anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Antikörper

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as art. Zusätzlich bieten wir Ihnen Matrix Metallopeptidase 13 (Collagenase 3) Kits (123) und Matrix Metallopeptidase 13 (Collagenase 3) Proteine (49) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MMP13 17386 P33435
MMP13 171052  
MMP13 4322 P45452
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Top anti-Matrix Metallopeptidase 13 (Collagenase 3) Antikörper auf antikoerper-online.de

Showing 10 out of 287 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-MMP13 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Placenta Sample Type: Equine Cartilage Explants  Primary Dilution: 1:1000  Secondary Antibody: Bio-Rad 170-5046 Secondary Dilution: 1:100,000Image Submitted By: Adam WilliamsUniversity of Nottingham 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Maus Unkonjugiert IHC (p), IP 0.5 mL Anmelden zum Anzeigen 7 bis 9 Tage
528,00 €
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat articular cartilage labeled with Anti-MMP-13 Polyclonal Antibody (ABIN670341), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining Generously provided by Markus Linder from Medical University Vienna as part of the Bioss Discovery Program. Formalin-fixed, paraffin embedded, and decalcified in EDTA mouse bone labeled with Anti-MMP-13 Polyclonal Antibody, Unconjugated (ABIN670341) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
315,94 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of MMP13(arrow) using rabbit polyclonal MMP13 Antibody (ABIN390137). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the MMP13 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Rind (Kuh) Kaninchen Unkonjugiert IP, IHC, WB Western blot analysis of MMP-13 expression with Jurkat cell lysate. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
384,12 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: MMP13 Antibody [NBP2-17310] - Sample (30 ug of whole cell lysate) A: NT2D1 10% SDS PAGE gel, diluted at 1:1000. Immunocytochemistry/Immunofluorescence: MMP-13 Antibody [NBP2-17310] - NT2D1 cells were fixed in ice-cold MeOH for 5 min. Green: MMP13 protein stained by MMP13 antibody [N3C1], Internal diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
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Rind (Kuh) Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, SimWes, WB Immunocytochemistry/Immunofluorescence: MMP-13 Antibody [NBP1-45723] - MMP-13 antibody was tested at 1:50 in MDA-MB-231 cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Image objective 40x. Western Blot: MMP-13 Antibody [NBP1-45723] - Analysis of MMP-13 in human full-length recombinant protein using anti-MMP-13 antibody. Image from verified customer review. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
297,00 €
Details
Human Maus Unkonjugiert IF, IHC, IHC (p), WB Immunohistochemistry: MMP-13 Antibody (2D8) [NBP2-45887] - Analysis of Carcinoma of Human bladder tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Western Blot: MMP-13 Antibody (2D8) [NBP2-45887] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMP-13. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
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Human Kaninchen Unkonjugiert IF, IHC (p), WB 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
385,00 €
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MMP13 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Matrix Metallopeptidase 13 (Collagenase 3) Antikörper

  1. Human Polyclonal MMP13 Primary Antibody für EIA, IHC (p) - ABIN358686 : Roy-Beaudry, Martel-Pelletier, Pelletier, MBarek, Christgau, Shipkolye, Moldovan: Endothelin 1 promotes osteoarthritic cartilage degradation via matrix metalloprotease 1 and matrix metalloprotease 13 induction. in Arthritis and rheumatism 2003 (PubMed)
    Zeige alle 5 Referenzen für 358686

  2. Human Polyclonal MMP13 Primary Antibody für IF (p), IHC (p) - ABIN670341 : Luo, Zhang, Wang, Hu, Song, Su, Zhang: Alendronate retards the progression of lumbar intervertebral disc degeneration in ovariectomized rats. in Bone 2013 (PubMed)
    Zeige alle 4 Referenzen für 670341

  3. Cow (Bovine) Polyclonal MMP13 Primary Antibody für IP, IHC - ABIN223238 : Spinale, Escobar, Mukherjee, Zavadzkas, Saunders, Jeffords, Leone, Beck, Bouges, Stroud: Cardiac-restricted overexpression of membrane type-1 matrix metalloproteinase in mice: effects on myocardial remodeling with aging. in Circulation. Heart failure 2009 (PubMed)
    Zeige alle 2 Referenzen für 223238

