Hyaluronan Binding Protein 2 Proteine (HABP2)

The protein encoded by HABP2 is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. Zusätzlich bieten wir Ihnen HABP2 Antikörper (41) und HABP2 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
HABP2 3026 Q14520
HABP2 292126 Q6L711
HABP2 226243 Q8K0D2
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Top HABP2 Proteine auf antikoerper-online.de

Showing 9 out of 17 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
Escherichia coli (E. coli) Human His-SUMO Tag   50 μg Anmelden zum Anzeigen 11 Days
$341.00
Details
Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$548.63
Details
Human Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$300.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,759.17
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,759.17
Details
Escherichia coli (E. coli) Human His tag   100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$640.00
Details

HABP2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, ,
Rat (Rattus)

Mouse (Murine)

Weitere Proteine zu Hyaluronan Binding Protein 2 (HABP2) Interaktionspartnern

Human Hyaluronan Binding Protein 2 (HABP2) Interaktionspartner

  1. Study showed that lower FSAP antigen plasma levels were associated with a higher chance of arterial recanalization after tissue plasminogen activator (zeige PLAT Proteine) treatment, suggesting an involvement of FSAP in tissue plasminogen activator (zeige PLAT Proteine)-induced clot (zeige TXNDC17 Proteine) lysis. FSAP antigen determination might be useful in predicting tissue plasminogen activator (zeige PLAT Proteine) response in stroke patients.

  2. HABP2 polymorphisms are not associated with thyroid cancer.

  3. the promoter activity, which could phenocopy changes in Habp2 mRNA in response to TGF-beta (zeige TGFB1 Proteine), was found to be located in the 177-bp region upstream of the transcription start site, and this region did not contain any SMAD (zeige SMAD1 Proteine) binding sites.

  4. Results show that G534E germline variant in HABP2 does not account for the familial nature of nonmedullary thyroid cancer in Australian kindreds but and is common in the general population.

  5. omology modeling suggested that the Glu (zeige DCTN1 Proteine)-221 side chain could sterically hinder insertion of the N terminus into the HABP2 protease domain, helping to explain the detrimental effects of Glu (zeige DCTN1 Proteine)-221 substitution on HABP2 activity.

  6. The data do not support the pathogenicity of the HABP2 c.1601G > A variant but highlight the existence of a new one that should be more extensively searched for in familial papillary thyroid carcinoma patients and its pathogenicity more carefully evaluated.

  7. No evidence supporting a role for the HABP2 G534E variant (SNP rs7080536) in papillary thyroid carcinoma.

  8. HABP2 G534E appears to be a susceptibility gene in a subgroup of Familial Non-Medullary Thyroid Cancer (FNMTC), providing important diagnostic implications for this hereditary thyroid cancer.

  9. HABP2, which encodes an extracellular serine protease involved in coagulation, fibrinolysis, and inflammatory pathways, may be a genetic susceptibility locus for early-onset stroke. [Meta-Analysis]

  10. Patients with Gram-negative sepsis caused by B. pseudomallei have abundant FSAP activation, which significantly correlates with stage of disease.

Mouse (Murine) Hyaluronan Binding Protein 2 (HABP2) Interaktionspartner

  1. the promoter activity, which could phenocopy changes in Habp2 mRNA in response to TGF-beta (zeige TGFB1 Proteine), was found to be located in the 177-bp region upstream of the transcription start site, and this region did not contain any SMAD (zeige SMAD1 Proteine) binding sites.

  2. Lack of endogenous FSAP impaired the formation of stable, occlusive thrombi in mice.

  3. Results show that the lack of FSAP in mice worsens the outcome of stroke; in the absence of FSAP there was a stronger inflammatory response and lower cell survival due to insufficient activation of the PI3K/AKT (zeige AKT1 Proteine) pathway

  4. Lower FSAP expression is associated with enhanced liver fibrosis and inflammation in patients with chronic hepatic disorders and murine experimental liver injury.

  5. Data indicate that FSAP mediates proteolytic cleavage and activation of bone morphogenetic protein-2 (BMP-2 (zeige BMP2 Proteine)).

  6. Hyaluronic acid binding protein 2 (HABP2) negatively regulates vascular integrity via activation of protease-activated receptor/RhoA (zeige RHOA Proteine)/Rho kinase (zeige ROCK2 Proteine) signaling. It represents a potential therapeutic target for syndromes of increased vascular permeability.

HABP2 Protein Überblick

Protein Überblick

The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit HABP2

  • hyaluronan binding protein 2 (HABP2)
  • hyaluronan binding protein 2 (habp2)
  • hyaluronan binding protein 2 (Habp2)
  • hyaluronic acid binding protein 2 (Habp2)
  • AI035669 Protein
  • Fsap Protein
  • Habp Protein
  • habp2 Protein
  • HGFAL Protein
  • Phbp Protein

Bezeichner auf Proteinebene für HABP2

hyaluronan binding protein 2 , hyaluronan-binding protein 2-like , factor VII activating protein , factor VII-activating protease , factor seven-activating protease , hepatocyte growth factor activator-like protein , hyaluronan-binding protein 2 , hyaluronic acid binding protein 2 , plasma hyaluronan binding protein , plasma hyaluronan-binding protein , hyaduronic acid-binding protein 2

GENE ID SPEZIES
423898 Gallus gallus
450744 Pan troglodytes
477822 Canis lupus familiaris
548376 Xenopus (Silurana) tropicalis
697495 Macaca mulatta
100068293 Equus caballus
100223786 Taeniopygia guttata
100407842 Callithrix jacchus
100461891 Pongo abelii
100472238 Ailuropoda melanoleuca
100591352 Nomascus leucogenys
3026 Homo sapiens
507993 Bos taurus
292126 Rattus norvegicus
226243 Mus musculus
Ausgewählte Anbieter für HABP2 Proteine (HABP2)
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