Myocilin (MYOC) ELISA Kits

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. Zusätzlich bieten wir Ihnen Myocilin Antikörper (62) und Myocilin Proteine (23) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus MYOC MYOC 17926 O70624
MYOC 4653 Q99972
Anti-Ratte MYOC MYOC 81523 Q9R1J4
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.039 U/mL 0.156-10 U/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
772,39 €
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Weitere ELISA Kits für Myocilin Interaktionspartner

Mouse (Murine) Myocilin (MYOC) Interaktionspartner

  1. mutant myocilin induces abnormal ECM (zeige MMRN1 ELISA Kits) accumulation in the ER of TM cells, which may be responsible for reduced outflow facility and IOP elevation in myocilin-associated glaucoma.

  2. Mutated myocilin and heterozygous Sod2 (zeige SOD2 ELISA Kits) deficiency act synergistically in a mouse model of open-angle glaucoma

  3. myocilin promotes cell proliferation and resistance to apoptosis via the ERK1/2 (zeige MAPK1/3 ELISA Kits) MAPK (zeige MAPK1 ELISA Kits) signaling pathway.

  4. Myocilin binds to ErbB2 (zeige ERBB2 ELISA Kits)/ErbB3 (zeige ERBB3 ELISA Kits), activates these receptors, and affects the downstream PI3K-AKT (zeige AKT1 ELISA Kits) signaling pathway

  5. Myocilin also stimulated osteogenic differentiation of wild-type MSCs, which was associated with activation of the p38 (zeige CRK ELISA Kits), Erk1/2 (zeige MAPK1/3 ELISA Kits), and JNK (zeige MAPK8 ELISA Kits) MAP kinase (zeige MAPK1 ELISA Kits) signaling pathways

  6. We suggest that intracellular myocilin plays a role as a regulator of muscle hypertrophy pathways, acting through the components of dystrophin (zeige DMD ELISA Kits) associated protein complex.

  7. The TIGR is implicated in resistance to oxidative stress. Despite the presence of a SOD motif, which is necessary for protection in mammalian cells, the protein is not a functional SOD, but might be involved in SOD activity.

  8. TIGR is a newly identified component of the CNS glial scar that is likely to contribute to neuronal regenerative failure characteristic of the mammalian CNS.

  9. Results do not support a causative role for increased MYOC levels or the MYOC gene in steroid-induced glaucoma.

  10. Results show that myocilin and gamma-synuclein (zeige SNCG PLURAL_@30212@) interact and as a result, myocilin's properties are changed.

Human Myocilin (MYOC) Interaktionspartner

  1. The four detected MYOC mutations appeared to be associated with morphologic changes in the trabecular meshwork and the underlying pathogenesis of a subtype of familial primary open angle glaucoma.

  2. The mutations c.1456C < T (p.L486F) in MYOC and c.322G < A (p.V108I) in B4GALT3 (zeige B4GALT3 ELISA Kits) are likely responsible for the pathogenesis of Primary Open-angle Glaucoma in this family.

  3. Our findings demonstrated that MYOC cascade genetic testing for POAG allows identification of at-risk individuals at an early stage or even before signs of glaucoma are present. To our knowledge, this is the first study to demonstrate the clinical utility of predictive genetic testing for MYOC glaucoma.

  4. regulation by retinoic acid acts through the MYOC promoter which contains a critical cluster of four retinoic acid responsive (zeige GPRC5A ELISA Kits) elements (RAREs), with the RARE-DR2 presenting the strongest effect and binding the RARalpha (zeige RARA ELISA Kits)/RXRalpha (zeige RXRA ELISA Kits) heterodimer.

  5. Five out of 30 families with PCG (16.7%) had disease attributable to CYP1B1 (zeige CYP1B1 ELISA Kits) alterations suggesting that CYP1B1 (zeige CYP1B1 ELISA Kits) is not the major gene causing PCG in Vietnamese unlike in the case of Arab or Romany patients.

  6. The present study provides insight into the genetic or haplotype variants of MYOC and OPTN (zeige OPTN ELISA Kits) genes contributing to primary glaucoma. Haplotype variants identified in the present study may be regarded as potential contributing factors of primary glaucoma in Korea.

  7. Familial linkage studies for primary angle-closure glaucoma have been performed and identified MYOC causative primary angle-closure glaucoma disease

  8. The rate of CYP1B1 (zeige CYP1B1 ELISA Kits) mutations in Lebanese patients with primary congenital glaucoma (PCG) is lower than that reported in other Arab and Middle Eastern populations and suggests other genes are responsible.

  9. Data show that predictive genetic testing for early onset Myocilin glaucoma can facilitate early detection of disease or discharge from routine ophthalmic examinations.

  10. This study does not confirm a role for genetic variants in the MYOC, NR3C1 (zeige NR3C1 ELISA Kits) and FKBP5 (zeige FKBP5 ELISA Kits) genes in the pathogenesis of corticosteroid-induced ocular hypertension.

Cow (Bovine) Myocilin (MYOC) Interaktionspartner

  1. endoproteolytic processing might regulate the activity of myocilin; the inhibition of the processing by pathogenic mutations impairs the normal role of myocilin

Myocilin (MYOC) Antigen-Profil

Beschreibung des Gens

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Genbezeichner und Symbole assoziert mit Myocilin (MYOC) ELISA Kits

  • myocilin (MYOC) Antikörper
  • myocilin (myoc) Antikörper
  • myocilin (Myoc) Antikörper
  • myocilin, trabecular meshwork inducible glucocorticoid response (MYOC) Antikörper
  • myocilin, trabecular meshwork inducible glucocorticoid response (Myoc) Antikörper
  • AI957332 Antikörper
  • GLC1A Antikörper
  • GPOA Antikörper
  • JOAG Antikörper
  • JOAG1 Antikörper
  • MGC136645 Antikörper
  • MYOC Antikörper
  • myocilin Antikörper
  • Tigr Antikörper
  • zgc:136645 Antikörper

Bezeichner auf Proteinebene für Myocilin (MYOC) ELISA Kits

myocilin , trabecular meshwork-induced glucocorticoid response protein , mutated trabecular meshwork-induced glucocorticoid response protein

GENE ID SPEZIES
397046 Sus scrofa
548602 Danio rerio
704406 Macaca mulatta
17926 Mus musculus
4653 Homo sapiens
81523 Rattus norvegicus
281342 Bos taurus
101087632 Felis catus
490344 Canis lupus familiaris
100008897 Oryctolagus cuniculus
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