anti-Growth Differentiation Factor 1 (GDF1) Antikörper

GDF1 encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. Zusätzlich bieten wir Ihnen GDF1 Kits (51) und GDF1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GDF1 2657 P27539
GDF1 14559 P20863
GDF1 306351  
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Top anti-GDF1 Antikörper auf antikoerper-online.de

Showing 10 out of 65 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of GDF1 Antibody (N-term) (ABIN388816) in HepG2 cell line lysates (35 µg/lane). GDF1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with GDF1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
387,62 €
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Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of GDF1 expression in U87MG (A), HeLa (B), Raw264.7 (C), H9C2 (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Human, Small Intestine: Formalin-Fixed Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Maus Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
342,86 €
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Ratte Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
361,90 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
513,33 €
Details

GDF1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Weitere Antikörper gegen GDF1 Interaktionspartner

Human Growth Differentiation Factor 1 (GDF1) Interaktionspartner

  1. Rare inherited and de novo variants in 2,871 congenital heart disease probands identified GDF1, MYH6 (zeige MYH6 Antikörper), and FLT4 (zeige FLT4 Antikörper) as causative genes.

  2. Our results suggest that the GDF1 rs4808863 polymorphism contributes to an increased risk of fetal CHDs, especially the subtypes of AVSD, LVOTO and left-right laterality defects.

  3. This implies that Gdf1 potentiates Nodal activity by stabilizing a low molecular weight fraction that is susceptible to neutralization by soluble Acvr2 (zeige ACVR2A Antikörper).

  4. indicate that the expression of growth/differentiation factor 1 (GDF1) is up-regulated in human dilated cardiomyopathy (DCM)hearts and murine hypertrophic hearts.

  5. GDF1 may be associated with congenital heart defects risk, and these variations contribute at least in part to the development of some subtypes of conotruncal defects in the Chinese Han population.

  6. Molecular genetic basis of a kindred with 5 siblings with right atrial isomerism involved mutations in GDF1.

  7. Heterozygous loss-of-function mutations in the human GDF1 gene contribute to cardiac defects ranging from tetralogy of Fallot to transposition of the great arteries.

  8. GDF1 expression is correlated with progression and aggressive behaviors in cervical cancer, suggesting a tumor-promoting role for GDF1 in the progression of this malignancy.

Mouse (Murine) Growth Differentiation Factor 1 (GDF1) Interaktionspartner

  1. Epigenetic silencing of GDF1 abrogates the growth-inhibitory SMAD (zeige SMAD1 Antikörper) signaling and renders proliferation advantage to gastric epithelial cells during carcinogenesis

  2. GDF1 in the heart is a novel mediator that protects against the development of post-infarction cardiac remodelling via negative regulation of the MEK (zeige MDK Antikörper)-ERK1/2 (zeige MAPK1/3 Antikörper) and Smad (zeige SMAD1 Antikörper) signalling pathways.

  3. This implies that Gdf1 potentiates Nodal activity by stabilizing a low molecular weight fraction that is susceptible to neutralization by soluble Acvr2 (zeige ACVR2A Antikörper).

  4. Data indicate that the expression of growth/differentiation factor 1 (GDF1) is up-regulated in human dilated cardiomyopathy (DCM)hearts and murine hypertrophic hearts.

  5. Recombinant mouse GDF1 signaling in zebrafish depends on EGF (zeige EGF Antikörper)-CFC (zeige TBCC Antikörper) proteins, but not on Nodal signals. GDF1 binds to and signal through Activin (zeige Actbeta Antikörper) receptors only in the presence of EGF (zeige EGF Antikörper)-CFC (zeige TBCC Antikörper) proteins.

  6. GDF-1 and Nodal converge on ALK4 in the anterior primitive streak to control the formation of organizing centers that are necessary for normal forebrain and branchial arch development

  7. Results suggest that GDF1 and GDF3 (zeige GDF3 Antikörper) together represent the functional mammalian homologs of Vg1.

  8. GDF1 regulates the activity and signaling range of Nodal through direct interaction

GDF1 Antigen-Profil

Protein Überblick

This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a bicistronic mRNA that also encodes the longevity assurance gene.

Genbezeichner und Symbole assoziert mit GDF1

  • growth differentiation factor 1 (GDF1) Antikörper
  • growth differentiation factor 1 (Gdf1) Antikörper
  • AI385651 Antikörper
  • DORV Antikörper
  • DTGA3 Antikörper
  • Gdf-1 Antikörper

Bezeichner auf Proteinebene für GDF1

GDF-1 , embryonic growth/differentiation factor 1

GENE ID SPEZIES
2657 Homo sapiens
14559 Mus musculus
306351 Rattus norvegicus
100686938 Canis lupus familiaris
508576 Bos taurus
100714093 Cavia porcellus
101107353 Ovis aries
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