Geranylgeranyl Diphosphate Synthase 1 Proteine (GGPS1)

GGPS1 is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. Zusätzlich bieten wir Ihnen GGPS1 Antikörper (126) und GGPS1 Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
GGPS1 9453 O95749
GGPS1 14593 Q9WTN0
Ratte GGPS1 GGPS1 291211 Q6F596
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Top GGPS1 Proteine auf antikoerper-online.de

Showing 10 out of 22 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
303,81 €
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HOST_Human Cells Human His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
312,50 €
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HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 8 bis 11 Tage
438,90 €
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HOST_Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 8 bis 9 Tage
523,81 €
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HOST_Escherichia coli (E. coli) Human His tag   10 μg Anmelden zum Anzeigen 13 bis 15 Tage
285,71 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.662,70 €
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GGPS1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , , ,
Mouse (Murine)
,

Am meisten referenzierte GGPS1 Proteine

  1. Human GGPS1 Protein expressed in Escherichia coli (E. coli) - ABIN667204 : Okada, Saito, Nakagawa, Kawamukai, Kamiya: Five geranylgeranyl diphosphate synthases expressed in different organs are localized into three subcellular compartments in Arabidopsis. in Plant physiology 2000 (PubMed)

Weitere Proteine zu Geranylgeranyl Diphosphate Synthase 1 (GGPS1) Interaktionspartnern

Arabidopsis thaliana Geranylgeranyl Diphosphate Synthase 1 (GGPS1) Interaktionspartner

  1. GGPS1 is a key gene in the chlorophyll biosynthetic pathway.

Human Geranylgeranyl Diphosphate Synthase 1 (GGPS1) Interaktionspartner

  1. results may support a model in which accumulation of susceptibility variants (including some in relevant genes, notably GGPS1) may lead to a possible genetic component of predisposition to atypical femoral fractures.

  2. GGPPS1 may play a critical role during the development of HCC (zeige FAM126A Proteine) from cirrhosis and is of clinical significance for predicting biological character of HCC (zeige FAM126A Proteine).

  3. Egr-1 (zeige EGR1 Proteine) most likely does not induce the constitutive activation of Erk1/2 through its target gene GGPS1.

  4. the Egr-1 (zeige EGR1 Proteine)/GGPPS/Erk1/2 pathway is responsible for insulin (zeige INS Proteine) resistance during hyperinsulinism

  5. these results reveal a new EGR-1 (zeige EGR1 Proteine)/GGPPS/MAPK (zeige MAPK1 Proteine) signaling pathway that controls cigarette smoke-induced pulmonary inflammation.

  6. Study suggested that GGPS1 -8188A ins (zeige INS Proteine)/del polymorphism may confer susceptibility to femoral neck BMD (zeige BEST1 Proteine) response to bisphosphonate therapy in Korean women.

  7. Farnesyltranstransferase mutations are associated with lonafarnib resistance

  8. Evidence for a non-membrane bound isoform of geranylgeranyl diphosphate synthase 1 in rat.

Mouse (Murine) Geranylgeranyl Diphosphate Synthase 1 (GGPS1) Interaktionspartner

  1. Depletion of GGPP in mouse oocytes impaired the proliferation of granulosa cells, primary-secondary follicle transition and female fertility. GGPP depletion inhibited Rho GTPase (zeige RACGAP1 Proteine) geranylgeranylation and its GTPase (zeige RACGAP1 Proteine) activity.

  2. our data suggest that GGPPS is essential for maintaining fetal lung branching morphogenesis, which is possibly through regulating K-Ras prenylation.

  3. GGPPS-controlled protein geranylgeranylation, which regulates formation of the insulin (zeige INS Proteine) granule docked pool, is critical for beta cell function and insulin (zeige INS Proteine) release during the development of type 2 diabetes mellitus

  4. findings imply that GGPPS deletion induces hepatocyte apoptosis, which makes the liver vulnerable to hepatotoxicity.

