anti-Family with Sequence Similarity 3, Member C (FAM3C) Antikörper

FAM3C is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. Zusätzlich bieten wir Ihnen FAM3C Proteine (17) und FAM3C Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FAM3C 10447 Q92520
FAM3C 27999 Q91VU0
FAM3C 312159 Q810F4
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Top anti-FAM3C Antikörper auf antikoerper-online.de

Showing 10 out of 53 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-FAM3C Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>721_B cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Huhn Kaninchen Unkonjugiert IHC (p), WB Human Skin (formalin-fixed, paraffin-embedded) stained with FAM3C antibody ABIN293839 at 5-10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Paraformaldehyde-fixed, paraffin embedded rat brain, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with FAM3C Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Human Kaninchen Unkonjugiert WB FAM3C antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details
Huhn Kaninchen Unkonjugiert IHC (p), IHC, WB Immunohistochemistry-Paraffin: FAM3C Antibody [NBP1-39744] - Staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 0.05 mg Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details
Human Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 12 bis 14 Tage
$541.80
Details
Huhn Kaninchen Unkonjugiert IHC, WB 0.05 mg Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen FITC IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

FAM3C Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-FAM3C Antikörper

  1. Cow (Bovine) Polyclonal FAM3C Primary Antibody für WB - ABIN2782061 : Dublineau, Grison, Grandcolas, Baudelin, Tessier, Suhard, Frelon, Cossonnet, Claraz, Ritt, Paquet, Voisin, Gourmelon: Absorption, accumulation and biological effects of depleted uranium in Peyer's patches of rats. in Toxicology 2006 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen FAM3C Interaktionspartner

Human Family with Sequence Similarity 3, Member C (FAM3C) Interaktionspartner

  1. Covalent dimerization of ILEI is associated with breast cancer metastasis.

  2. Data suggest that ILEI does not form interleukin-like four helix-bundle structures; ILEI exists as monomers and as covalent dimers; ILEI dimer exhibits a trans-linked domain swap converting an intramolecular disulfide to an intermolecular disulfide; dimeric ILEI appears to be involved in neoplastic invasiveness.

  3. Results demonstrate that phenotype switching regulates ILEI expression, and that ILEI regulates partial phenotype switching in MITF (zeige MITF Antikörper)-low melanoma cell lines.

  4. Ectopic overexpression of UBE4A (zeige UBE4A Antikörper), but not UBE3C (zeige UBE3C Antikörper), in cells was downregulated in vitro migration and invasion in these cells. Cumulatively, our data reveals a novel post-translational regulatory mechanism of regulating ILEI1 expression, a protein required for metastatic progression in prostate cancer cells

  5. Study used immunohistochemical staining and biochemical fractionation to examine the regional distribution and subcellular localization of ILEI in mouse brains and in autopsy brains of patients with Alzheimer's disease; results suggest that a decline of ILEI expression may cause accumulation of Abeta (zeige APP Antikörper) in the brain and the eventual development of Alzheimer's disease.

  6. FAM3C expression was dramatically increased in esophageal squamous cell carcinoma and might serve as a valuable prognostic indicator for esophageal squamous cell carcinoma patients after surgery

  7. Altered subcellular ILEI localization strongly correlates with high tumor cell-associated uPAR (zeige PLAUR Antikörper) protein expression.

  8. Our findings indicate that cytoplasmic ILEI expression is a potential marker of EMT (zeige ITK Antikörper) and tumour progression in colorectal cancer. ILEI is an independent predictive factor associated with poor prognosis in colorectal cancer.

  9. ILEI could induce, as well as maintain, CD24 (zeige CD24 Antikörper)(low)CD44 (zeige CD44 Antikörper)(high) subpopulation in A549 cells treated with TGF-beta (zeige TGFB1 Antikörper), which might explain its capability to induce metastatic progression.

  10. At the FAM3C gene locus where rs7776725 was located, we identified several other SNPs (rs4727922, rs1803389, rs718766 and rs7793554) that were also associated with BMD (zeige BEST1 Antikörper).

