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Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal NMBR Primary Antibody für WB - ABIN2787710
Matusiak, Glover, Nathaniel, Matkowskyj, Yang, Benya: Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon. in American journal of physiology. Gastrointestinal and liver physiology 2005
In sow estrous cycle, the hypothalamic levels of both NMB and NMBR mRAN were similar, but the expression levels of the pituitary were negatively correlated.
The rs2717 and rs6926279 within the NMBR gene were associated with schizophrenia liability.
Hypoxia regulates the expression of the neuromedin B receptor through a mechanism dependent on hypoxia-inducible factor-1alpha.
NMB and its receptor are coexpressed by proliferating cells in which they act in an autocrine fashion with similar and modest potency in both normal and malignant colonic epithelial cells.
NMB or NMBR silencing inhibited M-CSF (zeige CSF1R Antikörper)/c-Fms (zeige CSF1R Antikörper)-mediated downstream signaling pathways like activation of ERK (zeige EPHB2 Antikörper) and Akt (zeige AKT1 Antikörper) and induction of D-type cyclins, cyclin D1 (zeige CCND1 Antikörper) and D2.
mice with deletion of NB receptor have lower insulinemia, especially in response to oral glucose, and females also exhibited a better glucose tolerance, suggesting the involvement of neuromedin b and its receptor in regulation of insulin (zeige INS Antikörper) secretion induced by incretins, and also, in insulin (zeige INS Antikörper) sensitivity.
ablating NMB receptor-expressing neurons eliminated basal and hypoxia-induced sighing, but left breathing otherwise intact initially
The neuromedin B pathways are importantly involved in secretory pathways of TSH and revealed its participation in the in vivo regulation of gene expression of TSH beta (zeige TSHB Antikörper)-subunit (zeige POLG Antikörper) and pituitary MCT8 (zeige MCT8 Antikörper) and Thrb (zeige THRB Antikörper) and hypothalamic TRH (zeige TRH Antikörper) and type 2 deiodinase (zeige DIO2 Antikörper).
Together, we define the respective function of NMBR and GRPR (zeige GRPR Antikörper) in itch transmission, and reveal an unexpected relationship not only between the two receptors but also between the two populations of interneurons in itch signaling.
spinal GRPr (zeige GRPR Antikörper) and NMBr independently drive itch neurotransmission in mice.
Results implicate that NMB is involved in cartilage development, either in an autocrine or paracrine manner.
The data demonstrated that the neuromedin B-neuromedian B receptor interaction in pregnant myometrial primary cells in vitro predominantly influenced uterine activity through regulation of Il6 (zeige IL6 Antikörper) expression via the Rela/p65 (zeige NFkBP65 Antikörper) pathway.
These data demonstrate that neuromedin B and its receptor can induce the onset of labor via a RELA (zeige NFkBP65 Antikörper)/IL6 (zeige IL6 Antikörper)-mediated pathway.
The mRNA and protein expressions of NMBR reach a peak at the onset of labor.
Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue.
neuromedin B receptor
, neuromedin-B receptor
, epididymis tissue protein Li 185a
, neuromedin-B-preferring bombesin receptor