Ly6/neurotoxin 1 Proteine (LYNX1)

LYNX1 encodes a member of the Ly-6/neurotoxin gene family, a group of lymphocyte antigens that attach to the cell surface by a glycosylphosphatidylinositol anchor and have a unique structure showing conserved 8-10 cysteine residues with a characteristic spacing pattern. Zusätzlich bieten wir Ihnen Ly6/neurotoxin 1 Antikörper (3) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
LYNX1 66004 Q9BZG9
LYNX1 23936 Q9WVC2
Ratte LYNX1 LYNX1 300018  
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
1.992,22 €
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Hefe Primaten His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
1.992,22 €
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Hefe Pan troglodytes His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
1.992,22 €
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LYNX1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Ly6/neurotoxin 1 (LYNX1) Interaktionspartnern

Human Ly6/neurotoxin 1 (LYNX1) Interaktionspartner

  1. These findings provide new insights into the acetylcholine receptor (zeige CHRNA1 Proteine)-mediated regulatory mechanism of SLURP-2 expression in keratinocytes.

  2. These studies suggest that lynx1 is a potential target both for development of drugs that may limit lung cancer growth as well as for drugs that may be effective for asthma or COPD (zeige ARCN1 Proteine) treatment.

  3. This epigenome-wide DNA methylation (zeige HELLS Proteine) analysis in postmortem hippocampus and prefrontal cortex specimens confirmed LYNX1 DNA methylation (zeige HELLS Proteine) profiles in major depression.

  4. SLURP-2 downregulated TNFalpha (zeige TNF Proteine) and IFNgamma R in T-cells and reduced IL-6 (zeige IL6 Proteine) production by macrophage

  5. Micromolar affinities and fast washout rates measured for ws-LYNX1 and its mutants are in contrast to nanomolar affinities and irreversibility of binding for alpha-bungarotoxin and similar snake alpha-neurotoxins also targeting alpha7 nAChR (zeige CHRNA7 Proteine).

  6. Computer modeling, based on ws-LYNX1 NMR structure and AChBP x-ray structure, revealed a possible mode of ws-LYNX1 binding.

  7. These results indicated that SLURP-2 competes with acetylcholine predominantly at the alpha3 nAChR (zeige CHRNA4 Proteine), and that receptor ligation with SLURP-2 delays keratinocyte differentiation and prevents apoptosis.

  8. LY-6K (zeige Ly6k Proteine),a novel member protein of the Ly-6/uPAR (zeige PLAUR Proteine) superfamily, is a significant new molecular marker for diagnosis and gene therapy in patients with breast cancer.

  9. anti-tumorigenic activities of SLURP-1 (zeige SLURP1 Proteine) and -2 were demonstrated both in vitro and in vivo.

  10. decreased Lynx1 is associated with squamous cell lung carcinoma

Mouse (Murine) Ly6/neurotoxin 1 (LYNX1) Interaktionspartner

  1. The results of this study suggested greater spine loss as a better correlate of elevated functional plasticity in adult Lynx1-KO mice.

  2. tPA (zeige PLAT Proteine) activity in V1 can be unmasked following 4 d of monocular deprivation when mice older than 2 months are raised in standard cages by the genetic removal of Lynx1, a negative regulator of adult plasticity.

  3. lynx1 KO animals over 1 year of age have clear ultrastructural differences in the striatum.

  4. Lynx1 has a role in shifting alpha4beta2 nicotinic receptor subunit stoichiometry by affecting assembly in the endoplasmic reticulum

  5. study identified an increase in expression of Lynx1 protein that prevented plasticity in the primary visual cortex late in life; Lynx1 expression maintains stability of mature cortical networks in the presence of cholinergic innervation

  6. Results show that lynx1 colocalizes with nAChRs on CNS neurons and physically associates with nAChRs and enhances receptor desensitization, resulting in a novel type of functional modulation

Rhesus Monkey Ly6/neurotoxin 1 (LYNX1) Interaktionspartner

  1. Lynx1 appears to act as a negative modulator of alpha7 nAChR (zeige CHRNA7 Proteine)-induced events by inhibiting Src (zeige SRC Proteine) activation.

Ly6/neurotoxin 1 (LYNX1) Protein Überblick

Protein Überblick

This gene encodes a member of the Ly-6/neurotoxin gene family, a group of lymphocyte antigens that attach to the cell surface by a glycosylphosphatidylinositol anchor and have a unique structure showing conserved 8-10 cysteine residues with a characteristic spacing pattern. Functional analysis indicates that this protein is not a ligand or neurotransmitter but has the capacity to enhance nicotinic acetylcholine receptor function in the presence of acetylcholine. This gene may also play a role in the pathogenesis of psoriasis vulgaris. Alternatively spliced variants encoding different isoforms have been identified.

Genbezeichner und Symbole assoziert mit Ly6/neurotoxin 1 Proteine (LYNX1)

  • Ly6/neurotoxin 1 (LYNX1)
  • Ly6/neurotoxin 1 (Lynx1)
  • RIKEN cDNA 2300005B03 gene (2300005B03Rik)
  • AI838844 Protein
  • SLURP-2 Protein
  • Slurp2 Protein

Bezeichner auf Proteinebene für Ly6/neurotoxin 1 Proteine (LYNX1)

Ly-6 neurotoxin-like protein 1 , SLURP-2 , ly-6/neurotoxin-like protein 1 , secreted Ly-6/uPAR domain-containing protein 2 , secreted Ly-6/uPAR-related protein 2 , secreted Ly6/uPAR related protein 2 , GC26 , secreted Ly6/uPAR related protein-2

GENE ID SPEZIES
66004 Homo sapiens
23936 Mus musculus
300018 Rattus norvegicus
516158 Bos taurus
574359 Macaca mulatta
464434 Pan troglodytes
69462 Mus musculus
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