anti-Fibroblast Growth Factor 14 (FGF14) Antikörper

The protein encoded by FGF14 is a member of the fibroblast growth factor (FGF) family. Zusätzlich bieten wir Ihnen FGF14 Proteine (13) und FGF14 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FGF14 2259 Q92915
FGF14 14169 P70379
FGF14 63851 Q8R5L7
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Top anti-FGF14 Antikörper auf antikoerper-online.de

Showing 10 out of 47 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-FGF14 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Lung 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
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Human Kaninchen Unkonjugiert IC, IF, WB Immunofluorescent analysis of FGF14 staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Western blot analysis of FGF14 expression in U937 (A), mouse brain (B), mouse spleen (C), rat brain (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
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Huhn Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
722,86 €
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Human Kaninchen Cy5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen HRP IHC (p), WB   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy7 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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FGF14 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-FGF14 Antikörper

  1. Mammalian Monoclonal FGF14 Primary Antibody für ISt, IHC - ABIN1304635 : Yan, Pablo, Wang, Pitt: FGF14 modulates resurgent sodium current in mouse cerebellar Purkinje neurons. in eLife 2014 (PubMed)
    Show all 12 Pubmed References

Weitere Antikörper gegen FGF14 Interaktionspartner

Human Fibroblast Growth Factor 14 (FGF14) Interaktionspartner

  1. Either the FGF14(V160A) or the FGF14(K74A/I76A) mutation was sufficient to abolish the FGF14-dependent regulation of peak transient Na(+) currents and the voltage-dependent activation and steady-state inactivation of Nav1.6 (zeige SCN8A Antikörper); but only V160A with a concomitant alanine mutation at Tyr (zeige TYR Antikörper)-158 could impede FGF14-dependent modulation of the channel fast inactivation.

  2. study reports on a two-generation French Canadian family affected with autosomal dominant episodic ataxia caused by a frameshift mutation leading to a premature stop codon in FGF14

  3. identified the PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) pathway, the cell-cycle regulator (zeige CDKN2A Antikörper) Wee1 kinase (zeige WEE1 Antikörper), and protein kinase C (PKC (zeige PKC Antikörper)) as prospective regulatory nodes of neuronal excitability through modulation of the FGF14:Nav1.6 (zeige SCN8A Antikörper) complex.

  4. family demonstrates phenotypic variability of FGF14 deletions (SCA 27), fever sensitivity of ataxia and the added value of SNP-array analysis in making a diagnosis

  5. inhibition of GSK3 (zeige GSK3b Antikörper) reduces the assembly of the FGF14.Nav channel complex, modifies FGF14-dependent regulation of Na(+) currents, and induces dissociation and subcellular redistribution of the native FGF14.Nav channel complex in hippocampal neurons.

  6. THe present study demonstrates that Spinocerebellar ataxia type 27 (SCA27) caused by FGF14 mutation is rare in Chinese SCA patients.

  7. A mutation in the fibroblast growth factor 14 gene is associated with autosomal dominant cerebral ataxia

  8. A G->A variant was found in a single spinocerebellar ataxia patient in the 3' untranslated region, 31 bp to the STOP codon; it did not affect the polyadenylation site. FGF14 mutations are not a major cause of SCA in Caucasians.

  9. Frameshift mutation and polymorphisms in the fibroblast growth factor 14 gene is associated with ataxias

  10. these findings implicate FGF14 as a unique modulator of Nav channel activity in the CNS.

Mouse (Murine) Fibroblast Growth Factor 14 (FGF14) Interaktionspartner

  1. TWEAK (zeige TNFSF12 Antikörper)/Fn14 (zeige TNFRSF12A Antikörper) pathway instrumental in the pathogenesis of spontaneous lupus nephritis

  2. FGF14 is localized in a decreasing proximal to distal gradient along the axon initial segment of Purkinje neurons.

  3. FGF14 regulates presynaptic Ca2 (zeige CA2 Antikörper)+ channels and synaptic transmission in cultured rat neurons.

  4. inhibition of GSK3 (zeige GSK3b Antikörper) reduces the assembly of the FGF14.Nav channel complex, modifies FGF14-dependent regulation of Na(+) currents, and induces dissociation and subcellular redistribution of the native FGF14.Nav channel complex in hippocampal neurons.

  5. Fgf14-deficient mice developed ataxia and a paroxysmal hyperkinetic movement disorder. FGF14 may mediate neuronal signaling, axonal trafficking and synaptosomal function.

  6. FGF14 in regulating synaptic plasticity via presynaptic mechanisms by affecting the mobilization, trafficking, or docking of synaptic vesicles to presynaptic active zones.

  7. these results suggest a role for FGF14 in certain spatial learning functions and synaptic plasticity

  8. Sodium channels in Fhf1 (zeige FGF12 Antikörper)-/-Fhf4-/- granule neurons inactivate at more negative membrane potential, inactivate more rapidly, and are slower to recover from the inactivated state.

  9. results suggest that FGF14 is required for normal Nav1.6 (zeige SCN8A Antikörper) expression in Purkinje neurons, and that the loss of FGF14 impairs spontaneous and repetitive firing in Purkinje neurons by altering the expression of Nav1.6 (zeige SCN8A Antikörper) channels

FGF14 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit FGF14

  • fibroblast growth factor 14 (FGF14) Antikörper
  • fibroblast growth factor 14 (fgf14) Antikörper
  • fibroblast growth factor 14 (LOC100229510) Antikörper
  • fibroblast growth factor 14 (LOC100358876) Antikörper
  • fibroblast growth factor 14 (Fgf14) Antikörper
  • FGF-14 Antikörper
  • FGF14 Antikörper
  • FHF-4 Antikörper
  • Fhf4 Antikörper
  • mFHF-4(1B) Antikörper
  • SCA27 Antikörper

Bezeichner auf Proteinebene für FGF14

fibroblast growth factor homologous factor 4 , fibroblast growth factor 14 , bA397O8.2 , FGF-14 , FGF homologus factor 4b

GENE ID SPEZIES
395554 Gallus gallus
497642 Danio rerio
701077 Macaca mulatta
739338 Pan troglodytes
100217328 Xenopus (Silurana) tropicalis
100229510 Taeniopygia guttata
100358876 Oryctolagus cuniculus
2259 Homo sapiens
14169 Mus musculus
63851 Rattus norvegicus
485537 Canis lupus familiaris
615488 Bos taurus
Ausgewählte Anbieter für anti-FGF14 (FGF14) Antikörper
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