Maelstrom Spermatogenic Transposon Silencer (MAEL) ELISA Kits

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Zusätzlich bieten wir Ihnen MAEL Proteine (6) und MAEL Antikörper (5) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
MAEL 98558 Q8BVN9
MAEL 84944 Q96JY0
Anti-Ratte MAEL MAEL 364039  
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Top MAEL ELISA Kits auf antikoerper-online.de

Showing 4 out of 4 products:

Katalog Nr. Reaktivität Sensitivität Bereich Menge Anbieter Lieferzeit Preis Details
Human
96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
788,70 €
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Maus
96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
788,70 €
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Rind (Kuh)
96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
945,85 €
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Schwein
96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
945,85 €
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Weitere ELISA Kits für MAEL Interaktionspartner

Mouse (Murine) Maelstrom Spermatogenic Transposon Silencer (MAEL) Interaktionspartner

  1. MAEL HMG (zeige SSRP1 ELISA Kits)-box domain may contribute to MAEL function in selective processing of retrotransposon RNA into piRNAs.

  2. an important role for Mael in early oogenesis and during germ-cell differentiation from embryonic stem cells

  3. This study demonstrates that MAEL, a nuage component, is indispensable for the silencing of transposable elements (TEs (zeige TES ELISA Kits)) and identifies the initiation of meiosis as an important step in (TE) control in the male germline.

Human Maelstrom Spermatogenic Transposon Silencer (MAEL) Interaktionspartner

  1. Data suggest that overexpression of MAEL, caused by gene amplification and/or decreased miR-186, has a critical oncogenic role in UCB pathogenesis by downregulation of MTSS1.

  2. Study demonstrated that MAEL interacts with Snail (zeige SNAI1 ELISA Kits) and inhibit E-cadherin (zeige CDH1 ELISA Kits) promoter activity. MAEL is an oncogene (zeige RAB1A ELISA Kits) that plays an important role in the development and progression of colon cancer.

  3. Immunofluorescence analysis showed that MAEL co-localizes with the stress granule marker PABPC1 (zeige PABPC1 ELISA Kits) in stress granules during oxidative stress. MAEL may be involved in miRNA-mediated gene silencing in SGs (zeige FBN1 ELISA Kits).

  4. Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition by way of Akt (zeige AKT1 ELISA Kits)/GSK-3beta (zeige GSK3b ELISA Kits)/Snail (zeige SNAI1 ELISA Kits) signaling.

  5. These results suggest that MAEL is a novel cancer/testis-associated gene and is regulated by DNA methylation (zeige HELLS ELISA Kits).

MAEL Antigen-Profil

Beschreibung des Gens

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage (By similarity).

Genbezeichner und Symbole assoziert mit MAEL

  • maelstrom homolog (Drosophila) (Mael) Antikörper
  • maelstrom homolog (Drosophila) (MAEL) Antikörper
  • maelstrom spermatogenic transposon silencer (MAEL) Antikörper
  • maelstrom spermatogenic transposon silencer (Mael) Antikörper
  • protein maelstrom homolog (LOC100737640) Antikörper
  • 4933405K18Rik Antikörper
  • AU019877 Antikörper
  • CT128 Antikörper
  • RGD1309333 Antikörper
  • RP11-102C16.1 Antikörper
  • SPATA35 Antikörper

Bezeichner auf Proteinebene für MAEL

protein maelstrom homolog , cancer/testis antigen 128 , maelstrom homolog , spermatogenesis associated 35

GENE ID SPEZIES
98558 Mus musculus
541073 Bos taurus
100048945 Sus scrofa
84944 Homo sapiens
364039 Rattus norvegicus
100737640 Sus scrofa
Ausgewählte Anbieter für MAEL (MAEL) ELISA Kits
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