anti-Four and A Half LIM Domains 1 (FHL1) Antikörper

FHL1 encodes a member of the four-and-a-half-LIM-only protein family. Zusätzlich bieten wir Ihnen Four and A Half LIM Domains 1 Kits (11) und Four and A Half LIM Domains 1 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FHL1 2273 Q13642
FHL1 14199 P97447
FHL1 25177 Q9WUH4
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Top anti-Four and A Half LIM Domains 1 Antikörper auf antikoerper-online.de

Showing 10 out of 107 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IC, IF, WB 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Mouse Target Name: FHL1 Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml Host: Rabbit Target Name: FHL1 Sample Type: Human Fetal Brain Antibody Dilution: 1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-FHL1 <br /> Antibody Titration: 0.1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Human Muscle 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of FHL1 Antibody (C-term) (ABIN390835) in NIH-3T3 cell line lysates (35 µg/lane). FHL1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human skeletal muscle reacted with FHL1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN185289 staining (0.05µg/ml) of Human Muscle lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Ziege Unkonjugiert ELISA, WB ABIN185290 (0.01µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Ziege Unkonjugiert ELISA, WB ABIN250290 (0.01ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Hamster Ziege Unkonjugiert IHC (p), ELISA, WB Human Testis (formalin-fixed, paraffin-embedded) stained with FHL1 antibody ABIN337221 at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p), WB Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with FHL1 antibody ABIN462171 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Testis (formalin-fixed, paraffin-embedded) stained with FHL1 antibody ABIN462171 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$676.50
Details

FHL1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Four and A Half LIM Domains 1 Antikörper

  1. Cow (Bovine) Polyclonal FHL1 Primary Antibody für IHC, WB - ABIN2775759 : McGrath, Mitchell, Coghill, Robinson, Brown: Skeletal muscle LIM protein 1 (SLIM1/FHL1) induces alpha 5 beta 1-integrin-dependent myocyte elongation. in American journal of physiology. Cell physiology 2003 (PubMed)
    Show all 12 Pubmed References

  2. Human Polyclonal FHL1 Primary Antibody für IHC, ELISA - ABIN185289 : Brown, McGrath, Ooms, Gurung, Maimone, Mitchell et al.: Characterization of two isoforms of the skeletal muscle LIM protein 1, SLIM1. Localization of SLIM1 at focal adhesions and the isoform slimmer in the nucleus of myoblasts and cytoplasm of myotubes ... in The Journal of biological chemistry 1999 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal FHL1 Primary Antibody für ELISA, WB - ABIN250290 : Zhang, Chen, Sharma, Moon, Sheftel, Dawood, Nghiem, Wu, Li, Gramolini, Sorensen, Penninger, Brumell, Liu: HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress. in Nature communications 2014 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal FHL1 Primary Antibody für IHC (p), IHC - ABIN250288 : Gramolini, Kislinger, Alikhani-Koopaei, Fong, Thompson, Isserlin, Sharma, Oudit, Trivieri, Fagan, Kannan, Higgins, Huedig, Hess, Arab, Seidman, Seidman, Frey, Perry, Backx, Liu, MacLennan, Emili: Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses. in Molecular & cellular proteomics : MCP 2008 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal FHL1 Primary Antibody für ICC, IF - ABIN4311629 : Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies. in Molecular & cellular proteomics : MCP 2006 (PubMed)

  6. Human Monoclonal FHL1 Primary Antibody für ELISA, WB - ABIN560899 : Chen, Ferrington, Thompson: Carbonic anhydrase III and four-and-a-half LIM protein 1 are preferentially oxidized with muscle unloading. in Journal of applied physiology (Bethesda, Md. : 1985) 2008 (PubMed)

  7. Human Monoclonal FHL1 Primary Antibody für ELISA, WB - ABIN515655 : Sakashita, Mimori, Tanaka, Kamohara, Inoue, Sawada, Hirakawa, Mori: Clinical significance of loss of Fhl1 expression in human gastric cancer. in Annals of surgical oncology 2008 (PubMed)

  8. Cow (Bovine) Polyclonal FHL1 Primary Antibody für IHC (p), ELISA - ABIN2473617 : Emmanuele, Kubota, Garcia-Diaz, Garone, Akman, Sánchez-Gutiérrez, Escudero, Kariya, Homma, Tanji, Quinzii, Hirano: Fhl1 W122S causes loss of protein function and late-onset mild myopathy. in Human molecular genetics 2015 (PubMed)

Weitere Antikörper gegen Four and A Half LIM Domains 1 Interaktionspartner

Human Four and A Half LIM Domains 1 (FHL1) Interaktionspartner

  1. Low FHL1 expression is associated with head and neck squamous cell carcinoma.

  2. We have uncovered FHL1 as a novel potential regulator of calcium homeostasis in both fish and humans and have implicated it in isolated hypoparathyroidism.

  3. Mutations in FHL1 cause unclassifiable cardiomyopathy with coexisting Emery-Dreifuss muscular dystrophy.

  4. results provide evidence that FHL1A interacts with PLEKHG2 (zeige PLEKHG2 Antikörper) and regulates cell morphological change through the activity of PLEKHG2 (zeige PLEKHG2 Antikörper).

  5. a novel FHL1 splice site variant results in the absence of FHL1A and the abundance of FHL1C, which may contribute to the complex and severe phenotype of Uruguay syndrome.

