anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Antikörper

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Zusätzlich bieten wir Ihnen Matrix Metallopeptidase 13 (Collagenase 3) Kits (144) und Matrix Metallopeptidase 13 (Collagenase 3) Proteine (41) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MMP13 4322 P45452
MMP13 17386 P33435
MMP13 171052  
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Top anti-Matrix Metallopeptidase 13 (Collagenase 3) Antikörper auf antikoerper-online.de

Showing 10 out of 290 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-MMP13 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Placenta <b>Sample Type:</b> Equine Cartilage Explants <br> <b>Primary Dilution: </b>1:1000 <br> <b>Secondary Antibody:</b> Bio-Rad 170-5046 <br><b>Secondary Dilution: </b>1:100,000<br><b>Image Submitted By:</b> Adam Williams<br>University of Nottingham 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat articular cartilage labeled with Anti-MMP-13 Polyclonal Antibody (ABIN670341), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining Generously provided by Markus Linder from Medical University Vienna as part of the Bioss Discovery Program. Formalin-fixed, paraffin embedded, and decalcified in EDTA mouse bone labeled with Anti-MMP-13 Polyclonal Antibody, Unconjugated (ABIN670341) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$307.45
Details
Rind (Kuh) Kaninchen Unkonjugiert IP, IHC, WB Western blot analysis of MMP-13 expression with Jurkat cell lysate. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$285.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of MMP13(arrow) using rabbit polyclonal MMP13 Antibody (ABIN390137). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the MMP13 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from LOVO cells, using MMP-13 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MMP-13 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB The MMP-13 Antibody is used in Western blot to detect MMP-13 1 in rat lung. 0.1 mg Anmelden zum Anzeigen 2 bis 6 Tage
$327.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: MMP13 Antibody [NBP2-17310] - Sample (30 ug of whole cell lysate) A: NT2D1 10% SDS PAGE gel, diluted at 1:1000. Immunocytochemistry/Immunofluorescence: MMP-13 Antibody [NBP2-17310] - NT2D1 cells were fixed in ice-cold MeOH for 5 min. Green: MMP13 protein stained by MMP13 antibody [N3C1], Internal diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details
Rind (Kuh) Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, SimWes, WB Immunocytochemistry/Immunofluorescence: MMP-13 Antibody [NBP1-45723] - MMP-13 antibody was tested at 1:50 in MDA-MB-231 cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Image objective 40x. Western Blot: MMP-13 Antibody [NBP1-45723] - Analysis of MMP-13 in human full-length recombinant protein using anti-MMP-13 antibody. Image from verified customer review. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$389.81
Details

MMP13 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-Matrix Metallopeptidase 13 (Collagenase 3) Antikörper

  1. Human Polyclonal MMP13 Primary Antibody für IF (p), IHC (p) - ABIN670341 : Luo, Zhang, Wang, Hu, Song, Su, Zhang: Alendronate retards the progression of lumbar intervertebral disc degeneration in ovariectomized rats. in Bone 2013 (PubMed)
    Show all 4 Pubmed References

  2. Cow (Bovine) Polyclonal MMP13 Primary Antibody für IP, IHC - ABIN223238 : Spinale, Escobar, Mukherjee, Zavadzkas, Saunders, Jeffords, Leone, Beck, Bouges, Stroud: Cardiac-restricted overexpression of membrane type-1 matrix metalloproteinase in mice: effects on myocardial remodeling with aging. in Circulation. Heart failure 2009 (PubMed)
    Show all 2 Pubmed References

  3. Rat (Rattus) Polyclonal MMP13 Primary Antibody für ICC, IHC - ABIN1172288 : Chu, Dai, Wang, Tian, Song, Xiao, Shao, Zhang, Zhang: Strontium ranelate causes osteophytes overgrowth in a model of early phase osteoarthritis. in BMC musculoskeletal disorders 2017 (PubMed)