  4. Human Monoclonal MMP13 Primary Antibody für IHC (p), IP - ABIN180404 : Pei, Yi: A high-level mammalian expression system based on the Madin-Darby canine kidney cell line. in Protein expression and purification 1998 (PubMed)
    Zeige alle 2 Referenzen für 180404

  5. Cow (Bovine) Polyclonal MMP13 Primary Antibody für WB - ABIN2786656 : Borghese, Chiche, Vernerey, Chenot, Mir, Bijaoui, Bonaiti-Pellié, Chapron: Genetic polymorphisms of matrix metalloproteinase 12 and 13 genes are implicated in endometriosis progression. in Human reproduction (Oxford, England) 2008 (PubMed)
    Zeige alle 2 Referenzen für 2786656

  6. Human Monoclonal MMP13 Primary Antibody für IF, IHC - ABIN4334944 : Huang, Ao, Li, Wu, Xu, Deng, Chen, Yin, Cheng: Autophagy Protects Advanced Glycation End Product-Induced Apoptosis and Expression of MMP-3 and MMP-13 in Rat Chondrocytes. in BioMed research international 2017 (PubMed)

  7. Cow (Bovine) Polyclonal MMP13 Primary Antibody für ICC, IF - ABIN4334942 : Ma, Liu, Wang, Chen, Liu, Li, Xiang, Wei, Duan, Han: Tamoxifen induces the development of hernia in mice by activating MMP-2 and MMP-13 expression. in Biochimica et biophysica acta 2015 (PubMed)

  8. Human Polyclonal MMP13 Primary Antibody für IHC (p), WB - ABIN390137 : Im, Pacione, Chubinskaya, Van Wijnen, Sun, Loeser: Inhibitory effects of insulin-like growth factor-1 and osteogenic protein-1 on fibronectin fragment- and interleukin-1beta-stimulated matrix metalloproteinase-13 expression in human chondrocytes. in The Journal of biological chemistry 2003 (PubMed)

Weitere Antikörper gegen Matrix Metallopeptidase 13 (Collagenase 3) Interaktionspartner

Zebrafish Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. MeHg impairs tail development at least partially by activation of the tissue remodeling proteases Mmp9 (zeige MMP9 Antikörper) and Mmp13.

  2. Zebra fish embryogenesis requires MMP-13 and dexamethasone and hydrocortisone modulate the expression of this gene, leading to increased activity and potentially contributing to subsequent dysmorphogenesis.

  3. JNK (zeige MAPK8 Antikörper)-Mmp13 signaling pathway plays an essential role in regulating the innate immune cell migration in response to severe injury in vivo

Xenopus laevis Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. XCL3 and XCL4 can be differentially induced by prolactin (zeige PRL Antikörper) and thyroid hormone (zeige PTH Antikörper)(3)

Mouse (Murine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. The progressive process of articular cartilage degeneration was significantly delayed in the knee joints of Ddr2 (zeige DDR2 Antikörper)-deficient mice in comparison to their control littermates. Articular cartilage damage in the knee joints of the mice was associated with increased expression profiles of both Ddr2 (zeige DDR2 Antikörper) and matrix metalloproteinase 13.

  2. Postnatal chondrocyte-specific deletion of Hdac3 (zeige HDAC3 Antikörper) with an inducible Col2a1 (zeige COL2A1 Antikörper)-Cre caused premature production of pErk1/2 and Mmp13 in the growth plate.

  3. Mmp13 is selectively regulated of by 1,25-Dihydroxyvitamin D3, PTH (zeige PTH Antikörper), and Osterix (zeige SP7 Antikörper) through distal enhancers.

  4. Our study contributes to the understanding of the role of HIF1alpha (zeige HIF1A Antikörper) in OA and highlights the HIF1alpha (zeige HIF1A Antikörper)-beta-catenin (zeige CTNNB1 Antikörper) interaction, thus providing new insights into the impact of hypoxia in articular cartilage.

