Heat Shock 70kDa Protein 4 Proteine (HSPA4)

heat shock protein\; may have an important role following forebrain ischemia and may allow astrocytes to protect neurons [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen Heat Shock 70kDa Protein 4 Antikörper (117) und Heat Shock 70kDa Protein 4 Kits (21) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
HSPA4 3308 P34932
HSPA4 15525  
Ratte HSPA4 HSPA4 266759 O88600
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Showing 6 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$11,073.30
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$11,073.30
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$669.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
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Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$866.25
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HSPA4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , ,
Mouse (Murine)

Weitere Proteine zu Heat Shock 70kDa Protein 4 (HSPA4) Interaktionspartnern

Human Heat Shock 70kDa Protein 4 (HSPA4) Interaktionspartner

  1. verified the interaction of cellular chaperon HSP70 (zeige HSP70 Proteine) with Porcine reproductive and respiratory syndrome virus NSP12, and demonstrated that NSP12 could recruit HSP70 (zeige HSP70 Proteine) to maintain its own stability and benefit for the virus replication

  2. Modulatory action of extracellular HSP70 (zeige HSP70 Proteine) on A549 inflammatory response through RAGE (zeige AGER Proteine) was able to evoke important expression changes in monocyte, showing its relevance in influencing the interaction between cancer and immune system cell.

  3. Here the authors show that in budding yeast, Hsf1 (zeige HSF1 Proteine) basally associates with the chaperone Hsp70 (zeige HSP70 Proteine) and this association is transiently disrupted by heat shock, providing the first evidence that a chaperone repressor directly regulates Hsf1 (zeige HSF1 Proteine) activity.

  4. Pharmacological or genetic activation of heat shock protein 70 (Hsp70 (zeige HSP70 Proteine)) protects against loss of parkin (zeige PARK2 Proteine) Function. Heat shock protein members may act as compensatory factors for parkin (zeige PARK2 Proteine) loss of function and that the exploitation of these factors may be of potential therapeutic value.

  5. targeting the Hsp70 (zeige HSP70 Proteine) induction in Hsp90 (zeige HSP90 Proteine) inhibitor-treated cancer cells and tumor vasculature cells may beneficially enhance the radiosensitizing effect

  6. The interaction of Fas receptor (zeige FAS Proteine) with FasL (zeige FASL Proteine) leads to an activation of the Tag7 (zeige PGLYRP1 Proteine)-Hsp70 (zeige HSP70 Proteine) complex in the lymphocyte membrane fraction, and here FasL (zeige FASL Proteine) acts as a receptor that induces intracellular signaling in lymphocytes.An interaction of the MicA (zeige MICA Proteine) stress ligand with the NKG2D (zeige KLRK1 Proteine) receptor is necessary for the release of this cytotoxic complex

  7. Triptolide downregulates Sp1 (zeige PSG1 Proteine) and HSP70 (zeige HSP70 Proteine) mRNA in gastric cancer cell lines.

  8. HSP70 (zeige HSP70 Proteine)-TRIM32 (zeige TRIM32 Proteine) complex is biochemically distinct from the previously characterized 14-3-3 (zeige YWHAQ Proteine)-TRIM32 (zeige TRIM32 Proteine) phospho-complex.

  9. There is overwhelming evidence that molecular chaperones such as Hsp27 (zeige HSPB1 Proteine), Hsp70 (zeige HSP70 Proteine) and Hsp90 (zeige HSP90 Proteine) are expressed at elevated levels in a wide range of cancers by stabilizing the mutated neoplasm proteins. (Review)

  10. HSP70 (zeige HSP70 Proteine) is required for the maintenance of a functional mitotic centrosome that supports the assembly of a bipolar mitotic spindle.

Mouse (Murine) Heat Shock 70kDa Protein 4 (HSPA4) Interaktionspartner

  1. Data show that heat shock protein 70 (HSP70 (zeige HSP70 Proteine)) induction by geranylgeranylacetone (GGA) was effective against N-methyl-N-nitrosourea (MNU-induced photoreceptor cell loss.