Mouse (Murine) Family with Sequence Similarity 3, Member C (FAM3C) Interaktionspartner

  1. Data suggest that Ilei does not form interleukin-like four helix-bundle structures; Ilei exists as monomers and as covalent dimers; Ilei dimer exhibits a trans-linked domain swap converting an intramolecular disulfide to an intermolecular disulfide; dimeric Ilei appears to be involved in neoplastic invasiveness.

  2. overexpression of Fam3c caused reduction of Runx2 (zeige RUNX2 Antikörper) expression at both mRNA and protein levels. Fam3c was localized in the cytoplasm and it was not secreted outside the cell during osteoblast differentiation and therefore, may function intracellularly. Furthermore, Fam3c and TGF-beta1 (zeige TGFB1 Antikörper) were found to regulate each other reciprocally

  3. In obese diabetic mice, FAM3C expression was reduced in the liver, and hepatic FAM3C restoration improved insulin resistance, hyperglycemia, and fatty liver. FAM3C overexpression increased the expression of heat shock factor 1 (HSF1), calmodulin (CaM), and phosphorylated Akt and reduced that of gluconeogenic and lipogenic genes in diabetic mouse livers with the suppression of gluconeogenesis and lipid deposition.

  4. Study used immunohistochemical staining and biochemical fractionation to examine the regional distribution and subcellular localization of ILEI in mouse brains and in autopsy brains of patients with Alzheimer's disease; results suggest that a decline of ILEI expression may cause accumulation of Abeta (zeige APP Antikörper) in the brain and the eventual development of Alzheimer's disease.

  5. TGF-beta (zeige TGFB1 Antikörper) modulates the expression of Dab2 (zeige DAB2 Antikörper) and ILEI mRNA required for epithelial-mesenchymal transdifferentiation by inducing phosphorylation of hnRNP E1 (zeige PCBP1 Antikörper), resulting in its release from a structural, 33-nucleotide BAT (zeige BAAT Antikörper) element in the 3'UTR (zeige UTS2R Antikörper) of Dab2 (zeige DAB2 Antikörper) and ILEI.

  6. FAM3C orthologous protein, may be involved in cell differentiation and proliferation during inner ear embryogenesis

  7. ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors.

  8. ILEI requires cooperation with oncogenic Ras to govern hepatocellular EMT (zeige ITK Antikörper) through mechanisms involving PDGF-R/beta (zeige PDGFRB Antikörper)-catenin (zeige CTNNB1 Antikörper) and PDGF (zeige PDGFA Antikörper)-R/Stat3 (zeige STAT3 Antikörper) signaling.

FAM3C Antigen-Profil

Protein Überblick

This gene is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells.

Genbezeichner und Symbole assoziert mit FAM3C

  • family with sequence similarity 3 member C (fam3c) Antikörper
  • family with sequence similarity 3 member C (FAM3C) Antikörper
  • family with sequence similarity 3, member C (FAM3C) Antikörper
  • family with sequence similarity 3, member C (Fam3c) Antikörper
  • family with sequence similarity 3, member C (fam3c) Antikörper
  • family with sequence similarity 3 member C L homeolog (fam3c.L) Antikörper
  • D6Wsu176e Antikörper
  • Ilei Antikörper
  • wu:fb99h11 Antikörper
  • wu:fi35h03 Antikörper
  • zgc:55444 Antikörper
  • zgc:77090 Antikörper

Bezeichner auf Proteinebene für FAM3C

hypothetical protein LOC549860 , Protein FAM3C , family with sequence similarity 3, member C , protein FAM3C , interleukin-like EMT inducer , predicted osteoblast protein , FAM3C-like protein

GENE ID SPEZIES
549860 Xenopus (Silurana) tropicalis
100221204 Taeniopygia guttata
417758 Gallus gallus
463680 Pan troglodytes
10447 Homo sapiens
612336 Canis lupus familiaris
615690 Bos taurus
27999 Mus musculus
312159 Rattus norvegicus
334205 Danio rerio
443905 Xenopus laevis
Ausgewählte Anbieter für anti-FAM3C (FAM3C) Antikörper
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