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GZMK product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Zusätzlich bieten wir Ihnen Granzyme K (Granzyme 3, Tryptase II) Antikörper (68) und Granzyme K (Granzyme 3, Tryptase II) Kits (27) und viele weitere Produktgruppen zu diesem Protein an.
Showing 9 out of 11 products:
The data suggest that T-killer cells control lymphocytic choriomeningitis virus through non-cytotoxic processes that involve gzmK.
It was suggested that a high predisposition to catalepsy in mice can be defined by the Map3k1 (zeige MAP3K1 Proteine), Il6st, Gzmk, and Hspb3 (zeige HSPB3 Proteine) genes' coexpression network.
GzmK-induced caspase (zeige CASP3 Proteine)-independent death occurs through Bid (zeige BID Proteine)-dependent mitochondrial damage that is different from GzmA (zeige GZMA Proteine)
grzK plays an important role in CD8 (zeige CD8A Proteine)(+) T-cell cytotoxicity both in the presence and absence of grzA and B.
Extracellular granzyme K mediates endothelial activation through the cleavage of PAR-1 (zeige MARK2 Proteine).
Carbamate pesticides significantly reduced the intracellular levels of perforin (zeige PRF1 Proteine), GrA (zeige NR3C1 Proteine), GrB, Gr3 (zeige PRLHR Proteine)/K, and GRN (zeige GRN Proteine) in NK-92CI cells.
Extracellular GrK (zeige GRK4 Proteine) is an unexpected direct modulator of lipopolysaccharide-TLR4 (zeige TLR4 Proteine) signaling during the antimicrobial innate immune response.
Granzyme K plays an important physiological role in immunoregulation of adaptive immunity underlying the cytotoxicity of CD56 (zeige NCAM1 Proteine)(bright) natural killer (NK) cells toward activated T cells.
Gr3 (zeige PRLHR Proteine) proenzymes is activated by cathepsin C (zeige CTSC Proteine) which concomitantly decreased the molecular weight to that of active Gr3 (zeige PRLHR Proteine).
The present findings thus introduce the possibility that human beta-tryptase (zeige TPSAB1 Proteine), after mast cell degranulation and exposure to neutral pH in the tissue, may dissociate into active monomers with properties that are distinct from the tetrameric counterpart.
We found human GzmK triggers rapid cell death independently of caspase (zeige CASP3 Proteine) activation. The features of death are characterized by rapid externalization of phosphatidylserine, nuclear morphological changes and single-stranded DNA nicks.
Rsults indicate that plasma levels of Granzyme K could serve as a useful diagnostic marker to stage sepsis, permitting better classification, specific treatments of patients, and may play a functional role in the development of sepsis.
GrK (zeige GRK4 Proteine) not only constitutes a redundant functional backup mechanism that assists GrA (zeige NR3C1 Proteine)-induced cell death but that it also displays a unique function by cleaving its own specific substrates.
Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1 (zeige CCL2 Proteine)) and interleukin-8 (IL-8 (zeige IL8 Proteine)) decreased significantly in Dachengqi decoction treatment group.
This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.
, granzyme 3
, granzyme K
, granzyme K (serine protease, granzyme 3; tryptase II)
, tryptase II