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transports lactic acid and other monocarboxylic acids. Zusätzlich bieten wir Ihnen Malignant T Cell Amplified Sequence 1 Proteine (13) und Malignant T Cell Amplified Sequence 1 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal MCTS1 Primary Antibody für EIA, WB - ABIN453186
Kasiappan, Shih, Chu, Chen, Liu, Huang, Choy, Shu, Din, Chu, Hsu: Loss of p53 and MCT-1 overexpression synergistically promote chromosome instability and tumorigenicity. in Molecular cancer research : MCR 2009
Zeige alle 3 Referenzen für ABIN453186
Chicken Polyclonal MCTS1 Primary Antibody für WB - ABIN2779047
Shi, Levenson, Gartenhaus: Identification and characterization of a novel enhancer for the human MCT-1 oncogene promoter. in Journal of cellular biochemistry 2003
Human Polyclonal MCTS1 Primary Antibody für WB - ABIN152954
Kumar, Kant, Singh et al.: Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage ... in Toxicology and applied pharmacology 2013
Human Polyclonal MCTS1 Primary Antibody für WB - ABIN4891880
Haas, Ngo, Li, Schleich, Qu, Vanyai, Cullen, Cardona-Alberich, Gladwyn-Ng, Pagnamenta, Taylor, Stewart, Kini, Duncan, Teleman, Keays, Heng: De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation. in Cell reports 2016
MCT1 inhibition impairs proliferation of glycolytic breast cancer cells co-expressing MCT1 and MCT4 (zeige SLC16A3 Antikörper) via disruption of pyruvate rather than lactate export.
This study demonstrated that MCT1 was up regulation in ipsilateral site of brain afeter cerebral ischemia.
The soleus, liver and heart were the main tissues that showed improved the MCT1 mRNA expression, indicating its important role in controlling MLSS concentration in mice.
Exercise-induced changes in tumour LDH-B (zeige LDHB Antikörper) and MCT1 expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice
Chronic lactate administration after exercise increases MCT1 protein expression, which can be involved in the regulation of the observed increase in muscle glycogen (zeige GYS1 Antikörper) storage after exercise training.
This study showed that mouse MCT1, MCT2 (zeige SLC16A7 Antikörper), and MCT4 (zeige SLC16A3 Antikörper) are expressed in the PNS. While DRG neurons express MCT1, myelinating Schwann cells.
These data for the first time demonstrate that MCT1 is critical for regeneration of both sensory and motor axons in mice following sciatic nerve crush
Study demonstrated that PTEN (zeige PTEN Antikörper) loss and MCT-1 induction synergistically promoted the neoplastic multinucleation via the Src (zeige SRC Antikörper)/p190B (zeige ARHGAP5 Antikörper) signaling activation.
in Parkinson's disease, the levels of MCT1, MCT2 (zeige SLC16A7 Antikörper) and GLUT1 (zeige SLC2A1 Antikörper) is not changed following dopaminergic neurodegeneration
results suggest that a reduction in mitochondria is a result, rather than the cause, of the metabolic deficiency observed in Basigin-null mice, and likely occurs because of reduced metabolic activity in the absence of MCT1 expression.
MCT1 (zeige CMA1 Antikörper) and MCT4 (zeige SLC16A4 Antikörper) expression levels were associated with worse prognosis and shorter overall survival.
MCT1 (zeige CMA1 Antikörper) may be acting as an uptake transporter and MCT4 (zeige SLC16A4 Antikörper) as an efflux system across the basolateral membrane for ferulic acid, and that this process is stimulated by butyric acid.
After indirect co-culture, OP was increased in the BxPc-3 and Panc-1 cells; correspondingly, succinate dehydrogenase (zeige SDHA Antikörper), FH and MCT (zeige MCAT Antikörper) expression were increased. After the MCT1 (zeige CMA1 Antikörper)-specific inhibitor removed 'tumor-stromal' metabolic coupling, the migration and invasion abilities of the pancreatic cancer cells were decreased.
