anti-Neurobeachin (NBEA) Antikörper

NBEA encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Zusätzlich bieten wir Ihnen Neurobeachin Kits (3) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NBEA 26422 Q9EPN1
NBEA 26960 Q8NFP9
NBEA 361948  
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Top anti-Neurobeachin Antikörper auf antikoerper-online.de

Showing 10 out of 38 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, IHC, WB ABIN188661 (1µg/ml) staining of 1) untransfected HEK293T cells 2) HEK293T cells transfected with mouse NBEA. Detected by chemiluminescence. Data kindly provided by Professor John Creemers, K.U. Leuven, Belgium 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Human Ziege Unkonjugiert ELISA, WB ABIN334444 (1µg/ml) staining of 1) untransfected HEK293T cells 2) HEK293T cells transfected with mouse NBEA. Detected by chemiluminescence. Data kindly provided by Professor John Creemers, K.U. Leuven, Belgium 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Rind (Kuh) Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$375.38
Details
Ratte Kaninchen Unkonjugiert ICC, IHC, WB dilution: 1 : 1000, sample: rat brain homogenate Indirect immunostaining of hippocampus neurons with anti-NBEA (dilution 1 : 1000; red) and mouse anti-PSD 95 (cat. no. 124 011, dilution 1 : 100; green). 50 μg Anmelden zum Anzeigen 5 bis 6 Tage
$398.48
Details
Ratte Meerschweinchen Unkonjugiert ICC, WB dilution: 1 : 1000, sample: rat brain homogenate Immunofluorescence labeling of cultured hippocampus neurons (dilution 1 : 1000; red). Synaptic terminals have been visualized by counterstaining with mouse anti-Synapsin (cat. no. 106 001, dilution 1 : 500; green). 100 μL Anmelden zum Anzeigen 5 bis 6 Tage
$358.05
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Fledermaus Ziege Unkonjugiert ELISA, IHC (p), WB   50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$595.83
Details
Rind (Kuh) Ziege Unkonjugiert ELISA, WB ABIN2564100 (1µg/ml) staining of 1) untransfected HEK293T cells 2) HEK293T cells transfected with mouse NBEA. Detected by chemiluminescence. 100 μL Anmelden zum Anzeigen 16 Days
$430.08
Details
Others Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Others Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

NBEA Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) ,
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Human , ,
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Rat (Rattus) ,
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Am meisten referenzierte anti-Neurobeachin Antikörper

  1. Rat (Rattus) Polyclonal Neurobeachin Primary Antibody für ICC, IHC - ABIN1742399 : Lauks, Klemmer, Farzana, Karupothula, Zalm, Cooke, Li, Smit, Toonen, Verhage: Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin. in PLoS ONE 2012 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal Neurobeachin Primary Antibody für ELISA, IHC - ABIN188661 : Wang, Herberg, Laue, Wullner, Hu, Petrasch-Parwez, Kilimann: Neurobeachin: A protein kinase A-anchoring, beige/Chediak-higashi protein homolog implicated in neuronal membrane traffic. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2001 (PubMed)

  3. Rat (Rattus) Polyclonal Neurobeachin Primary Antibody für ICC, WB - ABIN1742400 : Murray, Low, Swanson, Dieriks, Turner, Faull, Curtis: Distribution of PSA-NCAM in normal, Alzheimer's and Parkinson's disease human brain. in Neuroscience 2016 (PubMed)

Weitere Antikörper gegen Neurobeachin Interaktionspartner

Mouse (Murine) Neurobeachin (NBEA) Interaktionspartner

  1. Nbea targets glutamate (zeige GRIN1 Antikörper) and GABA receptors to the synapse via distinct molecular pathways by interacting with specific effector proteins.

  2. The physical interaction of NBEA with NOTCH1 (zeige NOTCH1 Antikörper) is most relevant for autism spectrum disorders pathogenesis because NOTCH (zeige NOTCH1 Antikörper) signaling is essential for neural development.

  3. These findings indicate that Nbea haploinsufficiency leads to various molecular and cellular changes that affect neuroplasticity and behavioral functions in mice

  4. Nbea regulates synaptic transmission under basal conditions by targeting neurotransmitter receptors to synapses.

  5. Synapse associated protein 102 (SAP102 (zeige DLG3 Antikörper)) binds the C-terminal part of the scaffolding protein neurobeachin.

