anti-Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Antikörper

Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.. Zusätzlich bieten wir Ihnen HAPLN1 Proteine (10) und HAPLN1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
HAPLN1 1404 P10915
HAPLN1 12950 Q9QUP5
HAPLN1 29331  
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Top anti-HAPLN1 Antikörper auf antikoerper-online.de

Showing 10 out of 52 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-HAPLN1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: NCI-H226 cell lysate WB Suggested Anti-HAPLN1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: NCI-H226 cell lysate  HAPLN1 is strongly supported by BioGPS gene expression data to be expressed in Human NCI-H226 cells 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB HAPLN1 Antibody (N-term) (ABIN653748) western blot analysis in MCF-7,Jurkat,HepG2 cell line lysates (35 µg/lane).This demonstrates the HAPLN1 antibody detected the HAPLN1 protein (arrow). HAPLN1 Antibody (N-term) (ABIN653748) IHC analysis in formalin fixed and paraffin embedded prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the HAPLN1 Antibody (N-term)for immunohistochemistry. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Kaninchen Unkonjugiert FACS, IHC (p), WB   0.4 mL Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of HAPLN1 staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Immunohistochemical analysis of HAPLN1 staining in rat liver formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the an 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cell lines, using HAPLN1 antibody. Immunohistochemistry of paraffin-embedded rat liver using HAPLN1 antibody at dilution of 1:100 (x40 lens). 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Immunohistochemistry-Paraffin: HAPLN1 Antibody [NBP2-29953] - IHC analysis in formalin fixed and paraffin embedded prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the (N-term)for immunohistochemistry. Clinical relevance has not been evaluated. Flow Cytometry: HAPLN1 Antibody [NBP2-29953] - Flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 0.4 mL Anmelden zum Anzeigen 5 bis 8 Tage
311,00 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: HAPLN1 Antibody [NBP1-85443] - Staining of human bronchus shows strong cytoplasmic positivity in cartilage. Western Blot: HAPLN1 Antibody [NBP1-85443] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: HAPLN1 Antibody [NBP1-84376] - Staining of human bronchus shows strong positivity in cartilage. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert WB HAPLN1 antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
495,58 €
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HAPLN1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-HAPLN1 Antikörper

  1. Human Polyclonal HAPLN1 Primary Antibody für FACS, IHC (p) - ABIN653748 : Wheeler, Metter, Tanaka, Absher, Higgins, Zahn, Wilhelmy, Davis, Singleton, Myers, Ferrucci, Kim: Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. in PLoS genetics 2009 (PubMed)
    Zeige alle 3 Referenzen für 653748

  2. Cow (Bovine) Polyclonal HAPLN1 Primary Antibody für WB - ABIN2777097 : Seyfried, McVey, Almond, Mahoney, Dudhia, Day et al.: Expression and purification of functionally active hyaluronan-binding domains from human cartilage link protein, aggrecan and versican: formation of ternary complexes with defined hyaluronan ... in The Journal of biological chemistry 2005 (PubMed)

Weitere Antikörper gegen HAPLN1 Interaktionspartner

Zebrafish Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Interaktionspartner

  1. Hapln1a-ECM (zeige MMRN1 Antikörper) stabilizes the secreted growth factor (zeige WNT2 Antikörper) Semaphorin3d (Sema3d (zeige SEMA3D Antikörper)), which has been independently shown to mediate Cx43 (zeige GJA1 Antikörper) dependent phenotypes during regeneration.

  2. Hapln1a has a critical role in connexin43 (zeige GJA1 Antikörper)-dependent growth and patterning in the regenerating fin skeleton

  3. The cloning and characterization of crtl1 and its expression during embryogenesis are reported.

Cow (Bovine) Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Interaktionspartner

  1. stimulates proteoglycan (zeige Vcan Antikörper) and types II and IX collagens in intervertebral disc cells - stimulates synthesis of matrix molecules

Human Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Interaktionspartner

  1. CSGalNAcT-1 (zeige CSGALNACT1 Antikörper) and Hapln-1 may play important roles in the pathogenesis of Kashin-Beck disease and osteoarthritis.