Data suggest that inhibition of mnocarboxylate transporters MCT1 (zeige CMA1 Antikörper) and MCT4 (zeige SLC16A4 Antikörper) may have clinical relevance in pancreatic ductal adenocarcinoma (PDAC).
Results found that MCT (zeige MCAT Antikörper) contributes to endothelial cell growth and tube formation via up-regulation of angiopoietin-1 (zeige ANGPT1 Antikörper) expression suggesting that MCT (zeige MCAT Antikörper) plays an important role in pancreatic cancer angiogenesis and tumor growth via activating the angiopoietin-1 (zeige ANGPT1 Antikörper) pathway.
The targeting of MCT1 (zeige CMA1 Antikörper) and PFKFB3 (zeige PFKFB3 Antikörper) regulated cell proliferation.
MCT1 (zeige CMA1 Antikörper) expression associates with the SCC (zeige CYP11A1 Antikörper) type and metastatic behavior of AC, whereas MCT4 (zeige SLC16A4 Antikörper) expression concomitantly increases from in situ SCC (zeige CYP11A1 Antikörper) to invasive SCC (zeige CYP11A1 Antikörper) and is significantly associated with the AC type. Consistently, FOXM1 (zeige FOXM1 Antikörper) expression is statistically associated with MCT1 (zeige CMA1 Antikörper) positivity in SCC (zeige CYP11A1 Antikörper), whereas the expression of FOXO3a (zeige FOXO3 Antikörper), a FOXM1 (zeige FOXM1 Antikörper) functional antagonist, is linked to MCT1 (zeige CMA1 Antikörper) negativity
This study investigated MCT1 (zeige CMA1 Antikörper) protein abundance in various human intestinal tissues.
MCT1 (zeige CMA1 Antikörper) affects the plasma lactate decrease .
The aim of this study was to investigate the association between the MCT1 (zeige CMA1 Antikörper) A1470T polymorphism and fat-free (zeige VPS51 Antikörper) mass in young Italian elite soccer players. The MCT1 (zeige CMA1 Antikörper) T allele is associated with the percentage of fat-free (zeige VPS51 Antikörper) mass in young elite male soccer players.
Data indicate that monocarboxylate transporters (MCTs1-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.
This study confirmed age-dependent changes of MCT1 expression in the rumen epithelium of newborn calves and showed that its expression might be affected by liquid feed type.
These findings show that MCT 1 increases with the development of rumen function and also in adult animals MCT 1 may change with the feeding.
The expression and distribution of monocarboxylate transporter 1 along the gastrointestinal tract of calves suggest it may play a role in transport of short chain fatty acids and their metabolites.
The results show that monocarboxylate transporter 1 (MCT1) is a major route for short chain fatty acids (SCFA) efflux across the basolateral membrane of bovine large intestine and that it could play a role in the regulation of intracellular pH.
Data suggest that expression of MCT1 in intestinal mucosa can be altered by diet; here, expression of MCT1 is down-regulated in colonic mucosa by high-protein diet and appears to be linked to fermentation of dietary proteins by intestinal microbes.
MCT1-mRNA showed a higher expression in the ileum; feeding inulin-coated butyrate resulted in an increased ileal surface; delivery of butyrate to the colon requires a more resistant inulin-coating.
The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.
malignant T cell amplified sequence 1
, malignant T cell-amplified sequence 1
, malignant T-cell-amplified sequence 1
, multiple copies T-cell malignancies
, multiple copies T-cell malignancies 1
, Malignant T cell amplified sequence 1-A
, malignant T cell-amplified sequence 1-A
, malignant T-cell-amplified sequence 1-A
, MCT 1
, monocarboxylate transporter 1
, solute carrier family 16 (monocarboxylic acid transporters), member 1
, solute carrier family 16 member 1
, solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
, solute carrier 16 (monocarboxylic acid transporter), member 1
, monocarboxylate transporter 1a