  4. Cow (Bovine) Polyclonal MMP13 Primary Antibody für WB - ABIN2786656 : Borghese, Chiche, Vernerey, Chenot, Mir, Bijaoui, Bonaiti-Pellié, Chapron: Genetic polymorphisms of matrix metalloproteinase 12 and 13 genes are implicated in endometriosis progression. in Human reproduction (Oxford, England) 2008 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal MMP13 Primary Antibody für ICC, IF - ABIN4334943 : Huang, Ao, Li, Wu, Xu, Deng, Chen, Yin, Cheng: Autophagy Protects Advanced Glycation End Product-Induced Apoptosis and Expression of MMP-3 and MMP-13 in Rat Chondrocytes. in BioMed research international 2017 (PubMed)

  6. Cow (Bovine) Polyclonal MMP13 Primary Antibody für ICC, IF - ABIN4334942 : Ma, Liu, Wang, Chen, Liu, Li, Xiang, Wei, Duan, Han: Tamoxifen induces the development of hernia in mice by activating MMP-2 and MMP-13 expression. in Biochimica et biophysica acta 2015 (PubMed)

Weitere Antikörper gegen Matrix Metallopeptidase 13 (Collagenase 3) Interaktionspartner

Zebrafish Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. MeHg impairs tail development at least partially by activation of the tissue remodeling proteases Mmp9 (zeige MMP9 Antikörper) and Mmp13.

  2. Zebra fish embryogenesis requires MMP-13 and dexamethasone and hydrocortisone modulate the expression of this gene, leading to increased activity and potentially contributing to subsequent dysmorphogenesis.

  3. JNK (zeige MAPK8 Antikörper)-Mmp13 signaling pathway plays an essential role in regulating the innate immune cell migration in response to severe injury in vivo

Xenopus laevis Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. XCL3 and XCL4 can be differentially induced by prolactin (zeige PRL Antikörper) and thyroid hormone (zeige PTH Antikörper)(3)

Mouse (Murine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. data reveal a novel involvement of MMP-13 in regulating dendritic cell (DC) immunobiology through moderating MHC-I surface presentation, endocytosis and cytokine/chemokine (zeige CCL1 Antikörper) secretion; furthermore, the reduced MHC-I surface presentation by DCs resulted in a poor CD8 (zeige CD8A Antikörper)(+) T-cell response in vitro; MMP-13 might be a promising target for therapeutic intervention in inflammatory diseases

  2. The progressive process of articular cartilage degeneration was significantly delayed in the knee joints of Ddr2 (zeige DDR2 Antikörper)-deficient mice in comparison to their control littermates. Articular cartilage damage in the knee joints of the mice was associated with increased expression profiles of both Ddr2 (zeige DDR2 Antikörper) and matrix metalloproteinase 13.

  3. Postnatal chondrocyte-specific deletion of Hdac3 (zeige HDAC3 Antikörper) with an inducible Col2a1 (zeige COL2A1 Antikörper)-Cre caused premature production of pErk1/2 and Mmp13 in the growth plate.

  4. Mmp13 is selectively regulated of by 1,25-Dihydroxyvitamin D3, PTH (zeige PTH Antikörper), and Osterix (zeige SP7 Antikörper) through distal enhancers.

  5. Our study contributes to the understanding of the role of HIF1alpha (zeige HIF1A Antikörper) in OA and highlights the HIF1alpha (zeige HIF1A Antikörper)-beta-catenin (zeige CTNNB1 Antikörper) interaction, thus providing new insights into the impact of hypoxia in articular cartilage.

  6. Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1 (zeige MMP1 Antikörper)/protease-activated receptor-1 (zeige F2R Antikörper) axis may play a role in neurogenesis following physiological and/or pathological stimuli.

  7. IL-1Ra (zeige IL1RN Antikörper) is associated with MMP-13 expression and has a novel function in such regulation without interference of the IL-1 (zeige IL1A Antikörper) signaling cascade.