  6. data obtained in mice and humans suggest that variation of Nbea abundance or activity critically affects body weight, presumably by influencing the activity of feeding-related neural circuits

  7. Data show that deletion of Nbea leads to reduced numbers of spinous synapses in cultured neurons from complete knockouts and in cortical tissue from heterozygous mice, accompanied by altered miniature postsynaptic currents.

  8. Nbea-null mice suffered block of evoked synaptic transmission at neuromuscular junctions, whereas nerve conduction, synaptic structure and synaptic vesicle release were normal supporting a neurotransmitter release role of Nbea at neuromuscular junctions

  9. Our data demonstrate for the first time a function of Nbea at central synapses that may be based on its presumed role in targeting membrane proteins to synaptic contacts.

Human Neurobeachin (NBEA) Interaktionspartner

  1. NBEA encodes neurobeachin: we found no evidence of association in data from the GWAS migraine meta-analysis consortium (n=118,710 participants) suggesting that the association might be specific to migraine co-morbid with bipolar disorder.

  2. Data indicate that the PVT1-NBEA and the PVT1-WWOX (zeige WWOX Antikörper) chimeric genes were associated with the expression of abnormal NBEA and WWOX (zeige WWOX Antikörper).

  3. Synapse associated protein 102 (SAP102 (zeige DLG3 Antikörper)) binds the C-terminal part of the scaffolding protein neurobeachin.

  4. data obtained in mice and humans suggest that variation of Nbea abundance or activity critically affects body weight, presumably by influencing the activity of feeding-related neural circuits

  5. neurobeachin encoding gene is disrupted in a patient with a de novo translocation t(5;13) (q12.1;q13.2), idiopathic autism, and no family history of autism

  6. The NBEA gene at 13q13, and its expression are frequently disrupted in MM.

Fruit Fly (Drosophila melanogaster) Neurobeachin (NBEA) Interaktionspartner

  1. This study demonistrated that functional homologies between Drosophila Rugose and mammalian NBEA that will help clarify the role of BEACH proteins in the development and function of the CNS in vivo.

  2. Drosophila spoonbill encodes a dual-specificity A-kinase anchor protein (zeige CELSR3 Antikörper) essential for oogenesis.

  3. results suggest that rg is required for correct retinal pattern formation and may function in cell fate determination through its interactions with the EGFR (zeige EGFR Antikörper) and Notch (zeige NOTCH1 Antikörper) signaling pathways

  4. results suggest that rugose gene encodes a secondary pigment cell specific function, and plays an essential role in determining the optic lobe's structure

  5. Rugose (rg) plays an important role in the integration of different signals required for the exact regulation of cone cell development and survival.

Zebrafish Neurobeachin (NBEA) Interaktionspartner

Neurobeachin (NBEA) Antigen-Profil

Protein Überblick

This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.

Genbezeichner und Symbole assoziert mit anti-Neurobeachin (NBEA) Antikörper

  • neurobeachin (Nbea) Antikörper
  • neurobeachin (NBEA) Antikörper
  • neurobeachin (LOC5565116) Antikörper
  • neurobeachin (CpipJ_CPIJ007145) Antikörper
  • rugose (rg) Antikörper
  • neurobeachin a (nbeaa) Antikörper
  • AKAP Antikörper
  • Akap550 Antikörper
  • BCL8B Antikörper
  • CG6775 Antikörper
  • CG15466 Antikörper
  • DAKAP550 Antikörper
  • Dmel\\CG6775 Antikörper
  • fas Antikörper
  • im:7138260 Antikörper
  • LYST2 Antikörper
  • mKIAA1544 Antikörper
  • nbea Antikörper
  • RGD1562629 Antikörper
  • si:ch211-125n11.1 Antikörper
  • zgc:113510 Antikörper

Bezeichner auf Proteinebene für anti-Neurobeachin (NBEA) Antikörper

lysosomal trafficking regulator 2 , lysosomal-trafficking regulator 2 , neurobeachin , A kinase anchor protein 550 , CG6775-PB , CG6775-PC , CG6775-PD , CG6775-PE , CG6775-PF , drosophila A kinase anchor protein , facetious , pebbled , rg-PB , rg-PC , rg-PD , rg-PE , rg-PF , LOW QUALITY PROTEIN: neurobeachin

GENE ID SPEZIES
26422 Mus musculus
26960 Homo sapiens
5565116 Aedes aegypti
6039024 Culex quinquefasciatus
477305 Canis lupus familiaris
525624 Bos taurus
44531 Drosophila melanogaster
395195 Gallus gallus
361948 Rattus norvegicus
541373 Danio rerio
100715352 Cavia porcellus
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