Matrix Metallopeptidase 11 (Stromelysin 3) Proteine (MMP11)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Zusätzlich bieten wir Ihnen MMP11 Antikörper (140) und MMP11 Kits (39) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MMP11 17385 Q02853
MMP11 25481 Q499S5
MMP11 4320 P24347
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Showing 10 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Ratte His tag,S tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
822,86 €
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.929,84 €
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HOST_Escherichia coli (E. coli) Human His-GST 10% SDS-PAGE stained with Coomassie Blue (CB) and peptide fingerprinting by MALDI-TOF mass spectrometry 50 μg Anmelden zum Anzeigen 2 bis 5 Tage
504,17 €
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HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
533,33 €
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HOST_Escherichia coli (E. coli) Maus His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
640,00 €
Details
Hefe Xenopus laevis His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.935,08 €
Details
HOST_Escherichia coli (E. coli) Human His-GST   50 μg Anmelden zum Anzeigen 7 bis 8 Tage
537,60 €
Details
HOST_Escherichia coli (E. coli) Ratte Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
1.008,33 €
Details

MMP11 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,

Rat (Rattus) ,
,
Human
,

Weitere Proteine zu Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) Interaktionspartnern

Mouse (Murine) Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) Interaktionspartner

  1. Results show that MMP-11 has a paracrine function during mammary gland development that might be harnessed to promote tumor progression, exposing a new link between development and malignancy.

  2. point-out the paradoxical role of MMP11 in favoring the onset and growth of lung metastases but limiting lung foci number, and inhibiting the cancer cell dissemination to other organs

  3. investigation of a potential role of MMP-11 in adipose tissue development

  4. The increased levels of ST-3 in the thymus may be due to the presence of macrophages responsible for clearance of apoptotic cells

  5. downregulated by deglycosylation of CD147 (zeige BSG Proteine) in hepatocarcinoma cells

  6. These data together provide compelling evidence into the function of MMP-11 and suggest that MMP-11 act as a tumor lymphatic metastasis-associated gene.

  7. These findings reveal that the tumor biological marker CD147 (zeige BSG Proteine) functionally mediates MMP-11, VEGF-A (zeige VEGFA Proteine) expression and tumor lymphatic metastasis.

  8. Mmp11 exhibits collagenolytic function against collagen VI under normal conditions.

  9. Our study describes the identification of MMP11 as a novel broadly expressed tumor associated antigen as target candidate for cancer immunotherapy.

Human Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) Interaktionspartner

  1. the data demonstrate that miR125a5p functions as a tumor suppressor gene and serves an important role in inhibiting osteosarcoma cell migration, invasion and EMT (zeige ITK Proteine) by targeting MMP11.

  2. MMP-11 overexpression is associated with aggressive tumor phenotype and unfavorable clinical outcome in urothelial carcinomas.

  3. Our study established that high serum levels of MMP-11 are associated with poor clinical outcome and may serve as a prognostic biomarker in colon cancer patients.

  4. Overexpression of MMP-11 was discovered in sera of cancer patients compared with normal control group as well as in multiple tumor tissue specimens, such as gastric cancer, breast cancer, and pancreatic cancer. At present, some evidence supports that MMP-11 may work as a significant tumor biomarker for early detection of cancer, tumor staging, prognostic analysis, monitoring recurrence [review]

  5. Matrix metalloproteinase 11 has a role in degenerating intervertebral disc disease

  6. combined effects of the MMP-11 gene polymorphisms and environmental carcinogens are related to an increased risk for the development of OSCC and may be a predictive factor for tumor lymph node metastasis in Taiwanese with OSCC

  7. results indicated that both CD147 (zeige BSG Proteine) and MMP-11 may be involved in the progression of colorectal cancer, and they are potential prognostic factors and might become new therapeutic targets for CRC (zeige CALR Proteine) patients

  8. High Expression of Matrix Metalloproteinase-11 is associated with Cholangiocarcinoma.

  9. study showed that plasma level of MMP-11 may be useful for assessment of the disease progression, especially lymph node metastasis, in patients with OSCC

  10. MMP-14 (zeige MMP14 Proteine) function might represent one critical regulatory mechanism to control the extent of pericellular MMP-11 bioavailability and protect cells from excessive/inappropriate MMP-11 function.

Xenopus laevis Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) Interaktionspartner

  1. Transgenic tadpoles were prepared with an elastase promoter driving either the ST3 gene or the constitutively active form of Notch (zeige NOTCH1 Proteine) (IC).

  2. analysis of substrate specificity for stromelysin-3: alpha1-PI is unlikely to be a physiological substrate

  3. ST3 regulates cell fate and tissue morphogenesis through direct or indirect extracellular matrix remodeling

  4. Laminin receptor precursor cleavage by ST3 plays a role in both physiological and pathological processes.

  5. thyroid hormone (zeige PTH Proteine) regulation of Xenopus laevis Stromelysin-3 is mediated by a DNA element in the first intron

  6. Mutational analysis of the cleavage of the cancer-associated laminin receptor by stromelysin-3 reveals the contribution of flanking sequences to site recognition and cleavage efficiency.

  7. ST3 expression, in the absence of T3 hormone, caused significant muscle cell death in the tail of premetamorphic transgenic tadpoles

MMP11 Protein Überblick

Protein Überblick

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.

Genbezeichner und Symbole assoziert mit MMP11

  • matrix metallopeptidase 11 (Mmp11)
  • matrix metallopeptidase 11 (stromelysin 3) (MMP11)
  • matrix metallopeptidase 11 (stromelysin 3) (Mmp11)
  • matrix metallopeptidase 11 (stromelysin 3) (mmp11)
  • matrix metalloproteinase 11 (LOC100101604)
  • SL-3 Protein
  • ST3 Protein
  • STMY3 Protein

Bezeichner auf Proteinebene für MMP11

MMP-11 , SL-3 , matrix metalloproteinase 11 , matrix metalloproteinase-11 , stromelysin 3 , stromelysin-3 , Matrix metalloproteinase 11 (stromelysin 3) , stromelysin III , ST3 , gene 14

GENE ID SPEZIES
17385 Mus musculus
25481 Rattus norvegicus
4320 Homo sapiens
486408 Canis lupus familiaris
100153503 Sus scrofa
100713229 Cavia porcellus
379501 Xenopus laevis
100101604 Oryctolagus cuniculus
539109 Bos taurus
Ausgewählte Anbieter für MMP11 Proteine (MMP11)
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