Kinesin Family Member 1A (KIF1A) ELISA Kits

The protein encoded by KIF1A is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Zusätzlich bieten wir Ihnen KIF1A Antikörper (12) und KIF1A Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus KIF1A KIF1A 16560  
KIF1A 547 Q12756
Anti-Ratte KIF1A KIF1A 363288  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.051 ng/mL 0.156-10 ng/mL 96 Tests Anmelden zum Anzeigen 15 bis 17 Tage
$908.41
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Weitere ELISA Kits für KIF1A Interaktionspartner

Mouse (Murine) Kinesin Family Member 1A (KIF1A) Interaktionspartner

  1. these findings support a primary role for KIF1A in the anterograde transport of BACE1 (zeige BACE ELISA Kits).

  2. propose that KIF1A is essential for the survival and function of sensory neurons.

  3. The Doublecortin (zeige DCX ELISA Kits) specifically enhances binding of the ADP-bound Kif1a motor domain to microtubules. Dcx (zeige DCX ELISA Kits) is essential for the function of Kif1a, a kinesin-3 motor protein (zeige MYO7A ELISA Kits) that traffics synaptic vesicles.

  4. This study demonstrated that KIF1A is indispensable for BDNF (zeige BDNF ELISA Kits)-mediated hippocampal synaptogenesis and learning enhancement induced by enrichment.

  5. The KIF1A-microtubule binding free energy is dominated by van (zeige SLC11A2 ELISA Kits) der (zeige GDF3 ELISA Kits) Waals interactions and electrostatic interactions.

  6. crystal structures of monomeric KIF1A with three transition-state analogs; structures show that KIF1A uses two microtubule-binding loops in an alternating manner to change its interaction with microtubules during the ATP hydrolysis cycle

  7. propose a model mechanism for microtubule activation of Mg-ADP release from KIF1A

Human Kinesin Family Member 1A (KIF1A) Interaktionspartner

  1. De novo missense variant affecting the motor domain of KIF1A was identified as a cause of PEHO syndrome.

  2. Mutations outside the motor domain of the gene can cause (recessive) SPG30 and extends the genotype-phenotype association for KIF1A-related diseases.

  3. This study further delineates clinical features of de novo KIF1A mutations

  4. KIF1A variants in dominant and sporadic forms of hereditary spastic paraparesis.

  5. KIF1A should be considered a candidate gene for hereditary paraplegias regardless of inheritance pattern.

  6. Findings provide evidence that de novo missense mutations in the motor domain of KIF1A cause a more severe phenotype that overlaps with that associated with recessive mutations in the same gene.

  7. Data demonstrated that KIF1A promoter methylation can distinguish breast cancer cases from controls in plasma and was inversely associated with DNA repair capacity.

  8. This study establishes an essential role of the CC1 (zeige CCL14 ELISA Kits)-FHA (zeige CRY2 ELISA Kits) dimer for KIF1A/unc-104-mediated neuronal transport.

  9. Cytoplasmic dynein is active during minus- and plus-end directed motion, whereas kinesin is only active in the plus direction.

  10. The CC1 (zeige CCL14 ELISA Kits)-FHA (zeige CRY2 ELISA Kits) tandem likely functions as a hub for controlling the dimerization and activation of KIF1A.

KIF1A Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Genbezeichner und Symbole assoziert mit KIF1A

  • kinesin family member 1A (KIF1A) Antikörper
  • kinesin family member 1A (kif1a) Antikörper
  • kinesin family member 1A (Kif1a) Antikörper
  • ATSV Antikörper
  • C2orf20 Antikörper
  • C630002N23Rik Antikörper
  • Gm1626 Antikörper
  • HSN2C Antikörper
  • Kns1 Antikörper
  • MRD9 Antikörper
  • SPG30 Antikörper
  • UNC104 Antikörper

Bezeichner auf Proteinebene für KIF1A

kinesin family member 1A , N-3 kinesin , axonal transporter of synaptic vesicles , kinesin heavy chain member 1A , kinesin-like protein KIF1A , kinesin, heavy chain, member 1A, homolog of mouse , microtubule-based motor KIF1A , tmp_locus_27 , unc-104- and KIF1A-related protein , neuron-specific kinesin motor KIF1A

GENE ID SPEZIES
716855 Macaca mulatta
761007 Strongylocentrotus purpuratus
100013596 Monodelphis domestica
100057836 Equus caballus
100080479 Ornithorhynchus anatinus
100127546 Xenopus (Silurana) tropicalis
100565891 Anolis carolinensis
100582798 Nomascus leucogenys
16560 Mus musculus
100330443 Danio rerio
424849 Gallus gallus
547 Homo sapiens
486202 Canis lupus familiaris
527883 Bos taurus
363288 Rattus norvegicus
100517246 Sus scrofa
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