  5. Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1 (zeige MMP1 Antikörper)/protease-activated receptor-1 (zeige F2R Antikörper) axis may play a role in neurogenesis following physiological and/or pathological stimuli.

  6. IL-1Ra (zeige IL1RN Antikörper) is associated with MMP-13 expression and has a novel function in such regulation without interference of the IL-1 (zeige IL1A Antikörper) signaling cascade.

  7. We reveal a novel role of AP-2epsilon in the regulation of gene expression in articular chondrocytes, as well as in osteoarthritis development, through modulation of Mmp13 expression and activity.

  8. B-16 melanoma cells with up-regulated MMP-13 expression promoted invasion of tumor cells through Matrigel compared with control cells transfected with empty vector. Knocked-down MMP-13 expression also decreased invading cell numbers.

  9. MMP-12 (zeige MMP12 Antikörper) and MMP-13 alter strain K infection in mice and play a role in inflammatory regulation by modulating cytokine levels.

  10. Data indicate that tamoxifen decreased collage type II COL2A1 (zeige COL2A1 Antikörper) by activating matrix metallopeptidases MMP-2 (zeige MMP2 Antikörper)/13 expression.

Human Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. High MMP13 expression is associated with intervertebral disc degeneration.

  2. data demonstrate that MMP-13 is critical for the development of osteolytic lesions in Multiple myeloma and that targeting the MMP-13 protein - rather than its catalytic activity - constitutes a potential approach to mitigating bone disease in affected patients.

  3. Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritic chondrocytes, which manifested in increased expression of ADAMTS5 (zeige ADAMTS5 Antikörper), MMP13, and decreased COL2A1 (zeige COL2A1 Antikörper) expression.

  4. Matrix metalloprotease (zeige ADAM8 Antikörper) (MMP) regulation was the top pathway involved in gingival aging. MMP3 (zeige MMP3 Antikörper), MMP9 (zeige MMP9 Antikörper), MMP12 (zeige MMP12 Antikörper), and MMP13 were upregulated in old gingival tissues, concomitantly with interleukin-1 beta (IL1B (zeige IL1B Antikörper)) expression.

  5. these findings support roles for both cFOS (indirect) and ATF3 (zeige ATF3 Antikörper) (direct) in effecting MMP13 transcription in human chondrocytes.

  6. Oxytocin prevents cartilage matrix destruction via regulating MMP1 (zeige MMP1 Antikörper) and MMP13.

  7. These studies have uncovered a new, ATP6V1H (zeige ATP6V1H Antikörper)-mediated pathway that regulates bone formation, and defines a new mechanism of disease that leads to bone loss. We propose that MMP9 (zeige MMP9 Antikörper)/MMP13 could be therapeutic targets for patients with this rare genetic disease.

  8. To conclude, Pseudomonas aeruginosa infection induced the expression of matrix metalloproteinases, and Pseudomonas aeruginosa type III secretion system appeared to be a key player in MMP-12 (zeige MMP12 Antikörper) and MMP-13 expression, which is further controlled by NF-kappaB (zeige NFKB1 Antikörper) signaling.

  9. In osteoarthritis (OA) chondrocytes, hydrostatic pressure (HP) restores the expression levels of some miRNAs, downregulates MMP-13, ADAMTS-5 (zeige ADAMTS5 Antikörper), and HDAC-4 (zeige HDAC4 Antikörper), and modulates the Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) pathway activation.

  10. These results suggested that HIF-2alpha (zeige EPAS1 Antikörper) may cause meniscal matrix degradation by transactivation of MMP-13

Horse (Equine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. The DNA microarray analysis for matrix metalloproteinase (zeige MMP20 PLURAL_@17598@) (MMP)-related mRNA expression in equine superficial digital flexor tendinitis indicated that mRNA level of MMP-13 was apparently up-regulated in the tendinitis as compared to normal tendon.

Cow (Bovine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. p38 (zeige MAPK14 Antikörper) phosphorylation and MMP13 expression are regulated by Rho/ROCK activation, and support the potential novel pathway that Rho/ROCK is in the upper part of the mechanical stress-induced matrix degeneration cascade in cartilage.

  2. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.

