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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Zusätzlich bieten wir Ihnen HOXA10 Kits (8) und HOXA10 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 71 products:
Mouse (Murine) Polyclonal HOXA10 Primary Antibody für WB - ABIN1881425
Gordon, Hassan, Saini, Montecino, van Wijnen, Stein, Stein, Lian: Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors. in Molecular and cellular biology 2010
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Dog (Canine) Polyclonal HOXA10 Primary Antibody für IHC, WB - ABIN2792574
Akbas, Song, Taylor: A HOXA10 estrogen response element (ERE) is differentially regulated by 17 beta-estradiol and diethylstilbestrol (DES). in Journal of molecular biology 2004
Show all 2 Pubmed References
Dog (Canine) Polyclonal HOXA10 Primary Antibody für WB - ABIN2792575
Sugimoto, Nakamura, Okinaka, Hirano, Ono, Shigeno, Shinjo, Ohnishi: HOXA10 expression induced by Abl kinase inhibitors enhanced apoptosis through PI3K pathway in CML cells. in Leukemia research 2008
These results suggest that downregulation of HOXA10 in the decidual cells promotes the expression of a cascade in the trophoblast cells, leading to an increase in matrix metalloproteinases to facilitate invasion.
Endometrial expression of HOXA10 and E-cadherin (zeige CDH1 Antikörper) are reduced in women with recurrent implantation failure and recurrent miscarriage.
Reduced expression of HOXA10 is associated with Hydrosalpinx.
To summarize, significant differential methylation of HOXA10 and COMT (zeige COMT Antikörper) promoter regions was found between the ectopic and eutopic endometrial tissues. This is the first study investigating the methylation of HOXA10 and COMT (zeige COMT Antikörper) genes and their linkage to endometriosis in Chinese patients.
using both knockdown and knockout approaches we show that Hottip expression is required for activation of the 5' Hoxa genes (Hoxa13 (zeige HOXA13 Antikörper) and Hoxa10/11) and for retaining Mll1 at the 5' end of Hoxa. Moreover, we demonstrate that artificially inducing Hottip expression is sufficient to activate the 5' Hoxa genes and that Hottip RNA binds to the 5' end of Hoxa
HOXA10 is overexpressed in oral squamous cell carcinoma (OSCC) and its expression is functionally associated with several important biological processes related to oral tumorigenesis, such as proliferation, migration and invasion.
The results demonstrated that mutation in HOXA10 gene contributes to the pathogenesis of cryptorchidism, but may not be a common cause.
The HOXA10 gene in women with endometriosis was hypomethylated compared to controls.
HOXA10 was expressed at a high level in the K562/ADM (zeige ADM Antikörper) cells, and knockdown of HOXA10 enhances the sensitivity of the K562/ADM (zeige ADM Antikörper) cells to cytotoxic killing by the therapeutic drug, ADR (zeige AKR1B1 Antikörper), as a result of the increased intracellular accumulation of ADR (zeige AKR1B1 Antikörper).
Regulated HOXA10 and HOXA11 (zeige HOXA11 Antikörper) expression is necessary for endometrial receptivity; decreased HOXA10 or HOXA11 (zeige HOXA11 Antikörper) expression leads to decreased implantation rates. Alternation of HOXA10 and HOXA11 (zeige HOXA11 Antikörper) expression has been identified as a mechanism of the decreased implantation associated with endometriosis, polycystic ovarian syndrome, leiomyoma, polyps, adenomyosis, and hydrosalpinx.
These results suggest that progesterone receptor (zeige PGR Antikörper) overexpression in endometrial stromal cells, likely due to high progesterone levels, triggers cyclin D3 (zeige CCND3 Antikörper) and Hoxa-10 overexpression, which may be involved in the pathological mechanisms of the mouse uterine decidual reaction.
Hmgn5 (zeige HMGN5 Antikörper) might act downstream of Hoxa10 to regulate the expression of Cox-2 (zeige COX2 Antikörper), Vegf (zeige VEGFA Antikörper) and Mmp2 (zeige MMP2 Antikörper).
Our results suggest that NA10HD increases the number of gamma-globin-transduced HSCs that engraft, leading to an elevated number of fetal hemoglobin-containing red cells.
we suggest that proper regional decidualization and polyploidy development requires FoxM1 (zeige FOXM1 Antikörper) signaling downstream of Hoxa10 and cyclin D3 (zeige CCND3 Antikörper).
these studies demonstrate a previously undescribed role for HoxA10 in terminating emergency granulopoiesis, suggesting an important contribution by Hox (zeige MSH2 Antikörper) proteins to the innate immune response.
Hoxa10 cooperates with Nkx2-5 (zeige NKX2-5 Antikörper) to regulate the timing of cardiac mesoderm differentiation.
results show that reduced APC (zeige APC Antikörper) activity is sufficient to induce formation of epithelial inclusion cysts and support ovarian endometrioid adenocarcinoma development and suggest that induced HOXA10 expression and loss of PTEN (zeige PTEN Antikörper) are key mechanisms driving endometrioid histotype differentiation and progression
a molecular mechanisms through which increased expression of HoxA10 increases Cdx4 expression by direct CDX4 activation and by Fgf2 (zeige FGF2 Antikörper)-induced beta-catenin (zeige CTNNB1 Antikörper) activity. This results in Cdx4-induced HoxA10-expression, creating a positive feedback mechanism
Setbp1 (zeige SETBP1 Antikörper) promotes the self-renewal of murine myeloid progenitors via activation of Hoxa9 (zeige HOXA9 Antikörper) and Hoxa10.
found that increased Fgf2 (zeige FGF2 Antikörper) production by HoxA10-overexpressing myeloid progenitor cells induced a phosphoinositol 3-kinase-dependent increase in beta-catenin (zeige CTNNB1 Antikörper) protein
study identified an E(2)/P(4) response element of the porcine HOXA10 gene for the first time
investigation of regulation of HOXA10 gene expression by estradiol and/or progesterone in porcine endometrium during estrous.
Homeobox A10 expression in the porcine endometrium is closely related to the implantation process and stimulated by conceptus products.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 (HOXA9) gene.
homeo box A10
, homeobox protein 1H
, homeobox protein HOXA10
, homeobox protein Hox-1.8
, homeobox protein Hox-1H
, homeobox protein Hox-A10
, homeobox protein A10
, homeobox A10
, homeobox A10, isoform 1
, homeobox protein Hox-A10-like
, homeo box A9
, homeo box A10b
, homeobox gene A-10
, homeobox protein Hox-A10b
, homeobox A11
, homeobox protein Hox-A11
, homeobox protein Hox-A11-like