anti-Kruppel-Like Factor 8 (KLF8) Antikörper

KLF8 encodes a protein which is a member of the Sp/KLF family of transcription factors. Zusätzlich bieten wir Ihnen KLF8 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KLF8 11279 O95600
KLF8 245671 Q8BLM0
KLF8 302582  
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Top anti-KLF8 Antikörper auf antikoerper-online.de

Showing 10 out of 54 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Human kidney WB Suggested Anti-KLF8 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:2500 Positive Control: Human Kidney 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Hund Kaninchen Unkonjugiert WB <b>WB Suggested Anti-KLF8 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate Host: Rabbit <br /> Target Name: KLF8 <br /> Sample Tissue: HepG2 Whole Cell lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Meerschweinchen Kaninchen Unkonjugiert WB <b>WB Suggested Anti-KLF8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Placenta 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN184763 staining (2µg/ml) of Human Kidney lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Human Ziege Unkonjugiert ELISA, WB ABIN249552 staining (2µg/ml) of Human Kidney lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Meerschweinchen Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Hund Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB Anti-KLF8 antibody, Western blotting Lane 1: SMMC Cell Lysate Lane 2: 293T Cell Lysate 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$375.38
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details

KLF8 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , ,
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Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-KLF8 Antikörper

  1. Cow (Bovine) Polyclonal KLF8 Primary Antibody für IHC, WB - ABIN2777342 : Lossi, Laugier-Anfossi, Depetris, Gecz, Gedeon, Kooy, Schwartz, Mattei, Croquette, Villard: Abnormal expression of the KLF8 (ZNF741) gene in a female patient with an X;autosome translocation t(X;21)(p11.2;q22.3) and non-syndromic mental retardation. in Journal of medical genetics 2002 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal KLF8 Primary Antibody für ELISA, WB - ABIN249552 : Ding, Grammer, Nelson, Guan, Stewart, Gladson: p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal KLF8 Primary Antibody für IF, WB - ABIN524708 : Schnell, Romagna, Jaehnert, Albrecht, Eigenbrod, Juerchott, Kretzschmar, Tonn, Schichor: Krüppel-like factor 8 (KLF8) is expressed in gliomas of different WHO grades and is essential for tumor cell proliferation. in PLoS ONE 2012 (PubMed)

Weitere Antikörper gegen KLF8 Interaktionspartner

Zebrafish Kruppel-Like Factor 8 (KLF8) Interaktionspartner

  1. Results demonstrate a novel role of Klf8, achieved via modulation of p53 (zeige TP53 Antikörper) and met expression, in the maintenance neuronal progenitors and development of Purkinje cells and the proliferation of granule cells in the cerebella of zebrafish embryos

Human Kruppel-Like Factor 8 (KLF8) Interaktionspartner

  1. expression of miR (zeige MLXIP Antikörper)-1236-3p was lower in lung adenocarcinoma tissues than that in adjacent normal tissue; in A549 cell line, miR (zeige MLXIP Antikörper)-1236-3p decreased ability of cell invasion and migration; furthermore, KLF8 is targeted by miR (zeige MLXIP Antikörper)-1236-3p, and expression of miR (zeige MLXIP Antikörper)-1236-3p is negatively correlated with KLF8; additionally, miR (zeige MLXIP Antikörper)-1236-3p suppressed the expression of KLF8 and EMT (zeige ITK Antikörper) (epithelial mesenchymal transition)-related genes

  2. Overexpression of KLF8 may contribute to the progression of pancreatic cancer, and downregulation of KLF8 expression by lentivirus-delivered shRNA is a novel therapeutic approach for PC.

  3. KLF8 plays a crucial role in proliferation and migration of bladder cancer cells

  4. KLF8-induced FHL2 (zeige FHL2 Antikörper) activation is a novel and critical signaling mechanism underlying human colorectal cancer invasion and metastasis.

  5. KLF8 and miR141/EGFR (zeige EGFR Antikörper) have roles in signaling pathway potentially crucial for breast cancer malignancy

  6. KLF8 suppression induced cell differentiation and inhibited tumorigenesis in colorectal cancer

  7. MiR (zeige MLXIP Antikörper)-135a inhibits migration and invasion and regulates epithelial-mesenchymal transition-related marker genes by targeting KLF8 in lung cancer cells.

  8. KLF8 is a novel epithelial to mesenchymal transition regulating transcription factor that involved in the progression of gastric cancer.

  9. In this review, we focus on the functions, roles, and regulatory networks of these five KLFs in HCC (zeige FAM126A Antikörper), summarize key pathways, and propose areas for further investigation

  10. A novel KLF8 to EPSTI1 to VCP (zeige vcp Antikörper) to NF-kappaB (zeige NFKB1 Antikörper) signaling mechanism potentially critical for breast cancer invasion and metastasis.

Mouse (Murine) Kruppel-Like Factor 8 (KLF8) Interaktionspartner

  1. Klf8 is highly expressed in various regions of the mouse brain and in particular in the neurons, where it was localized in the cell nuclei.

  2. KLF3 and KLF8 have overlapping roles in vivo and participate in the silencing of embryonic globin expression during development.

  3. KLF8 is a key component of the transcription factor network that controls terminal differentiation during adipogenesis.

  4. PARP-1 (zeige PARP1 Antikörper) as a novel KLF8-binding and -regulating protein and provided new insights into the mechanisms underlying the regulation of KLF8 nuclear localization, stability, and functions.

  5. These results identified the KLF8 activation domain located between residues 101-260 where the well-conserved Q118 and Q248 are essential for recruiting p300 (zeige NOTCH1 Antikörper) and PCAF (zeige KAT2B Antikörper) to activate target gene transcription.

  6. sumoylation of KLF8 negatively regulates its transcriptional activity and cellular functions

  7. Klf8 is repressed by Klf3 (zeige KLF3 Antikörper) and activated by Klf1 (zeige KLF1 Antikörper) in vivo.

  8. KLF8 has two N terminal regulatory regions, one surrounding S165 and K171 and the other being two tandem ZFs, which are critical for the regulation of KLF8 nuclear localization and its cellular functions

Pig (Porcine) Kruppel-Like Factor 8 (KLF8) Interaktionspartner

  1. results demonstrate that KLF8 can participate in regulating expression of alternate forms of HuR (zeige ELAVL1 Antikörper) mRNA along with NF-kappaB (zeige NFKB1 Antikörper) and other factors, depending on cellular contexts

KLF8 Antigen-Profil

Protein Überblick

This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit KLF8

  • Kruppel like factor 8 (KLF8) Antikörper
  • Kruppel-like factor 8 (klf8) Antikörper
  • Kruppel-like factor 8 (Klf8) Antikörper
  • Kruppel-like factor 8 (KLF8) Antikörper
  • A830097P10Rik Antikörper
  • BKLF3 Antikörper
  • klf8 Antikörper
  • Klf8-ps1 Antikörper
  • RGD1565831 Antikörper
  • ZNF74 Antikörper
  • ZNF741 Antikörper

Bezeichner auf Proteinebene für KLF8

Krueppel-like factor 8 , kruppel-like factor 8 , Kruppel-like factor 8 , basic krueppel-like factor 3 , basic kruppel-like factor 3 , zinc finger protein 741 , Kruppel-like factor 8, pseudogene 1

GENE ID SPEZIES
100051239 Equus caballus
562805 Danio rerio
100351857 Oryctolagus cuniculus
11279 Homo sapiens
245671 Mus musculus
302582 Rattus norvegicus
100154631 Sus scrofa
430697 Gallus gallus
525558 Bos taurus
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