  3. MMP-13 treatment of fresh articular cartilage results in cleaved fibromodulin (zeige FMOD Antikörper) fragments

  4. increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 (zeige MMP1 Antikörper) and MMP-13 (follicular apex (zeige APEX1 Antikörper) vs. base) for the preovulatory collagenolysis required for follicle rupture

  5. involvement of p38 MAP kinase (zeige MAPK14 Antikörper) in the hyaluronan oligosaccharide induction of MMP-13

  6. MMP-13 and collagenase have roles in chondrocyte hypertrophy induced by type II collagen (zeige COL2A1 Antikörper)

  7. At high but naturally occurring concentrations the collagen peptide CB12 (zeige PABPC4 Antikörper)-II induced an increase in the expressions of MMP-13 and cleavage of type II collagen (zeige COL2A1 Antikörper) by collagenase in the mid zone and also in the superficial zone.

Rabbit Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. These results suggest that PEP-1-SIRT2 (zeige SIRT2 Antikörper) promotes matrix metalloproteinases-induced dedifferentiation via ERK (zeige MAPK1 Antikörper) signaling in articular chondrocytes.

  2. chitosan-pDNA nanoparticles encoding shRNA targeting MMP-3 (zeige MMP3 Antikörper) and -13 had great potential in silencing the dedifferentiation-related genes for regenerating prolonged and endurable cartilage.

  3. Leptin (zeige LEP Antikörper) can induce MMP-13 and have a synergistic induction effect on NO with TNF-alpha (zeige TNF Antikörper) in rabbit articular chondrocytes in vitro.

Pig (Porcine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Interaktionspartner

  1. TNF-alpha (zeige TNF Antikörper) induced MMP-13 expression by condylar cells might be involved in the degradation of the juvenile condyle.

Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Antigen-Profil

Protein Überblick

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Genbezeichner und Symbole assoziert mit MMP13

  • matrix metalloproteinase 13a (mmp13a) Antikörper
  • matrix metalloproteinase 13 (MGC68994) Antikörper
  • matrix metallopeptidase 13 (collagenase 3) (MMP13) Antikörper
  • matrix metallopeptidase 13 (collagenase 3) (mmp13) Antikörper
  • matrix metalloproteinase 13 (LOC100136348) Antikörper
  • matrix metalloproteinase 13 (mmp13) Antikörper
  • collagenase 3 (MMP-13) Antikörper
  • matrix metallopeptidase 13 (Mmp13) Antikörper
  • matrix metalloproteinase 13 precursor (MMP-13) Antikörper
  • cb1034 Antikörper
  • Clg Antikörper
  • CLG3 Antikörper
  • gene A Antikörper
  • MANDP1 Antikörper
  • MGC108008 Antikörper
  • MMP-13 Antikörper
  • Mmp1 Antikörper
  • MMP13 Antikörper
  • xcl3 Antikörper
  • xCol Antikörper

Bezeichner auf Proteinebene für MMP13

matrix metalloproteinase 13 , MMPLg , MMPLh , matrix metallopeptidase 13 (collagenase 3) , collagenase 3 , gene A , gene 11 , collagenase-3 , collagenase 3-like , Collagenase-3 , collagenase-1 , interstitial collagenase , matrix metalloproteinase-13 , MMP-13 , UMRCASE , matrix metalloproteinase 13 (collagenase 3)

GENE ID SPEZIES
387293 Danio rerio
379552 Xenopus laevis
451513 Pan troglodytes
493679 Felis catus
613098 Xenopus (Silurana) tropicalis
703980 Macaca mulatta
772008 Gallus gallus
100012553 Monodelphis domestica
100136348 Salmo salar
100396943 Callithrix jacchus
100462632 Pongo abelii
100526826 Ictalurus punctatus
100552256 Anolis carolinensis
100584961 Nomascus leucogenys
397823 Xenopus laevis
17386 Mus musculus
171052 Rattus norvegicus
4322 Homo sapiens
100009711 Equus caballus
281914 Bos taurus
100008685 Oryctolagus cuniculus
398056 Xenopus laevis
395683 Gallus gallus
403763 Canis lupus familiaris
443113 Ovis aries
397346 Sus scrofa
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