  2. HAPLN1 is overexpressed in metastatic melanoma and is secreted exclusively by the tumor cells

  3. Single-nucleotide polymorphism in the hyaluronan and proteoglycan link protein 1 (HAPLN1) gene is associated with spinal osteophyte formation and disc degeneration in Japanese women.

  4. An in vitro model of perineuronal nets has been developed demonstrating that cartilage link protein (along with hyaluronan synthase) are necessary for their formation.

  5. link protein may function as a stabilizer of the interaction between aggrecan (zeige ACAN Antikörper) and hyaluronan in cartilage and between versican (zeige Vcan Antikörper) and hyaluronan in many tissues

  6. SOX9 (zeige SOX9 Antikörper) is a key regulator of CRTL1

  7. cLP (zeige CALML3 Antikörper) and versican (zeige Vcan Antikörper) did not bind directly to each other in solution yet formed ternary complexes with hyaluronan

  8. Overexpression of HAPLN1 and its SP-IgV domain increases tumorigenic properties of mesothelioma. Thus, targeting the SP-IgV domain may be one of the therapeutic approaches in cancer treatment.

Mouse (Murine) Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Interaktionspartner

  1. Aggrecan (zeige ACAN Antikörper), link protein and TN-R (zeige TNR Antikörper) were identified to be essential for the neuroprotective properties of the perineuronal net.

  2. Mef2c (zeige MEF2C Antikörper) regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart.

  3. our findings demonstrate that the formation of perineuronal nets triggered by neuronal Crtl1 synthesis is a key event in the diminuation of plasticity in the adult CNS

  4. there is a general and systemic function of link protein in the organization of extracellular matrix in a number of tissues, possibly interacting with other proteoglycans, such as versican (zeige Vcan Antikörper), brevican (zeige BCAN Antikörper), and neurocan (zeige NCAN Antikörper)

  5. Data suggest that the reported temporal co-expression of cartilage link protein and neurocan (zeige NCAN Antikörper) in developing brain implicates the possibility of a cooperative function of these molecules.

  6. reduced versican (zeige Vcan Antikörper) expression may contribute to a subset of the cardiac abnormalities observed in the Crtl1(-/-) mouse.

HAPLN1 Antigen-Profil

Protein Überblick

Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.

Genbezeichner und Symbole assoziert mit HAPLN1

  • hyaluronan and proteoglycan link protein 1 (HAPLN1) Antikörper
  • hyaluronan and proteoglycan link protein 1a (hapln1a) Antikörper
  • hyaluronan and proteoglycan link protein 1 (Hapln1) Antikörper
  • BB099155 Antikörper
  • CLP Antikörper
  • Crtl1 Antikörper
  • Crtl1l Antikörper
  • CTRL1 Antikörper
  • hapln1 Antikörper
  • LP Antikörper
  • LP-1 Antikörper
  • wu:fc26f11 Antikörper
  • wu:fc37g04 Antikörper
  • wu:fc50e12 Antikörper
  • wu:fc55h01 Antikörper

Bezeichner auf Proteinebene für HAPLN1

hyaluronan and proteoglycan link protein 1 , cartilage linking protein 1 , fc26f11 , fc37g04 , fc50e12 , fc55h01 , hyaluronan proteoglycan link protein 1 , cartilage link protein , cartilage-link protein , cartilage-linking protein 1 , proteoglycan link protein , Cartilage link protein , cartilage link protein 1 , link protein , LP , link protein precursor (AA -15 to 339)

GENE ID SPEZIES
461765 Pan troglodytes
488921 Canis lupus familiaris
493635 Danio rerio
712501 Macaca mulatta
100442758 Pongo abelii
100605865 Nomascus leucogenys
281717 Bos taurus
1404 Homo sapiens
12950 Mus musculus
29331 Rattus norvegicus
396475 Gallus gallus
100034208 Equus caballus
445513 Sus scrofa
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