anti-M-Phase phosphoprotein 8 (MPHOSPH8) Antikörper

Involved in transcriptional regulation. Zusätzlich bieten wir Ihnen M-Phase phosphoprotein 8 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MPHOSPH8 54737 Q99549
MPHOSPH8 75339 Q3TYA6
MPHOSPH8 290270 G3V8T1
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Top anti-M-Phase phosphoprotein 8 Antikörper auf antikoerper-online.de

Showing 10 out of 18 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert WB MPP8 antibody (mAb) tested by Western blot. Nuclear extract of HEK293 cells (20 µg per lane) probed with MPP8 antibody (mAb) (2 µg/ml dilution). 100 μg Anmelden zum Anzeigen 1 bis 3 Tage
497,22 €
Details
Human Kaninchen Unkonjugiert IP, WB Western Blot: mpp8 Antibody [NBP1-71808] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-MPP8 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. MPP8 was also immunoprecipitated by rabbit anti-MPP8 antibody NBP1-71807, which recognizes a downstream epitope. 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Kaninchen Unkonjugiert IP, WB Western Blot: mpp8 Antibody [NBP1-71809] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-MPP8 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. MPP8 was also immunoprecipitated by rabbit anti-MPP8 antibody NBP1-71808, which recognizes an upstream epitope. 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: mpp8 Antibody [NBP1-92136] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunocytochemistry/Immunofluorescence: mpp8 Antibody [NBP1-92136] - Staining of human cell line U-251 MG shows positivity in nucleus but not nucleoli & cytoplasm. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Maus Unkonjugiert IF, WB Western Blot analysis of MPHOSPH8 expression in transfected 293T cell line by MPHOSPH8 MaxPab polyclonal antibody.Lane 1: MPHOSPH8 transfected lysate(28.40 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to MPHOSPH8 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   50 μL Anmelden zum Anzeigen 11 bis 15 Tage
298,57 €
Details
Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 15 bis 21 Tage
800,82 €
Details
Human Maus Unkonjugiert WB   10 μg Anmelden zum Anzeigen 1 bis 3 Tage
136,11 €
Details
Human Kaninchen Unkonjugiert WB   200 μL Anmelden zum Anzeigen 7 bis 12 Tage
530,36 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   50 μL Anmelden zum Anzeigen 6 bis 8 Tage
495,58 €
Details

MPHOSPH8 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human
,
,
Mouse (Murine)


Rat (Rattus)


Weitere Antikörper gegen M-Phase phosphoprotein 8 Interaktionspartner

Human M-Phase phosphoprotein 8 (MPHOSPH8) Interaktionspartner

  1. The haploid screen identified HUSH, an epigenetic heterochromatin repressor complex composed of three subunits, TASOR, MPP8 and Periphilin (zeige PPHLN1 Antikörper). (Review)

  2. findings demonstrate MPP8 and SIRT1 (zeige SIRT1 Antikörper) reciprocally regulate each other's function at multiple molecular layers through physical interaction; disruption of MPP8-SIRT1 (zeige SIRT1 Antikörper) interaction de-represses E cadherin (zeige CDH1 Antikörper) expression and reduces cell motility and invasiveness suggesting this interplay plays critical role in MPP8- and SIRT1 (zeige SIRT1 Antikörper)-mediated epithelial-mesenchymal transition

  3. this study identified the HUSH (human silencing hub) complex, comprising three poorly characterized proteins, TASOR, MPP8, and periphilin (zeige PPHLN1 Antikörper); this complex is absent from Drosophila but is conserved from fish to humans.

  4. Knockdown analysis of MPP8 in HeLa cells resulted in derepression of a set of genes that are normally expressed in spermatogonia, spermatids and mature sperm, thereby indicating a role for this molecule in silencing testis-related genes in somatic cells.

  5. interaction of HN with MPP8 may play a role in oncogenesis because MPP8 increases tumor cell motility and invasion

  6. these results indicate that the chromatin association of MPP8 is regulated by Cdk (zeige CDK4 Antikörper)-dependent phosphorylation.

  7. These findings reveal the molecular mechanism of selective binding of human MPP8 chromodomain to methylated histone H3K9.

  8. We determined the crystal structure of MPP8 chromodomain in complex with H3K9me3 peptide. MPP8 interacts with at least six histone H3 (zeige HIST3H3 Antikörper) residues from glutamine (zeige GFPT1 Antikörper) 5 to serine 10.

  9. MPP8 mediates E-cadherin (zeige CDH1 Antikörper) gene silencing and promotes breast tumour cell motility and invasion.

M-Phase phosphoprotein 8 (MPHOSPH8) Antigen-Profil

Protein Überblick

Involved in transcriptional regulation. Specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes DNA methylation by recruiting DNMT3A to target CpG sites\; these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression (By similarity).

Genbezeichner und Symbole assoziert mit MPHOSPH8

  • M-phase phosphoprotein 8 (MPHOSPH8) Antikörper
  • M-phase phosphoprotein 8 (Mphosph8) Antikörper
  • 1500035L22Rik Antikörper
  • 4930548G07Rik Antikörper
  • Ab2-008 Antikörper
  • AU040635 Antikörper
  • HSMPP8 Antikörper
  • mpp8 Antikörper
  • RGD1305133 Antikörper
  • TWA3 Antikörper

Bezeichner auf Proteinebene für MPHOSPH8

M-phase phosphoprotein, mpp , M-phase phosphoprotein, mpp8 , two hybrid-associated protein 3 with RanBPM

GENE ID SPEZIES
54737 Homo sapiens
75339 Mus musculus
290270 Rattus norvegicus
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