Interleukin 4 Induced 1 Proteine (IL4I1)

IL4I1 encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. Zusätzlich bieten wir Ihnen Interleukin 4 Induced 1 Antikörper (29) und Interleukin 4 Induced 1 Kits (8) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
IL4I1 14204 O09046
IL4I1 259307 Q96RQ9
Ratte IL4I1 IL4I1 308575  
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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Hefe Bothrops insularis His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
1.920,64 €
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Hefe Bitis gabonica His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
1.953,81 €
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Hefe Crotalus durissus cascavella His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
1.955,55 €
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Hefe REACT_Vipera berus His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.035,88 €
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Hefe Kobra His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.056,83 €
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Hefe Bothrops atrox His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.128,41 €
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Hefe Ophiophagus hannah His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.169,05 €
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IL4I1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human ,
,

Weitere Proteine zu Interleukin 4 Induced 1 (IL4I1) Interaktionspartnern

Mouse (Murine) Interleukin 4 Induced 1 (IL4I1) Interaktionspartner

  1. IL4I1 promotes central nervous system remyelination and axonal integrity.

  2. our findings indicate that IL4I1 promotes an enhanced M2 functional phenotype.

  3. inhibits CD8 (zeige CD8A Proteine)+ antitumor T-cell response in vivo

  4. The H46 locus on chromosome 7 was found to encode the interleukin 4 (zeige IL4 Proteine)-induced IL4i1 gene.

Human Interleukin 4 Induced 1 (IL4I1) Interaktionspartner

  1. reviewed SNPs of the IL4I1 isoform 1, which is expressed in lymphoid tissue; the N92D SNP leads to a hyperactive enzyme, while the R102G mutation is hypomorphic; show that IL4I1 activity is not only directed against phenylalanine, as initially described, but also at a lower level against arginine

  2. The immunosuppressive enzyme IL4I1 expressed differentially in human induced Aiolos (zeige IKZF3 Proteine)+, but not natural Helios (zeige ZNFN1A2 Proteine)+, FOXP3 (zeige FOXP3 Proteine)+ Treg cells.

  3. IL4I1 upregulation in human Th17 cells limits their TCR-mediated expansion not only by blocking the molecular pathway involved in the activation of the IL-2 promoter, but also by maintaining high levels of Tob1, which impairs entry into the cell cycle.

  4. IL4I1 plays a distinct role compared to other antibacterial enzymes produced by mononuclear phagocytes.

  5. participates in the downregulation of Th1 (zeige TH1L Proteine) inflammation

  6. hIL4I1 inhibited the proliferation of CD3 (zeige CD3 Proteine)-stimulated T lymphocytes with a similar effect on CD4 (zeige CD4 Proteine)(+) and CD8 (zeige CD8A Proteine)(+) T cells. In contrast, memory T cells were more strongly affected by hIL4I1 and its catabolite H(2)O(2) than naive T cells

  7. strong IL4I1 expression is associated with B-cell lymphomas.

Interleukin 4 Induced 1 (IL4I1) Protein Überblick

Protein Überblick

This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit IL4I1

  • interleukin 4 induced 1 (IL4I1)
  • antimicrobial protein escapin precursor (LOC100533346)
  • interleukin 4 induced 1 (Il4i1)
  • RIKEN cDNA 4930438A08 gene (4930438A08Rik)
  • Escapin Protein
  • FIG1 Protein
  • Fig1-ps Protein
  • LAAO Protein
  • LAO Protein

Bezeichner auf Proteinebene für IL4I1

interleukin 4 induced 1 , L-amino-acid oxidase , IL4-induced protein 1 , L-amino acid oxidase , interleukin-4-induced protein 1 , interleukin-four induced gene 1 , interleukin-four induced gene-1 protein , interleukin-four induced protein-1 , protein Fig-1 , Fig-1 protein , interleukin four induced 1 , uncharacterized protein LOC73988

GENE ID SPEZIES
456223 Pan troglodytes
719114 Macaca mulatta
100533346 Aplysia californica
14204 Mus musculus
259307 Homo sapiens
484371 Canis lupus familiaris
100522257 Sus scrofa
308575 Rattus norvegicus
73988 Mus musculus
Ausgewählte Anbieter für Interleukin 4 Induced 1 Proteine (IL4I1)
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