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Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. Zusätzlich bieten wir Ihnen Multimerin 1 Kits (20) und Multimerin 1 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal Multimerin 1 Primary Antibody für IHC, IHC (p) - ABIN4335131
Mizrachi Nebenzahl, Blau, Kushnir, Shagan, Portnoi, Cohen, Azriel, Malka, Adawi, Kafka, Dotan, Guterman, Troib, Fishilevich, Gershoni, Braiman, Mitchell, Mitchell, Porat, Goliand, Chalifa Caspi et al.: Streptococcus pneumoniae Cell-Wall-Localized Phosphoenolpyruvate Protein Phosphotransferase Can Function as an Adhesin: Identification of Its Host Target Molecules and Evaluation of Its Potential as ... in PLoS ONE 2016
Our data suggest that multimerin 1 supports platelet adhesive functions and thrombus formation, which will be important to verify by generating and testing selective multimerin 1 deficient mice.
Lower levels of anti-elastin (zeige ELN Antikörper) are related to CAD (zeige CAD Antikörper) [ coronary artery disease ]
our studies identify MMRN1 expression as a novel biomarker that may refine acute myelogenous leukemia risk stratification.
multimerin 1 has a role in delivering and localizing factor V onto platelets prior to prothrombinase (zeige F10 Antikörper) assembly
disulfide-linked complexes of multimerin and factor V in platelets could be important for modulating the function of platelet factor V and its delivery onto activated platelets
MMRN1 is a ligand for alphaIIbbeta3 and alphavbeta3
The MMRN1 binding site was located in Factor V.
Multimerin 1 binds factor V and activated factor V with high affinity and inhibits thrombin (zeige F2 Antikörper) generation.
MMRN1 supported the adhesion of activated, but not resting, washed platelets over a wide range of shear rates
Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin.
, elastin microfibril interface located protein 4
, elastin microfibril interfacer 4
, endothelial cell multimerin
, glycoprotein Ia*