anti-Hect Domain and RLD 5 (HERC5) Antikörper

HERC5 is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Zusätzlich bieten wir Ihnen Hect Domain and RLD 5 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
HERC5 51191 Q9UII4
HERC5 514373  
HERC5 100063774  
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Top anti-Hect Domain and RLD 5 Antikörper auf antikoerper-online.de

Showing 10 out of 14 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-HERC5 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HT1080 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-HERC5 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$676.50
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$298.57
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$433.13
Details
Human Kaninchen Unkonjugiert WB HERC5 antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details
Human Kaninchen Unkonjugiert WB HERC5 antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry-Paraffin: HERC5 Antibody [NBP1-91985] Staining of human testis shows strong cytoplasmic positivity in the spermatogonia. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Western Blot: HERC5 Antibody [NBP1-58102] - Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysate Western Blot: HERC5 Antibody [NBP1-58102] - hek293 cell lysate at 1:1000. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details
Human Kaninchen Unkonjugiert IHC (p), WB   50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$676.50
Details

HERC5 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human ,
,

Cow (Bovine)


Horse (Equine)


Am meisten referenzierte anti-Hect Domain and RLD 5 Antikörper

  1. Human Polyclonal HERC5 Primary Antibody für ELISA, WB - ABIN565561 : Woods, Kelly, Hattlmann, Tong, Xu, Coleman, Quest, Smiley, Barr: Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag. in Retrovirology 2011 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen Hect Domain and RLD 5 Interaktionspartner

Human Hect Domain and RLD 5 (HERC5) Interaktionspartner

  1. HERC5 plays a crucial role in HCC (zeige FAM126A Antikörper) immune evasion and has clinical relevance as a reproducible prognostic marker for risk of tumor recurrence and survival in patients.

  2. The inhibitory effect of ISG15 (zeige ISG15 Antikörper) on HCV RNA replication does not require its conjugation to substrates by HERC5.

  3. vIRF1 association with HERC5 altered ISG15 (zeige ISG15 Antikörper) modification of cellular proteins, and knockdown of ISG15 (zeige ISG15 Antikörper) augmented reactivation of KSHV from latency.

  4. The study reports on the NMR solution structure of a G-quadruplex formed by the CEB1 DNA G-rich fragment d(AGGGGGGAGGGAGGGTGG), harboring several G-tracts including one with six continuous guanines.

  5. Results show that HERC5 gene may be involved in regulating the spread of non-small cell lung cancer tumors where the methylation of its promoter is correlated with number increase of disseminated tumor cells and metastases as well as survival decreased.

  6. Authors identified a second distinct mechanism by which HERC5 inhibits HIV-1 replication and demonstrate that HERC5 is evolving under strong positive selection.

  7. Data indicate that income was inversely related to smoking behavior, and paternally derived CEB1 mutations were dose dependently increased when the father smoked in the 6 mo before pregnancy, 0.21 vs. 0.05 in smoking and nonsmoking fathers, respectively.

  8. The E3 ligase activity of HERC5 was required for blocking HIV-1 Gag particle production and correlated with the post-translational modification of Gag with ISG15 (zeige ISG15 Antikörper).

  9. This study characterizes HERC5 as a positive regulator of innate antiviral responses, and show that it sustains IRF3 (zeige IRF3 Antikörper) activation via a novel posttranslational modification, ISG15 (zeige ISG15 Antikörper)-ylation.

  10. Data show that HERC5, a functionally active HECT ubiquitin ligase, exhibits a tightly controlled cytosolic level under inflammatory conditions in endothelial cells.

Hect Domain and RLD 5 (HERC5) Antigen-Profil

Protein Überblick

This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.

Genbezeichner und Symbole assoziert mit HERC5

  • HECT and RLD domain containing E3 ubiquitin protein ligase 5 (HERC5) Antikörper
  • hect domain and RLD 5 (HERC5) Antikörper
  • CEB1 Antikörper
  • CEBP1 Antikörper
  • HERC5 Antikörper

Bezeichner auf Proteinebene für HERC5

E3 ISG15--protein ligase HERC5 , hect domain and RLD 5 , probable E3 ubiquitin-protein ligase HERC5-like , HECT domain and RCC1-like domain-containing protein 5 , cyclin-E-binding protein 1 , probable E3 ubiquitin-protein ligase HERC5

GENE ID SPEZIES
514373 Bos taurus
461369 Pan troglodytes
478474 Canis lupus familiaris
100063774 Equus caballus
100410536 Callithrix jacchus
100438710 Pongo abelii
100480303 Ailuropoda melanoleuca
100584608 Nomascus leucogenys
51191 Homo sapiens
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