Granzyme K (Granzyme 3, Tryptase II) Proteine (GZMK)

GZMK product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Zusätzlich bieten wir Ihnen Granzyme K (Granzyme 3, Tryptase II) Antikörper (68) und Granzyme K (Granzyme 3, Tryptase II) Kits (25) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
GZMK 14945 O35205
GZMK 29165 P49864
GZMK 3003 P49863
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Top Granzyme K (Granzyme 3, Tryptase II) Proteine auf antikoerper-online.de

Showing 9 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
487,62 €
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.465,40 €
Details
HOST_Escherichia coli (E. coli) Maus Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 8 Tage
723,20 €
Details
HOST_Escherichia coli (E. coli) Human Unkonjugiert   10 μg Anmelden zum Anzeigen 15 bis 21 Tage
778,03 €
Details
HOST_Escherichia coli (E. coli) Maus His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
624,76 €
Details
HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
379,93 €
Details

GZMK Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,

Rat (Rattus)

Human , ,
,

Weitere Proteine zu Granzyme K (Granzyme 3, Tryptase II) (GZMK) Interaktionspartnern

Mouse (Murine) Granzyme K (Granzyme 3, Tryptase II) (GZMK) Interaktionspartner

  1. The data suggest that T-killer cells control lymphocytic choriomeningitis virus through non-cytotoxic processes that involve gzmK.

  2. It was suggested that a high predisposition to catalepsy in mice can be defined by the Map3k1 (zeige MAP3K1 Proteine), Il6st (zeige IL6ST Proteine), Gzmk, and Hspb3 (zeige HSPB3 Proteine) genes' coexpression network.

  3. GzmK-induced caspase (zeige CASP3 Proteine)-independent death occurs through Bid (zeige BID Proteine)-dependent mitochondrial damage that is different from GzmA (zeige GZMA Proteine)

  4. grzK plays an important role in CD8 (zeige CD8A Proteine)(+) T-cell cytotoxicity both in the presence and absence of grzA and B.

Human Granzyme K (Granzyme 3, Tryptase II) (GZMK) Interaktionspartner

  1. Extracellular granzyme K mediates endothelial activation through the cleavage of PAR-1 (zeige MARK2 Proteine).

  2. Carbamate pesticides significantly reduced the intracellular levels of perforin (zeige PRF1 Proteine), GrA (zeige NR3C1 Proteine), GrB, Gr3 (zeige PRLHR Proteine)/K, and GRN (zeige GRN Proteine) in NK-92CI cells.

  3. Extracellular GrK (zeige GRK4 Proteine) is an unexpected direct modulator of lipopolysaccharide-TLR4 (zeige TLR4 Proteine) signaling during the antimicrobial innate immune response.

  4. Granzyme K plays an important physiological role in immunoregulation of adaptive immunity underlying the cytotoxicity of CD56 (zeige NCAM1 Proteine)(bright) natural killer (NK) cells toward activated T cells.

  5. Gr3 (zeige PRLHR Proteine) proenzymes is activated by cathepsin C (zeige CTSC Proteine) which concomitantly decreased the molecular weight to that of active Gr3 (zeige PRLHR Proteine).

  6. The present findings thus introduce the possibility that human beta-tryptase (zeige TPSAB1 Proteine), after mast cell degranulation and exposure to neutral pH in the tissue, may dissociate into active monomers with properties that are distinct from the tetrameric counterpart.

  7. We found human GzmK triggers rapid cell death independently of caspase (zeige CASP3 Proteine) activation. The features of death are characterized by rapid externalization of phosphatidylserine, nuclear morphological changes and single-stranded DNA nicks.

  8. GzmK-induced caspase (zeige CASP3 Proteine)-independent death occurs through Bid (zeige BID Proteine)-dependent mitochondrial damage that is different from GzmA (zeige GZMA Proteine)

  9. Rsults indicate that plasma levels of Granzyme K could serve as a useful diagnostic marker to stage sepsis, permitting better classification, specific treatments of patients, and may play a functional role in the development of sepsis.

  10. GrK (zeige GRK4 Proteine) not only constitutes a redundant functional backup mechanism that assists GrA (zeige NR3C1 Proteine)-induced cell death but that it also displays a unique function by cleaving its own specific substrates.

Rabbit Granzyme K (Granzyme 3, Tryptase II) (GZMK) Interaktionspartner

  1. Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1 (zeige CCL2 Proteine)) and interleukin-8 (IL-8 (zeige IL8 Proteine)) decreased significantly in Dachengqi decoction treatment group.

Granzyme K (Granzyme 3, Tryptase II) (GZMK) Protein Überblick

Protein Überblick

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.

Genbezeichner und Symbole assoziert mit GZMK

  • granzyme K-like (LOC100052126)
  • granzyme K (Gzmk)
  • granzyme K (granzyme 3; tryptase II) (GZMK)
  • granzyme K (granzyme 3; tryptase II) (Gzmk)
  • granzyme K-like (LOC100345938)
  • TRYP2 Protein

Bezeichner auf Proteinebene für GZMK

NK-Tryp-2 , NK-tryptase-2 , RNK-Tryp-2 , fragmentin-3 , granzyme 3 , granzyme K , granzyme K (serine protease, granzyme 3; tryptase II) , granzyme-3 , tryptase II

GENE ID SPEZIES
100052126 Equus caballus
14945 Mus musculus
29165 Rattus norvegicus
3003 Homo sapiens
100233185 Sus scrofa
426168 Gallus gallus
100727863 Cavia porcellus
100345938 Oryctolagus cuniculus
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