  8. We reveal a novel role of AP-2epsilon in the regulation of gene expression in articular chondrocytes, as well as in osteoarthritis development, through modulation of Mmp13 expression and activity.

  9. B-16 melanoma cells with up-regulated MMP-13 expression promoted invasion of tumor cells through Matrigel compared with control cells transfected with empty vector. Knocked-down MMP-13 expression also decreased invading cell numbers.

  10. MMP-12 (zeige MMP12 Antikörper) and MMP-13 alter strain K infection in mice and play a role in inflammatory regulation by modulating cytokine levels.

Human Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. IL-11 (zeige IL11 Antikörper) induces the expression of MMP-13 in gastric cancer SCH (zeige NF2 Antikörper) cells partly via the PI3K (zeige PIK3CA Antikörper)-AKT (zeige AKT1 Antikörper) and JAK (zeige JAK3 Antikörper)-STAT3 (zeige STAT3 Antikörper) pathways.

  2. Our findings suggest significant association for MMP-13 rs2252070 A>G to increased susceptibility to human cancer

  3. IL-6 (zeige IL6 Antikörper)-stimulated MMP-13 expression was independent of IL-1beta (zeige IL1B Antikörper) stimulation and was blocked by SAHA, suggesting that SAHA inhibits IL-6 (zeige IL6 Antikörper) signaling in Osteoarthritis (OA) chondrocytes.

  4. High MMP13 expression is associated with intervertebral disc degeneration.

  5. data demonstrate that MMP-13 is critical for the development of osteolytic lesions in Multiple myeloma and that targeting the MMP-13 protein - rather than its catalytic activity - constitutes a potential approach to mitigating bone disease in affected patients.

  6. Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritic chondrocytes, which manifested in increased expression of ADAMTS5 (zeige ADAMTS5 Antikörper), MMP13, and decreased COL2A1 (zeige COL2A1 Antikörper) expression.

  7. Matrix metalloprotease (MMP) regulation was the top pathway involved in gingival aging. MMP3 (zeige MMP3 Antikörper), MMP9 (zeige MMP9 Antikörper), MMP12 (zeige MMP12 Antikörper), and MMP13 were upregulated in old gingival tissues, concomitantly with interleukin-1 beta (IL1B (zeige IL1B Antikörper)) expression.

  8. these findings support roles for both cFOS (indirect) and ATF3 (zeige ATF3 Antikörper) (direct) in effecting MMP13 transcription in human chondrocytes.

  9. Oxytocin prevents cartilage matrix destruction via regulating MMP1 (zeige MMP1 Antikörper) and MMP13.

  10. These studies have uncovered a new, ATP6V1H (zeige ATP6V1H Antikörper)-mediated pathway that regulates bone formation, and defines a new mechanism of disease that leads to bone loss. We propose that MMP9 (zeige MMP9 Antikörper)/MMP13 could be therapeutic targets for patients with this rare genetic disease.

Horse (Equine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. The DNA microarray analysis for matrix metalloproteinase (MMP)-related mRNA expression in equine superficial digital flexor tendinitis indicated that mRNA level of MMP-13 was apparently up-regulated in the tendinitis as compared to normal tendon.

Cow (Bovine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. p38 (zeige MAPK14 Antikörper) phosphorylation and MMP13 expression are regulated by Rho/ROCK activation, and support the potential novel pathway that Rho/ROCK is in the upper part of the mechanical stress-induced matrix degeneration cascade in cartilage.

  2. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.

  3. MMP-13 treatment of fresh articular cartilage results in cleaved fibromodulin (zeige FMOD Antikörper) fragments

  4. increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 (zeige MMP1 Antikörper) and MMP-13 (follicular apex (zeige APEX1 Antikörper) vs. base) for the preovulatory collagenolysis required for follicle rupture

  5. involvement of p38 MAP kinase (zeige MAPK14 Antikörper) in the hyaluronan oligosaccharide induction of MMP-13

  6. MMP-13 and collagenase have roles in chondrocyte hypertrophy induced by type II collagen (zeige COL2A1 Antikörper)

  7. At high but naturally occurring concentrations the collagen peptide CB12 (zeige PABPC4 Antikörper)-II induced an increase in the expressions of MMP-13 and cleavage of type II collagen (zeige COL2A1 Antikörper) by collagenase in the mid zone and also in the superficial zone.

