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anti-Germ Cell Associated 2 (Haspin) (GSG2) Antikörper

Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. Zusätzlich bieten wir Ihnen Germ Cell Associated 2 (Haspin) Proteine (5) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GSG2 83903 Q8TF76
GSG2 687827  
GSG2 14841 Q9Z0R0
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Top anti-Germ Cell Associated 2 (Haspin) Antikörper auf antikoerper-online.de

Showing 10 out of 49 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB Haspin Antibody (R330) (ABIN1882168) western blot analysis in Daudi,Raji cell line lysates (35 µg/lane). This demonstrates the Haspin antibody detected the Haspin protein (arrow). Haspin Antibody (R330) (ABIN1882168) western blot analysis in Daudi,Raji cell line lysates (35 µg/lane). This demonstrates the Haspin antibody detected the Haspin protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-GSG2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate WB Suggested Anti-GSG2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control:.21_B cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert IHC (p), IP, IHC, WB 0.1 mL Anmelden zum Anzeigen 3 bis 5 Tage
455,00 €
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Maus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen APC IHC, ELISA   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.150,64 €
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Human Kaninchen Unkonjugiert ELISA   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
845,08 €
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Human Kaninchen Alexa Fluor 555 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 17 Tage
366,11 €
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Human Kaninchen Alexa Fluor 488 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 17 Tage
366,11 €
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GSG2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Germ Cell Associated 2 (Haspin) Antikörper

  1. Human Polyclonal GSG2 Primary Antibody für IHC (p), WB - ABIN1882168 : Dai, Sultan, Taylor, Higgins: The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment. in Genes & development 2005 (PubMed)
    Zeige alle 3 Referenzen für ABIN1882168

Weitere Antikörper gegen Germ Cell Associated 2 (Haspin) Interaktionspartner

Fruit Fly (Drosophila melanogaster) Germ Cell Associated 2 (Haspin) (GSG2) Interaktionspartner

Human Germ Cell Associated 2 (Haspin) (GSG2) Interaktionspartner

  1. Haspin kinase plays a key role in maintaining the slowly exchanging centromere Borealin (zeige CDCA8 Antikörper) pool.

  2. Haspin activity affects the phosphorylation state of proteins involved in gene expression regulation and splicing.

  3. Haspin inhibitors reveal centromeric roles of Aurora B (zeige AURKB Antikörper) in chromosome movement and spindle checkpoint signaling

  4. Aurora B (zeige AURKB Antikörper) phosphorylates Haspin to promote generation of H3T3ph and that Aurora B kinase (zeige AURKB Antikörper) activity is required for normal chromosomal localization of the CPC, indicating an intimate linkage between Aurora B (zeige AURKB Antikörper) and Haspin functions in mitosis

  5. findings show phosphorylation of histone H3-threonine 3 mediated by Haspin cooperates with Bub1-mediated histone 2A-serine 121 phosphorylation in targeting the chromosomal passenger complex to the inner centromere in fission yeast and human cells

  6. phosphorylation of H3T3 by Haspin is necessary for chromosomal passenger complex(CPC) accumulation at centromeres; Survivin (zeige BIRC5 Antikörper) binds to H3T3ph; H3T3ph generated by Haspin positions CPC at centromeres to regulate selected targets of Aurora B (zeige AURKB Antikörper) during mitosis

  7. Haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesion.

  8. Haspin is a relatively newly discovered kinase that phosphorylates histone H3 (zeige HIST3H3 Antikörper) during mitosis and appears to play a role in regulating chromosome behavior during cell division. [REVIEW]

  9. This work reveals a new kinase involved in composing the histone code and adds haspin to the select group of kinases that integrate regulation of chromosome and spindle function during mitosis and meiosis

  10. Haspin is required to maintain centromeric cohesion during mitosis.

Mouse (Murine) Germ Cell Associated 2 (Haspin) (GSG2) Interaktionspartner

  1. Data implicate haspin as a regulator of the chromosomal passenger complex and chromosome segregation during meiosis I.

  2. the tissue-dependent and differentially methylated region functions as a modulator in a DNA methylation (zeige HELLS Antikörper)-dependent manner; Gsg2 is under epigenetic control

  3. the 193-bp DNA sequence in Haspin promotor is sufficient for the specific, bidirectional, and synchronous expression in germ cells in the testis.

Germ Cell Associated 2 (Haspin) (GSG2) Antigen-Profil

Protein Überblick

Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle (By similarity).

Genbezeichner und Symbole assoziert mit GSG2

  • serine/threonine-protein kinase haspin-like protein (Haspin) Antikörper
  • germ cell associated 2 (haspin) (GSG2) Antikörper
  • CG40080 gene product from transcript CG40080-RA (Haspin) Antikörper
  • putative serine/threonine-protein kinase haspin homolog (Haspin) Antikörper
  • germ cell associated 2 (haspin) (Gsg2) Antikörper
  • germ cell-specific gene 2 (Gsg2) Antikörper
  • BcDNA:LD07633 Antikörper
  • CG40080 Antikörper
  • Dmel\\CG40080 Antikörper
  • Haspin Antikörper
  • NV16901 Antikörper

Bezeichner auf Proteinebene für GSG2

serine/threonine-protein kinase haspin-like protein , germ cell associated 2 (haspin) , haspin , CG40080-PA , Haspin-PA , putative serine/threonine-protein kinase haspin homolog , H-haspin , germ cell-specific gene 2 protein , haploid germ cell-specific nuclear protein kinase , serine/threonine-protein kinase haspin

GENE ID SPEZIES
552287 Apis mellifera
748101 Pan troglodytes
3355064 Drosophila melanogaster
100122327 Nasonia vitripennis
83903 Homo sapiens
767819 Bos taurus
687827 Rattus norvegicus
14841 Mus musculus
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