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N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. Zusätzlich bieten wir Ihnen NNMT Antikörper (111) und NNMT Kits (18) und viele weitere Produktgruppen zu diesem Protein an.
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this study provides the first demonstration that NNMT plays a role in the resistance to 5-fluorouracil in colorectal cancer cells
We suggest that lymph node metastatic adenoid cystic carcinoma (AdCC) cells acquire cancer stem cell features involving the up-regulation of NNMT and the loss of gap junction protein alpha-1 (zeige GJA1 Proteine), leading to epithelial-mesenchymal transition and consequent AdCC metastasis.
Progression of pulmonary hypertension is associated with the activation of the NNMT-1-methylnicotinamide pathway.
no SNP in NNMT is significantly associated with performance in 50-m run but rs2256292 is significantly associated with performance in 1000-m run in male Chinese college students
These findings indicate that the repression of NNMT may underlie nickel-induced H3K9 dimethylation by altering the cellular SAM (zeige TTN Proteine)/SAH (zeige ACSM3 Proteine) ratio.
NNMT expression is significantly upregulated in human masticatory mucosa during wound healing
The results show that a SNP (rs1941404) in NNMT is significantly associated with hyperlipidemia, and the influence of rs1941404 variation on the resting energy expenditure may be the possible mechanism for rs1941404 variation to induce hyperlipidemia.
NNMT gene rs694539 variant is a genetic risk factor for migraine in women.
There were no associations between MTHFR (zeige MTHFR Proteine) C677T, NNMT rs694539 AG/AA polymorphisms and conotruncal heart disease.
Data show that nicotinamide N-methyltransferase (NNMT) and the metabolic state regulate pluripotency in embryonic stem cells (hESCs).
Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide have been presented.
NNMT is a novel regulator of histone methylation, polyamine flux and NAD(+)-dependent SIRT1 (zeige SIRT1 Proteine) signalling, and is a unique and attractive target for treating obesity and type 2 diabetes
Brain NNMT expression was not altered in hyperhomocysteinemia.
Adipose tissue is a source of nicotinamide N-methyltransferase and homocysteine.
the progression of vascular inflammation and atherosclerosis was associated with the upregulation of hepatic nicotinamide N-methyltransferase activity and subsequent increase in endogenous MNA plasma levels
N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.
, nicotinamide n-methyltransferase
, Nicotinamide N-methyltransferase