Matrix Metallopeptidase 8 (Neutrophil Collagenase) Proteine (MMP8)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Zusätzlich bieten wir Ihnen MMP8 Antikörper (179) und MMP8 Kits (92) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MMP8 17394 O70138
MMP8 63849 O88766
MMP8 4317 P22894
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Top MMP8 Proteine auf antikoerper-online.de

Showing 10 out of 25 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Human Cells Human His tag 10 μg Anmelden zum Anzeigen 18 bis 20 Tage
287,50 €
Details
HOST_CHO Cells Maus His tag 10 μg Anmelden zum Anzeigen 18 bis 20 Tage
287,50 €
Details
HOST_Human Cells Maus Unkonjugiert 10 μg Anmelden zum Anzeigen 18 bis 20 Tage
287,50 €
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_HEK-293 Human Unkonjugiert   10 μg Anmelden zum Anzeigen 6 bis 8 Tage
196,71 €
Details
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_Escherichia coli (E. coli) Ratte His tag,T7 tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
685,71 €
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HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 7 bis 8 Tage
235,20 €
Details
HOST_Human Human Unkonjugiert 5 μg Anmelden zum Anzeigen 6 bis 8 Tage
279,36 €
Details
HOST_Escherichia coli (E. coli) Human His tag   1 U Anmelden zum Anzeigen 6 bis 8 Tage
218,50 €
Details

MMP8 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) , ,

Rat (Rattus) ,
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Human , , , ,
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Am meisten referenzierte MMP8 Proteine

  1. Human MMP8 Protein expressed in HEK-293 - ABIN2666511 : Fang, Wen, Zhang, Lin, Moore, Wu, Ye, Xiao: An important role of matrix metalloproteinase-8 in angiogenesis in vitro and in vivo. in Cardiovascular research 2013 (PubMed)
    Zeige alle 6 Referenzen für 2666511

  2. Human MMP8 Protein expressed in Human Cells - ABIN2002436 : Belotti, Paganoni, Manenti, Garofalo, Marchini, Taraboletti, Giavazzi: Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: implications for ascites formation. in Cancer research 2003 (PubMed)
    Zeige alle 3 Referenzen für 2002436

  3. Mouse (Murine) MMP8 Protein expressed in Human Cells - ABIN2007891 : Mira, Lacalle, Buesa, de Buitrago, Jiménez-Baranda, Gómez-Moutón, Martínez-A, Mañes: Secreted MMP9 promotes angiogenesis more efficiently than constitutive active MMP9 bound to the tumor cell surface. in Journal of cell science 2004 (PubMed)
    Zeige alle 3 Referenzen für 2007891

  4. Mouse (Murine) MMP8 Protein expressed in CHO Cells - ABIN2007889 : Ram, Sherer, Shoenfeld: Matrix metalloproteinase-9 and autoimmune diseases. in Journal of clinical immunology 2006 (PubMed)
    Zeige alle 3 Referenzen für 2007889

Weitere Proteine zu Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) Interaktionspartnern

Mouse (Murine) Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) Interaktionspartner

  1. MMP8 plays an important role in intestinal I/R injury through mechanisms involving increased inflammation and loss of claudin-3 (zeige CLDN3 Proteine)

  2. These results suggest that some of the anti-inflammatory effects of Dexamethasone are mediated through increased MMP-8 expression.

  3. These results suggest a novel pathogenetic role of MMP8 and implicate modulation of its activity as a tractable strategy for therapies against cerebral ischemia.

  4. Fusion peptide inhibitors of MMP-8/-9 prevent endotoxic shock if administered within a strict time window.

  5. the loss of MMP-8 likely has pleiotropic effects on innate immunity and angiogenesis that are reflected in changes in the protease web.

  6. A previously unknown role of MMP8 in M2-macrophage polarization by cleaving fibromodulin (zeige FMOD Proteine) and therefore increasing the bioavailability of TGF-beta (zeige TGFB1 Proteine).

  7. MMP-8-deficient mice had significantly lower serum triglyceride (TG) levels (P = 0.003) and larger HDL (zeige HSD11B1 Proteine) particles compared with wild-type (WT) mice. However, no differences were observed in the apoA-I (zeige APOA1 Proteine) levels.

  8. These results demonstrate that MMP-8 critically mediates microglial activation by modulating TNF-alpha (zeige TNF Proteine) activity, which may explain neuroinflammation in septic mouse brain.

