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The membrane-associated protein encoded by Mod2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen Malic Enzyme Complex, Mitochondrial Proteine (2) und viele weitere Produktgruppen zu diesem Protein an.
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Compared with the sensitive group, both mdr1 (zeige TBC1D9 Antikörper) mRNA and P-gp (zeige ABCB4 Antikörper) expressions increased in the resistant group
an SNP in ABCB1 (zeige ABCB1 Antikörper) (rs2032582: 2677G > T/A) was significantly associated with atorvastatin-induced liver injury (AILI) indicating that the G allele might be a risk factor for AILI in Japanese population
impact of CYP4F2 (zeige CYP4F2 Antikörper), ABCB1 (zeige ABCB1 Antikörper), and GGCX (zeige GGCX Antikörper) polymorphisms on bleeding episodes associated with acenocoumarol in Russian patients with atrial fibrillation
Collectively, the data establish a hitherto unknown liaison among MDR1 (zeige TBC1D9 Antikörper), BMI1 (zeige BMI1 Antikörper) and TIP60 (zeige KAT5 Antikörper) and provide mechanistic insights into cisplatin-induced MDR1 (zeige TBC1D9 Antikörper) expression resulting in acquired cross-resistance against paclitaxel, doxorubicin and likely other anticancer drugs.
High ABCB1 (zeige ABCB1 Antikörper) expression is associated with hepatocellular carcinoma.
Our data suggest that the C1236T and G2677A/T SNPs in the MDR1 (zeige TBC1D9 Antikörper) gene are associated with Crohn's disease and the C1236T risk allele with a more severe course of disease in Algerian pediatric patients.
ATPase (zeige DNAH8 Antikörper) measurements imply that DCV and Ho are similarly handled by ABCB1 (zeige ABCB1 Antikörper), whereas ABCG2 (zeige ABCG2 Antikörper) seems to transport DVC more effectively. In addition, we have developed an image-based high content microscopy screening method for simultaneous in situ measurement of the cellular activity and expression of the ABCG2 (zeige ABCG2 Antikörper) multidrug transporter
These results show that multidrug resistant leukemia cell microparticle regulation of ABCC1 (zeige ABCC1 Antikörper) in recipient cells is governed by the transfer of both miR (zeige MLXIP Antikörper)-326 and ABCB1 (zeige ABCB1 Antikörper) from donor cells
he modulatory effect of acacetin-doxorubicin combination on doxorubicin influx and efflux was mediated through downregulation of MDR1 (zeige TBC1D9 Antikörper) treansporter in non-small-cell lung carcinoma (NSCLC) cells.
An additional action of osimertinib that directly inhibits the function of ABCB1 (zeige ABCB1 Antikörper).
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
malic enzyme complex, mitochondrial
, malic enzyme, mitochondrial regulatory
, malic enzyme, mitochondrial structural
, P-glycoprotein 1
, colchicin sensitivity
, doxorubicin resistance
, multidrug resistance protein 1