General Transcription Factor IIA, 1, 19/37kDa Proteine (GTF2A1)

Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A\; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). Zusätzlich bieten wir Ihnen GTF2A1 Antikörper (59) und GTF2A1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
GTF2A1 83602 Q99PM3
GTF2A1 83830 O08949
GTF2A1 2957 P52655
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Showing 9 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Pongo abelii His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.886,19 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.887,93 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
484,01 €
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HOST_Escherichia coli (E. coli) Chemical Unkonjugiert   10 μg Anmelden zum Anzeigen 1 bis 3 Tage
469,44 €
Details

GTF2A1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,

Rat (Rattus)

Human , ,
,

Weitere Proteine zu General Transcription Factor IIA, 1, 19/37kDa (GTF2A1) Interaktionspartnern

Mouse (Murine) General Transcription Factor IIA, 1, 19/37kDa (GTF2A1) Interaktionspartner

  1. TFIIA is the principal TASP1 (zeige TASP1 Proteine) substrate that orchestrates craniofacial morphogenesis.

Human General Transcription Factor IIA, 1, 19/37kDa (GTF2A1) Interaktionspartner

  1. Data suggest that many TATA-box-containing promoters contain a TFIIA recognition element (IIARE) that activates transcription by increasing the recruitment of RNA polymerase II, TFIIA (TF2A1/TF2A2 (zeige GTF2A2 Proteine) subunits), TAF4 (zeige TAF4 Proteine), and P300 (zeige EP300 Proteine). (TAF4 (zeige TAF4 Proteine) = TATA box binding protein (TBP (zeige TBP Proteine))-associated factor (zeige TAF5 Proteine), RNA polymerase II, C1; P300 (zeige EP300 Proteine) = E1A binding protein p300 (zeige EP300 Proteine))

  2. The interaction of TBP (zeige TBP Proteine)-like protein with TFIIA is essential to suppress proteasome-dependent turnover of TBP (zeige TBP Proteine)-like protein

  3. Our results provide first evidence that Taspase1 processing affects TFIIA regulation of TFIID (zeige TBP Proteine) and suggest that Taspase1 processing of TFIIA is required to establish INR (zeige INSR Proteine)-selective core promoter activity in the presence of NC2 (zeige GTF2H5 Proteine).

  4. spatial positioning of the DNA-bound activation domain is important for efficient activation, possibly by maximizing its interactions with the transcriptional machinery including the TBP (zeige TBP Proteine)-TFIIA-TFIIB (zeige GTF2B Proteine)-promoter quaternary complex

  5. Results present the X-ray structures of human and yeast TATA box-binding protein /transcription factor IIA/DNA complexes at 2.1A and 1.9A resolution, respectively

  6. transcription factor IIA may regulate the intracellular molecular state and the function of TATA-binding protein-like protein (TLP) through its property of binding to TLP

  7. Transfected taspase 1 (zeige TASP1 Proteine) enhances cleavage of TFIIA, and RNA interference knockdown of endogenous taspase 1 (zeige TASP1 Proteine) diminishes cleavage of TFIIA in vivo.

  8. TFIIA induces a conformational change within the TBP (zeige TBP Proteine)/TATA complex that enhances its stability under both in vitro and physiological salt conditions.

  9. GTF2A1 alone, or GTF2A1 plus HAAO (zeige HAAO Proteine) are excellent candidate biomarkers for detecting Ovarian cancer

  10. V96F substitution of a deamidated human GTF2A1 (TFIIA) peptide promotes T-cell activation in an in vitro model of Celiac disease inflammation.

GTF2A1 Protein Überblick

Protein Überblick

Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A\; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993

Genbezeichner und Symbole assoziert mit GTF2A1

  • general transcription factor IIA, 1, 19/37kDa (GTF2A1)
  • general transcription factor IIA, 1, 19/37kDa (gtf2a1-b)
  • general transcription factor IIA, 1 (gtf2a1)
  • general transcription factor IIA, 1, 19/37kDa (gtf2a1)
  • general transcription factor IIA, 1, 19/37kDa (gtf2a1-a)
  • general transcription factor II A, 1 (Gtf2a1)
  • general transcription factor IIA, 1 (Gtf2a1)
  • 6330549H03Rik Protein
  • AA536742 Protein
  • AA959775 Protein
  • AW060250 Protein
  • fc15h02 Protein
  • fj36b10 Protein
  • GTF2A1 Protein
  • Tf2a Protein
  • TF2A1 Protein
  • TFIIA Protein
  • TFIIA-42 Protein
  • Tfiia1 Protein
  • TfIIAa/b Protein
  • tfiiaa/b-1 Protein
  • tfiiaa/b-2 Protein
  • TFIIAL Protein
  • wu:fc15h02 Protein
  • wu:fj36b10 Protein
  • zgc:55847 Protein

Bezeichner auf Proteinebene für GTF2A1

general transcription facter IIA subunit 1 variant 1 , transcription initiation factor IIA subunit 1 , transcription factor IIA large subunit-2 , general transcription factor IIA, 1, 19/37kDa , TFIIA alpha, p55 , transcription factor IIA large subunit-1 , TFIIA alpha/beta , general transcription factor IIA subunit 1 , general transcription factor IIa, 1 (37kD and 19kD subunits) , TFIIA large subunit , general transcription factor 2a, 1 , glucose regulated protein, 58kD pseudogene , transcription initiation factor TFIIA 42 kDa subunit

GENE ID SPEZIES
423389 Gallus gallus
399209 Xenopus laevis
323974 Danio rerio
467523 Pan troglodytes
549662 Xenopus (Silurana) tropicalis
613006 Canis lupus familiaris
708130 Macaca mulatta
785612 Bos taurus
398704 Xenopus laevis
100059967 Equus caballus
100568291 Ovis aries
100580580 Nomascus leucogenys
83602 Mus musculus
83830 Rattus norvegicus
2957 Homo sapiens
100172100 Pongo abelii
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