  9. MMP-13 (zeige MMP13 Proteine) prevails over MMP-8 in collagen degradation in atheromata.

  10. MMP8 enhances vascular smooth muscle cell proliferation via an ADAM10 (zeige ADAM10 Proteine), N-cadherin (zeige CDH2 Proteine), and beta-catenin (zeige CTNNB1 Proteine)-mediated pathway and plays an important role in neointima formation.

Human Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) Interaktionspartner

  1. These results provide the first evidence that MMP8 SNP at the rs11225394 locus is associated with the increased risk of osteonecrosis of the femoral head in Chinese Han population.

  2. Low MMP-8/TIMP-1 (zeige TIMP1 Proteine) reflects left ventricle impairment in takotsubo cardiomyopathy and high TIMP-1 (zeige TIMP1 Proteine) may help to differentiate it from acute coronary syndrome

  3. Plasma levels of MMP-1 (zeige MMP1 Proteine), MMP-8, and MMP-9 (zeige MMP9 Proteine) are associated with COPD (zeige ARCN1 Proteine) severity and can be used as a biomarker to better understand the characteristics of COPD (zeige ARCN1 Proteine) patients.

  4. there is a negative correlation between blood MMP8 and HDL (zeige HSD11B1 Proteine)-cholesterol levels, suggesting a contributory role of MMP8 in metabolic alterations in acne inversa

  5. plasma concentrations of MMP-7 (zeige MMP7 Proteine), MMP-8, -9 and TIMP-1 (zeige TIMP1 Proteine) within 96 h from the onset of acute pancreatitis symptoms are elevated in acute pancreatitis patients compared with healthy controls

  6. MMP-8 is a vital component of the myoepithelial tumour-suppressor function. It restores MEC (zeige CCL28 Proteine) interaction with the matrix, opposes TGF-beta (zeige TGFB1 Proteine) signalling and MMP-9 (zeige MMP9 Proteine) proteolysis, which contributes to inhibition of tumour cell invasion.

  7. a 7-gene signature was identified which correctly predicted the primary prefibrotic myelofibrosis group with a sensitivity of 100% and a specificity of 89%. The 7 genes included MPO (zeige MPO Proteine), CEACAM8, CRISP3 (zeige CRISP3 Proteine), MS4A3 (zeige MS4A3 Proteine), CEACAM6, HEMGN, and MMP8

  8. Obesity is associated with elevated circulating MMP-8 in young adults. MMP-8 is also increased in smokers.

  9. infiltrative pulmonary tuberculosis is characterized by impairements in the system MMP/inhibitors: the levels of MMP-1 (zeige MMP1 Proteine), -9 increased, MMP-3 (zeige MMP3 Proteine), -8, TIMP-1 (zeige TIMP1 Proteine) remained at the reference values and a 2-macroglobulin was low.

  10. Serum level patterns of MMP-2 (zeige MMP2 Proteine) and MMP-8 showed distinctive patterns for patients with spinal cord injury neurological impairment. MMP-8 and MMP-9 (zeige MMP9 Proteine) patterns showed significant differences regarding functional recovery. Our binary logistic regression model showed that, according to neurological damage, measuring peripheral serum levels can be used to monitor and predict locomotor recovery after spinal cord injury.

MMP8 Protein Überblick

Protein Überblick

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Genbezeichner und Symbole assoziert mit MMP8

  • matrix metallopeptidase 8 (neutrophil collagenase) (MMP8)
  • matrix metallopeptidase 8 (Mmp8)
  • matrix metallopeptidase 8 (neutrophil collagenase) (Mmp8)
  • matrix metalloproteinase 8 (LOC100339790)
  • BB138268 Protein
  • CLG1 Protein
  • HNC Protein
  • MMP-8 Protein
  • MMP8 Protein
  • PMNL-CL Protein

Bezeichner auf Proteinebene für MMP8

matrix metallopeptidase 8 (neutrophil collagenase) , matrix metalloproteinase 8 , MMP-8 , collagenase 2 , collagenase-2 , matrix metalloproteinase-8 , neutrophil collagenase , neutrophil collagenease , PMNL collagenase , matrix metalloproteinase 8 (neutrophil collagenase)

GENE ID SPEZIES
740516 Pan troglodytes
17394 Mus musculus
63849 Rattus norvegicus
4317 Homo sapiens
100724670 Cavia porcellus
100339790 Oryctolagus cuniculus
Ausgewählte Anbieter für MMP8 Proteine (MMP8)
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