  6. Knockdown of FHL1 with FHL1 small interfering RNA (siRNA) promoted tumor growth and Cyclin D and cyclin E (zeige CCNE1 Antikörper) were markedly elevated at both the protein and mRNA level.

  7. results indicate that anti-FHL1 autoantibodies in peripheral blood have promising potential as a biomarker to identify a subset of severe IIM.

  8. In healthy individuals, FHL1A is the predominant splice variant and is mainly found in skeletal and cardiac muscle. In two individuals with an Emery-Dreifuss plus phenotype with pulmonary artery hypoplasia and facial dysmorphology, there was demonstrated loss of isoform A and B, and an almost 200-fold overexpression of isoform C.

  9. FRG1 (zeige FRG1 Antikörper) mice overexpressing FHL1 showed an improvement in the dystrophic phenotype

  10. FHL1 shRNA could significantly accelerate tumor cell growth via inhibiting the expression of FHL1

Mouse (Murine) Four and A Half LIM Domains 1 (FHL1) Interaktionspartner

  1. KyoT2 downregulates airway remodeling and resistance in asthmatic mice through a Hes1-dependent mechanism.

  2. Results found that osteogenesis increases with the overexpression of Fhl1 and decreases with reduced Fhl1 expression and suggest that Fhl1 mediates interacting estrogen and Wnt (zeige WNT2 Antikörper) signaling during osteogenesis.

  3. Findings indicate that loss of function is responsible for the myopathy in the Fhl1 W122S knock-in mice.

  4. The CSL (zeige SMPX Antikörper)-KyoT2 corepressor complex is a negative regulator of Notch (zeige NOTCH1 Antikörper) signaling.

  5. Data show that loss of FHL1 function leads to myopathy in vivo and suggest that loss of function of FHL1 may be one of the mechanisms underlying muscle dystrophy in patients with FHL1 mutations.

  6. Fhl1 transcriptional changes provide salutary effects on stressed myocytes in cardiomyopathy.

  7. Data suggest Fhl1 (four-and-a-half LIM domains protein 1) and FHL2 (four-and-a-half LIM domains protein 2 (zeige FHL2 Antikörper)) bind to and regulate activity of Prkd1 (protein kinase D (zeige PRKD1 Antikörper) 1) in cardiac/ventricular myocytes; knockdown of Fhl1 down-regulates Prkd1 (zeige PRKD1 Antikörper) activation.

  8. A novel mechanism involving four-and-a-half LIM domain protein (zeige PDLIM7 Antikörper)-1 and extracellular signal-regulated kinase-2 (zeige MAPK1 Antikörper) regulates titin (zeige TTN Antikörper) phosphorylation and mechanics.

  9. Wnt (zeige WNT2 Antikörper) signaling induces muscle cell differentiation, at least partly, through Fhl1 activation.

  10. FHL1 is a novel regulator of myosin-binding (zeige PPP1R12A Antikörper) protein C (zeige PROC Antikörper) activity that may have a role in sarcomere assembly

Pig (Porcine) Four and A Half LIM Domains 1 (FHL1) Interaktionspartner

  1. The LIM domain protein (zeige PDLIM7 Antikörper) FHL1C interacts with tight junction protein ZO-1 (zeige TJP1 Antikörper) contributing to the epithelial-mesenchymal transition of a breast adenocarcinoma cell line.

Four and A Half LIM Domains 1 (FHL1) Antigen-Profil

Protein Überblick

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.

Genbezeichner und Symbole assoziert mit FHL1

  • four and a half LIM domains 1 (fhl1) Antikörper
  • four and a half LIM domains 1 (FHL1) Antikörper
  • four and a half LIM domains 1a (fhl1a) Antikörper
  • Four and a half LIM domains protein 1 (fhl1) Antikörper
  • four and a half LIM domains 1 S homeolog (fhl1.S) Antikörper
  • four and a half LIM domains 1 (Fhl1) Antikörper
  • DKFZp468O1927 Antikörper
  • fhl Antikörper
  • FHL-1 Antikörper
  • Fhl1 Antikörper
  • FHL1A Antikörper
  • FHL1B Antikörper
  • fhla Antikörper
  • FLH1A Antikörper
  • KyoT Antikörper
  • MGC89165 Antikörper
  • SLIM Antikörper
  • SLIM-1 Antikörper
  • SLIM1 Antikörper
  • SLIMMER Antikörper
  • XMPMA Antikörper
  • zgc:92025 Antikörper

Bezeichner auf Proteinebene für FHL1

four and a half LIM domains 1 , four and a half LIM domains protein 1-like , four and a half LIM domains a , four and a half LIM domains protein 1 , Four and a half LIM domains protein 1 , four and a half lim domains protein 1 , LIM protein SLIMMER , four-and-a-half Lin11, Isl-1 and Mec-3 domains 1 , skeletal muscle LIM-protein 1 , FHL-1 , RAM14-1 , RBP-associated molecule 14-1 , SLIM , SLIM-1 , four and a half LIM domains 1 protein

GENE ID SPEZIES
448334 Xenopus (Silurana) tropicalis
710692 Macaca mulatta
100172515 Pongo abelii
100307044 Ovis aries
100357263 Oryctolagus cuniculus
100387250 Callithrix jacchus
100590327 Nomascus leucogenys
399646 Danio rerio
100196873 Salmo salar
100529032 Ictalurus punctatus
447182 Xenopus laevis
2273 Homo sapiens
14199 Mus musculus
25177 Rattus norvegicus
509056 Bos taurus
397667 Sus scrofa
492162 Canis lupus familiaris
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