  2. Upregulation of HSPA4 would control apoptosis of inflammatory cells and immune response in the gut (zeige GUSB Proteine), which might develop treatment resistance in inflammatory bowel disease.

  3. regulates the expression of SDF-1 (zeige CXCL12 Proteine) and Twist in fibroblasts, thereby controlling gastric ulcer healing

  4. Inhibition of Apg-2 by shRNA not only decreased cell proliferation, but also induced cell apoptosis in BCR/ABL (zeige ABL1 Proteine) positive chronic myeloid leukemia (zeige BCL11A Proteine) cells (BaF3-BCR/ABL (zeige ABL1 Proteine), BaF3-BCR/ABL (zeige ABL1 Proteine)(T315I)).

  5. PSMB8 (zeige PSMB8 Proteine), ALDH1A1 (zeige ALDH1A1 Proteine), and HSPA4 were identified to be located in ovarian tissues, to regulate 12 cellular pathways, and demonstrate age-dependent dynamic changes in expression profiling.

  6. HSPA4L (zeige HSPA4L Proteine) and HSPA4 collaborate in embryonic lung maturation, which is necessary for adaptation to air breathing at birth.

  7. study demonstrates that lack of HSPA4 leads to cardiac hypertrophy and fibrosis; data reveal the distinct, non-redundant role of HSPA4 in the protein quality control that maintains the proper protein folding and homeostasis in cardiomyocytes

  8. Data suggest HSPA4 is required for spermatogenesis. All homozygous HSPA4-deficient mice are apparently healthy; HSPA4 is expressed as early as E13.5 in male gonad; increased number of HSPA4-deficient males are infertile, whereas females are fertile.

  9. Findings provide in vivo evidence that Hsp110 (zeige HSPH1 Proteine) plays a critical function in tau phosphorylation state through maintenance of efficient PP2A (zeige PPP2R2B Proteine) activity, confirming its role in pathogenesis of Alzheimer's disease and other tauopathies.

  10. Overexpression of Apg-2 in proB-BCR/ABL (zeige ABL1 Proteine) cells increases cell proliferation and protects cells from oxidative damage.

Zebrafish Heat Shock 70kDa Protein 4 (HSPA4) Interaktionspartner

  1. Expression of hspa4a and hspa4b are up-regulated in the inflamed gut (zeige GUSB Proteine) in a manner similar to that previously observed in mammals.

Heat Shock 70kDa Protein 4 (HSPA4) Protein Überblick

Protein Überblick

heat shock protein\; may have an important role following forebrain ischemia and may allow astrocytes to protect neurons

Genbezeichner und Symbole assoziert mit HSPA4

  • heat shock protein family A (Hsp70) member 4 (HSPA4)
  • heat shock protein family A (Hsp70) member 4 S homeolog (hspa4.S)
  • heat shock protein 4 (Hspa4)
  • heat shock protein family A member 4 (Hspa4)
  • heat shock protein 4b (hspa4b)
  • 70kDa Protein
  • AI317151 Protein
  • APG-2 Protein
  • HS24/P52 Protein
  • Hsp70 Protein
  • Hsp70RY Protein
  • Hsp110 Protein
  • hspa4 Protein
  • hspa4-a Protein
  • HSPH2 Protein
  • irp94 Protein
  • mKIAA4025 Protein
  • osp94 Protein
  • pg-2 Protein
  • RY Protein
  • wu:fi30e11 Protein
  • zgc:55743 Protein
  • zgc:77413 Protein

Bezeichner auf Proteinebene für HSPA4

heat shock 70 kDa protein 4 , heat shock 70-related protein APG-2 , heat shock 70kD protein 4 , heat shock protein, 110 kDa , hsp70 RY , heat shock protein Apg-2 , ischemia responsive 94 kDa protein , heat shock protein 4

GENE ID SPEZIES
100171909 Pongo abelii
398863 Xenopus laevis
416339 Gallus gallus
3308 Homo sapiens
474680 Canis lupus familiaris
536558 Bos taurus
100524853 Sus scrofa
15525 Mus musculus
266759 Rattus norvegicus
334086 Danio rerio
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