anti-Intestinal Cell (MAK-Like) Kinase (ICK) Antikörper

Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. Zusätzlich bieten wir Ihnen ICK Proteine (11) und ICK Kits (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ICK 22858 Q9UPZ9
ICK 56542 Q9JKV2
ICK 84411 Q62726
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Showing 10 out of 77 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ICK Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using ICK Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from NIH-3T3 cells treated with starved 24h, using ICK (Phospho-Tyr159) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: ICK Antibody [NBP1-81459] - Staining of human cell line U-251MG shows positivity in vesicles. Immunohistochemistry-Paraffin: ICK Antibody [NBP1-81459] - Staining of human colon shows strong cytoplasmic positivity with a granular pattern in glandular cells. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, treated with PBS 10uM 60', using ICK (Ab-159) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
600,64 €
Details
Human Maus Unkonjugiert ELISA, WB ICK polyclonal antibody (A01), Lot # 051103JC01 Western Blot analysis of ICK expression in Y-79 . ICK polyclonal antibody (A01), Lot # CAO0060412QCS1. Western Blot analysis of ICK expression in NIH/3T3. 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
241,60 €
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
801,43 €
Details
Human Kaninchen Unkonjugiert IF, IHC (p), ELISA 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
565,71 €
Details

ICK Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-ICK Antikörper

  1. Human Polyclonal ICK Primary Antibody für ICC, IF - ABIN4320963 : Häggarth, Hägglöf, Jaraj, Wester, Pontén, Ostman, Egevad: Diagnostic biomarkers of prostate cancer. in Scandinavian journal of urology and nephrology 2011 (PubMed)

  2. Human Polyclonal ICK Primary Antibody für ELISA, WB - ABIN564945 : Vallesi, Di Pretoro, Ballarini, Apone, Luporini et al.: A novel protein kinase from the ciliate Euplotes raikovi with close structural identity to the mammalian intestinal and male-germ cell kinases: characterization and functional implications in the ... in Protist 2010 (PubMed)

Weitere Antikörper gegen ICK Interaktionspartner

Human Intestinal Cell (MAK-Like) Kinase (ICK) Interaktionspartner

  1. These data identify ICK as an short rib polydactyly syndromes (SRPS)-associated gene and reveal that abnormalities in signalling pathways contribute to defective skeletogenesis

  2. findings suggest that increased ICK expression/activity in response to protein deprivation likely provides a novel protective mechanism to limit apoptosis and support compensatory mucosal growth under nutritional stress.

  3. the expressions of ICK/MAK (zeige MAK Antikörper)/MOK (zeige MOK Antikörper) proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

  4. In glioblastoma cells with deregulated high levels of CCRK (zeige CDK20 Antikörper), its depletion restores cilia through ICK and an ICK-related kinase MAK (zeige MAK Antikörper), thereby inhibiting glioblastoma cell proliferation.

  5. High ICK expression is associated with prostate cancer.

  6. an important role for ICK in modulating the activity of mTORC1 through phosphorylation of Raptor (zeige RPTOR Antikörper) Thr (zeige TRH Antikörper)-908.

  7. ICK may play a role in the development of multiple organ systems. R272Q has been associated with endocrine-cerebro-osteodysplasia and may explain loss of function since the R272Q mutant fails to localize at the nucleus and has diminished kinase activity

  8. ICK plays an important role in the regulation of proliferation and differentiation of intestinal epithelial cells. ICK may control G1 cell cycle progression by regulating expression of cell cycle regulators cyclin D1 (zeige CCND1 Antikörper), c-Myc (zeige MYC Antikörper) and p21Cip1 (zeige CDKN1A Antikörper).

  9. ICK and FBX9 (zeige FBXO9 Antikörper) are divergently transcribed from a bidirectional promoter that is GC-rich (zeige RELB Antikörper) and contains a CpG island.

  10. PP5 (protein phosphatase 5)and CCRK (cell cycle-related kinase (zeige CDK20 Antikörper)) are yin-yang regulators of T157 phosphorylation. ICK interacts with and phosphorylates human Scythe (zeige BAT3 Antikörper), an essential regulator of proliferation and apoptosis during mammalian development.

Mouse (Murine) Intestinal Cell (MAK-Like) Kinase (ICK) Interaktionspartner

  1. Data indicate an essential role for intestinal cell kinase (ICK) in lung development and advances the mechanistic understanding of endocrine-cerebro-osteodysplasia (ECO) syndrome.

  2. The results of this study found that loss of Ick leads to abnormal localization of the IFT component in kinocilia, PCP (zeige BMP1 Antikörper) defects in HCs (zeige HLCS Antikörper), and hearing dysfunction.

  3. findings suggest that increased ICK expression/activity in response to protein deprivation likely provides a novel protective mechanism to limit apoptosis and support compensatory mucosal growth under nutritional stress.

  4. the expressions of ICK/MAK (zeige MAK Antikörper)/MOK proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

  5. Data indicate that ciliary defects caused by a lack of functional intestinal cell kinase (ICK) leads to abnormal Sonic hedgehog (Shh (zeige SHH Antikörper)) signaling, resulting in congenital disorders such as endocrine-cerebro-osteodysplasia (ECO) syndrome .

  6. ICK is a Kif3a (zeige KIF3A Antikörper) kinase and essential for proper ciliogenesis in development by regulating ciliary transport at the tip of cilia.

  7. ICK and FBX9 (zeige FBXO9 Antikörper) are divergently transcribed from a bidirectional promoter that is GC-rich (zeige RELB Antikörper) and contains a CpG island.

ICK Antigen-Profil

Protein Überblick

Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.

Genbezeichner und Symbole assoziert mit ICK

  • intestinal cell (MAK-like) kinase (ICK) Antikörper
  • intestinal cell (MAK-like) kinase (ick) Antikörper
  • intestinal cell kinase (Ick) Antikörper
  • 2210420N10Rik Antikörper
  • AI848300 Antikörper
  • ECO Antikörper
  • ICK Antikörper
  • LCK2 Antikörper
  • Mrk Antikörper

Bezeichner auf Proteinebene für ICK

intestinal cell (MAK-like) kinase , intestinal cell kinase , serine/threonine-protein kinase ICK-like , MAK-related kinase , hICK , laryngeal cancer kinase 2 , serine/threonine protein kinase , serine/threonine-protein kinase ICK , mICK , MRK , heart serine-threonine protein kinase

GENE ID SPEZIES
421896 Gallus gallus
462772 Pan troglodytes
100014080 Monodelphis domestica
100056645 Equus caballus
100225015 Taeniopygia guttata
100401851 Callithrix jacchus
100451338 Pongo abelii
100498050 Xenopus (Silurana) tropicalis
100544019 Meleagris gallopavo
100552302 Anolis carolinensis
100582867 Nomascus leucogenys
22858 Homo sapiens
506286 Bos taurus
481843 Canis lupus familiaris
100511822 Sus scrofa
56542 Mus musculus
84411 Rattus norvegicus
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