Rabbit Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. These results suggest that PEP-1-SIRT2 (zeige SIRT2 Antikörper) promotes matrix metalloproteinases-induced dedifferentiation via ERK (zeige MAPK1 Antikörper) signaling in articular chondrocytes.

  2. chitosan-pDNA nanoparticles encoding shRNA targeting MMP-3 (zeige MMP3 Antikörper) and -13 had great potential in silencing the dedifferentiation-related genes for regenerating prolonged and endurable cartilage.

  3. Leptin (zeige LEP Antikörper) can induce MMP-13 and have a synergistic induction effect on NO with TNF-alpha (zeige TNF Antikörper) in rabbit articular chondrocytes in vitro.

Pig (Porcine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. TNF-alpha (zeige TNF Antikörper) induced MMP-13 expression by condylar cells might be involved in the degradation of the juvenile condyle.

Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Antigen-Profil

Protein Überblick

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Genbezeichner und Symbole assoziert mit MMP13

  • matrix metallopeptidase 13 (MMP13) Antikörper
  • matrix metallopeptidase 13 (Mmp13) Antikörper
  • matrix metalloproteinase 7 (MGC68994) Antikörper
  • matrix metallopeptidase 13a (mmp13a) Antikörper
  • matrix metallopeptidase 13 (collagenase 3) like S homeolog (mmp13l.S) Antikörper
  • matrix metallopeptidase 13 (collagenase 3) (mmp13) Antikörper
  • matrix metalloproteinase 13 (LOC100136348) Antikörper
  • matrix metallopeptidase 12 (MMP12) Antikörper
  • matrix metalloproteinase 13 (mmp13) Antikörper
  • matrix metallopeptidase 13 (mmp13) Antikörper
  • matrix metallopeptidase 13 (collagenase 3) like L homeolog (mmp13l.L) Antikörper
  • cb1034 Antikörper
  • Clg Antikörper
  • CLG3 Antikörper
  • gene A Antikörper
  • MANDP1 Antikörper
  • MGC108008 Antikörper
  • MMP-13 Antikörper
  • Mmp1 Antikörper
  • MMP13 Antikörper
  • xcl3 Antikörper
  • xCol Antikörper

Bezeichner auf Proteinebene für MMP13

MMP-13 , collagenase 3 , matrix metalloproteinase 13 (collagenase 3) , Collagenase-3 , collagenase-1 , interstitial collagenase , matrix metalloproteinase 13 , matrix metalloproteinase-13 , UMRCASE , collagenase-3 , MMPLg , MMPLh , gene 11 , matrix metallopeptidase 13 (collagenase 3) , gene A , collagenase 3-like

GENE ID SPEZIES
4322 Homo sapiens
17386 Mus musculus
171052 Rattus norvegicus
281914 Bos taurus
379552 Xenopus laevis
387293 Danio rerio
398056 Xenopus laevis
443113 Ovis aries
451513 Pan troglodytes
493679 Felis catus
613098 Xenopus (Silurana) tropicalis
703980 Macaca mulatta
100008685 Oryctolagus cuniculus
100009711 Equus caballus
100012553 Monodelphis domestica
100136348 Salmo salar
100396943 Callithrix jacchus
100462632 Pongo abelii
100526826 Ictalurus punctatus
100552256 Anolis carolinensis
100584961 Nomascus leucogenys
397346 Sus scrofa
397823 Xenopus laevis
395683 Gallus gallus
403763 Canis lupus familiaris
100731756 Cavia porcellus
Ausgewählte Anbieter für anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Antikörper
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