Holocytochrome C Synthase Proteine (HCCS)

The protein encoded by HCCS is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Zusätzlich bieten wir Ihnen Holocytochrome C Synthase Antikörper (83) und Holocytochrome C Synthase Kits (17) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
HCCS 3052 P53701
Ratte HCCS HCCS 317444  
HCCS 15159 P53702
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Top Holocytochrome C Synthase Proteine auf antikoerper-online.de

Showing 7 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
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Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,713.33
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,718.83
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Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$672.00
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HCCS Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , ,
Mouse (Murine)

Weitere Proteine zu Holocytochrome C Synthase (HCCS) Interaktionspartnern

Human Holocytochrome C Synthase (HCCS) Interaktionspartner

  1. Data suggest that although HCCS mediates heme attachment to N-terminal cysteine in heme-attachment site (CXXXH) of cytochrome C (zeige CYCS Proteine) variants, up to 50% of cytochrome C (zeige CYCS Proteine) produced is modified in an oxygen-dependent manner, resulting in a mixed population of cytochrome c (zeige CYCS Proteine). [HCCS = holocytochrome c synthase]

  2. Bacterial cyt c (zeige CYCS Proteine) biogenesis pathways (Systems I and II) appear to recognize simply the CXXCH motif, not requiring alpha helix-1. Results here explain mechanistically how HCCS (System III) requires an extended region adjacent to CXXCH for maturation.

  3. cysteines and histidine of the heme attachment site, Cys (zeige DNAJC5 Proteine)-XX-Cys (zeige DNAJC5 Proteine)-His play a key role in mitochondrial holocytochrome c synthase

  4. These data indicate that heme contacts mediated by residues within these domains modulate the dynamics of heme binding and contribute to the stability of the HCCS-heme-cytochrome c (zeige CYCS Proteine) steady state ternary complex.

  5. Identification of a deletion in two patients, including HCCS, leads to the diagnosis of microphthalmia with linear skin defects syndrome

  6. Spectroscopic analyses of HCCS alone and complexes of HCCS with site-directed variants of cytochrome c (zeige CYCS Proteine) revealed the fundamental steps of heme attachment and maturation.

  7. Through the study of genetically engineered mice, the loss of HCCS is demonstrated to cause the male lethality of microphthalmia with linear skin defects (MLS) syndrome.

  8. mutant proteins (R217C and Delta 197-268) were unable to complement a Saccharomyces cerevisiae mutant deficient for the HCCS orthologue Cyc3p, in contrast to wild-type HCCS

  9. Missense mutation p.E159K of HCCS, leading to loss-of-function of encoded holocytochrome c-type synthase, in female with microphthalmia of both eyes and bilateral sclerocornea may suggest HCCS as candidate for severe ocular manifestations.

Mouse (Murine) Holocytochrome C Synthase (HCCS) Interaktionspartner

  1. Analysis of Mid1 (zeige MID1 Proteine), Hccs, Arhgap6 (zeige ARHGAP6 Proteine), and Msl3l1 (zeige MSL3 Proteine) in X-linked polydactyly (Xpl) and Patchy-fur (Paf (zeige KIAA0101 Proteine)) mutant mice

Holocytochrome C Synthase (HCCS) Protein Überblick

Protein Überblick

The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit HCCS

  • holocytochrome c synthase b (hccsb)
  • holocytochrome c synthase (hccs)
  • cytochrome c heme-lyase (cchl)
  • holocytochrome c synthase (HCCS)
  • holocytochrome c synthase (Hccs)
  • cytochrome c-type heme lyase (LOC100356413)
  • holocytochrome c synthetase (Hccs)
  • CCHL Protein
  • DDBDRAFT_0217711 Protein
  • DDBDRAFT_0266707 Protein
  • DDB_0217711 Protein
  • DDB_0266707 Protein
  • hccsb Protein
  • id:ibd1278 Protein
  • MCOPS7 Protein
  • RGD1563855 Protein
  • wu:fb18h01 Protein
  • wu:fc64e12 Protein
  • wu:fi43e01 Protein

Bezeichner auf Proteinebene für HCCS

cytochrome c-type heme lyase , holocytochrome c synthetase b , holocytochrome c synthase (cytochrome c heme-lyase) , holocytochrome c synthase , cytochrome c heme-lyase , holocytochrome c-type synthase , holocytochrome c synthetase , CCHL

GENE ID SPEZIES
58016 Danio rerio
448226 Xenopus (Silurana) tropicalis
8620147 Dictyostelium discoideum AX4
3052 Homo sapiens
317444 Rattus norvegicus
506250 Bos taurus
424482 Gallus gallus
480834 Canis lupus familiaris
100356413 Oryctolagus cuniculus
15159 Mus musculus
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