Hook Homolog 1 (Drosophila) Proteine (HOOK1)

HOOK1 encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. Zusätzlich bieten wir Ihnen Hook Homolog 1 (Drosophila) Antikörper (67) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
HOOK1 77963 Q8BIL5
Ratte HOOK1 HOOK1 313370  
HOOK1 51361 Q9UJC3
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Top Hook Homolog 1 (Drosophila) Proteine auf antikoerper-online.de

Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$11,073.30
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$11,073.30
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
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HOOK1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , ,
, ,

Weitere Proteine zu Hook Homolog 1 (Drosophila) (HOOK1) Interaktionspartnern

Mouse (Murine) Hook Homolog 1 (Drosophila) (HOOK1) Interaktionspartner

  1. Single-molecule motility assays using total internal reflection fluorescence microscopy indicate that both Hook1 and Hook3 effectively activate cytoplasmic dynein, inducing longer run lengths and higher velocities than the previously characterized dynein activator bicaudal D2 (BICD2).

  2. azh mutation is due to a deletion of exons 10 and 11 in the murine Hook1 gene leading to a non-functional protein. Our results indicate that loss of Hook1 function results in ectopic positioning of microtubular structures within the spermatid

  3. Hook1 and Ankyrin G are co-locolized, Hook1 also localizes to additional regions of the cell devoid of Ankyrin G where it interacts with other proteins.

  4. Multiple samples of ejaculated spermatozoa from normal fertile C57BL/6 and infertile Hook1/Hook1 (formerly known as azh/azh) mutant males from uteri after mating.

Human Hook Homolog 1 (Drosophila) (HOOK1) Interaktionspartner

  1. Hook1 knockdown promoted epithelial-mesenchymal transition and attenuated the sensitivity of hepatocellular carcinoma cells to doxorubicin. In summary, our results indicate that downregulation of Hook1 plays a pivotal role in hepatocellular carcinoma progression via epithelial-mesenchymal transition. Hook1 may be used as a novel marker and therapeutic molecular target in hepatocellular carcinoma

  2. Single-molecule motility assays using total internal reflection fluorescence microscopy indicate that both Hook1 and Hook3 effectively activate cytoplasmic dynein, inducing longer run lengths and higher velocities than the previously characterized dynein activator bicaudal D2 (BICD2).

  3. SHP2 (zeige PTPN11 Proteine) positively regulates TGFbeta1 (zeige TGFB1 Proteine)-induced epithelial-mesenchymal transition modulated by its novel interacting protein Hook1.

  4. Hook1, a microtubule- and cargo-tethering protein, recognized the cytoplasmic tail of CD147 to help sort it and CD98 (zeige SLC3A2 Proteine) into Rab22a (zeige RAB22A Proteine)-dependent tubules associated with recycling.

  5. novel interactions between the microtubule-binding Hook1 and the large family of Rab (zeige HRB Proteine) GTPases also suggest a link between CLN3 (zeige CLN3 Proteine) function, microtubule cytoskeleton and endocytic membrane trafficking

  6. These data suggest that the FTS/Hook/FHIP complex functions to promote vesicle trafficking and/or fusion via the homotypic vacuolar protein sorting complex.

Hook Homolog 1 (Drosophila) (HOOK1) Protein Überblick

Protein Überblick

This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.

Genbezeichner und Symbole assoziert mit HOOK1

  • hook microtubule tethering protein 1 (HOOK1)
  • hook microtubule-tethering protein 1 (hook1)
  • hook microtubule tethering protein 1 (Hook1)
  • hook microtubule-tethering protein 1 (Hook1)
  • A930033L17Rik Protein
  • azh Protein
  • HK1 Protein
  • HOOK1 Protein
  • si:dkey-183n20.14 Protein

Bezeichner auf Proteinebene für HOOK1

hook homolog 1 (Drosophila) , protein Hook homolog 1 , abnormal spermatozoon head shape , mHK1 , h-hook1 , hHK1 , hook homolog 1

GENE ID SPEZIES
456895 Pan troglodytes
570393 Danio rerio
77963 Mus musculus
424675 Gallus gallus
479553 Canis lupus familiaris
100525467 Sus scrofa
313370 Rattus norvegicus
51361 Homo sapiens
785042 Bos taurus
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