  5. the impact of deleting one copy of FT or GGT (zeige GGT1 Proteine) on the development of amyloid-beta (Abeta (zeige APP Proteine))-associated neuropathology and learning/memory impairments in APPPS1 double transgenic mice.

  6. The authors show that an early response transcription factor Egr-1 (zeige EGR1 Proteine) could tilt the signalling balance by blocking PI3K/Akt (zeige AKT1 Proteine) signalling through PTEN and augmenting Erk/MAPK (zeige MAPK1 Proteine) signalling through GGPPS, resulting in insulin (zeige INS Proteine) resistance in adipocytes.

  7. the Egr-1 (zeige EGR1 Proteine)/GGPPS/Erk1/2 pathway is responsible for insulin (zeige INS Proteine) resistance during hyperinsulinism

  8. these results reveal a new EGR-1 (zeige EGR1 Proteine)/GGPPS/MAPK (zeige MAPK1 Proteine) signaling pathway that controls cigarette smoke-induced pulmonary inflammation.

  9. GGPP is critical for the cell-to-cell contact-induced differentiation, in which the down-regulation of GGPPS might be involved.

GGPS1 Protein Überblick

Protein Überblick

This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene.

Genbezeichner und Symbole assoziert mit GGPS1

  • geranylgeranyl pyrophosphate synthase 1 (GGPS1)
  • geranylgeranyl pyrophosphate synthetase (GGPS1)
  • geranyl pyrophosphate synthase (GGPS1)
  • geranylgeranyl pyrophosphate synthase,chloroplastic (gGPS1)
  • geranylgeranyl diphosphate synthase 1 (GGPS1)
  • geranylgeranyl diphosphate synthase 1 (ggps1)
  • geranylgeranyl diphosphate synthase 1 (LOC100340259)
  • geranylgeranyl diphosphate synthase 1 (Ggps1)
  • 1810026C22Rik Protein
  • 9530089B04Rik Protein
  • AI843169 Protein
  • C79210 Protein
  • Crlf3 Protein
  • DDBDRAFT_0192027 Protein
  • DDBDRAFT_0233098 Protein
  • DDB_0192027 Protein
  • DDB_0233098 Protein
  • fb05f09 Protein
  • geranylgeranyl pyrophosphate synthase 1 Protein
  • GGPPS Protein
  • GGPPS1 Protein
  • qm Protein
  • rGGPS1a Protein
  • rGGPS1a1 Protein
  • rGGPS1a2 Protein
  • rGGPS1a3 Protein
  • wu:fb05f09 Protein
  • zgc:56514 Protein
  • zgc:101591 Protein

Bezeichner auf Proteinebene für GGPS1

geranylgeranyl pyrophosphate synthase 1 , geranylgeranyl pyrophosphate synthetase , geranyl pyrophosphate synthase , geranylgeranyl pyrophosphate synthase,chloroplastic , geranylgeranyl diphosphate synthase 1 , (2E,6E)-farnesyl diphosphate synthase , GGPP synthase , GGPPSase , dimethylallyltranstransferase , farnesyl diphosphate synthase , farnesyltranstransferase , geranylgeranyl pyrophosphate synthase , geranyltranstransferase , GGPP synthetase

GENE ID SPEZIES
778310 Solanum lycopersicum
829834 Arabidopsis thaliana
7448761 Thalassiosira pseudonana CCMP1335
8245279 Micromonas sp. RCC299
9680683 Micromonas pusilla CCMP1545
10865825 Parachlamydia acanthamoebae UV-7
427092 Gallus gallus
549876 Xenopus (Silurana) tropicalis
8629314 Dictyostelium discoideum AX4
100340259 Oryctolagus cuniculus
9453 Homo sapiens
479198 Canis lupus familiaris
780882 Bos taurus
14593 Mus musculus
291211 Rattus norvegicus
336798 Danio rerio
100049104 Xenopus laevis
Ausgewählte Anbieter für GGPS1 Proteine (GGPS1)
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