für OPN1SW

opsin-1, short-wave-sensitive 2 , opsin SWS-2 , blue-sensitive opsin , blue cone photoreceptor pigment , blue-sensitive visual pigment opsin , opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) , SWS1 opsin , short-wave sensitive type 1 opsin , violet cone opsin , short-wave-sensitive (color blindness, tritan) , violet-sensitive visual pigment , opsin CHK-2 , short-wave-sensitive opsin 1 , BOP , blue cone opsin-like pigment , s opsin , short wavelength-sensitive cone opsin , cone pigment , blue opsin , Blue cone photoreceptor pigment , Blue-sensitive opsin , Short-wave-sensitive opsin 1 , S opsin , SWS opsin , UV cone pigment , blue cone opsin , blue cone pigment , blue/UV opsin , short wavelength sensitive opsin

GENE ID SPEZIES
30435 Danio rerio
397164 Sus scrofa
406128 Apis mellifera
752013 Taeniopygia guttata
100014924 Monodelphis domestica
100049179 Oryzias latipes
100125215 Xenopus (Silurana) tropicalis
100379279 Cavia porcellus
396525 Gallus gallus
611 Homo sapiens
81644 Rattus norvegicus
282294 Bos taurus
472508 Pan troglodytes
100994475 Pan paniscus
12057 Mus musculus
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