anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) Antikörper

EIF4EBP2 encodes a member of the eukaryotic translation initiation factor 4E binding protein family. Zusätzlich bieten wir Ihnen eIF4EBP2 Proteine (21) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
EIF4EBP2 361845  
EIF4EBP2 1979 Q13542
EIF4EBP2 13688 P70445
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Showing 10 out of 90 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>Sample Type:</b> HEK 293 cells (50ug)<br><b>Primary Dilution: </b>1:1000<br><b>Image Submitted by:</b> Veronique Dorval<br>Laval University, Canada .<br><br> 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Kaninchen Unkonjugiert WB EIF4EBP2 Antibody (C-term) (ABIN1881292) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the EIF4EBP2 antibody detected the EIF4EBP2 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Rind (Kuh) Kaninchen Unkonjugiert IHC (p), WB Pancreas, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
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Human Kaninchen Unkonjugiert IHC (p), WB Pancreas, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
517,00 €
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Human Maus Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 13 Days
154,33 €
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Human Huhn Unkonjugiert WB 0.05 mg Anmelden zum Anzeigen 6 bis 8 Tage
472,74 €
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Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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EIF4EBP2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-eIF4EBP2 Antikörper

  1. Human Polyclonal eIF4EBP2 Primary Antibody für WB - ABIN1881292 : Bidinosti, Martineau, Frank, Sonenberg: Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain. in The Journal of biological chemistry 2010 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen eIF4EBP2 Interaktionspartner

Human Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) Interaktionspartner

  1. Results suggest that IGF2BP3 promotes eIF4E-mediated translational activation through the reduction of EIF4E-BP2 via mRNA degradation, leading to enhanced cell proliferation.

  2. molecular dynamics simulations to investigate both the folded and unfolded states of 4E-BP2 under different phosphorylation states of T37 and T46

  3. mTORC1 controls mitochondrial activity and biogenesis by selectively promoting translation of nucleus-encoded mitochondria-related mRNAs via inhibition of the eukaryotic translation initiation factor 4E (eIF4E (zeige EIF4E Antikörper))-binding proteins (4E-BPs).

  4. Data show that the eIF4E (zeige EIF4E Antikörper) binding preference for 4E-BP2 over 4E-BP1 (zeige EIF4EBP1 Antikörper) is based on stacking of Arg63 side chain on Trp73 indole ring of eIF4E (zeige EIF4E Antikörper) and construction of hydrophobic space around the Trp73 indole ring by the Leu59-Leu60 sequence of 4E-BP2.

  5. isoaspartate formation repair modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain

  6. 4E-binding proteins, the suppressors of eukaryotic initiation factor 4E, are down-regulated in cells with acquired or intrinsic resistance to rapamycin.

  7. Data show that H2O2 increased eIF4E (zeige EIF4E Antikörper) and 4E-BP1 (zeige EIF4EBP1 Antikörper) expression and eIF4E (zeige EIF4E Antikörper) phosphorylation, and shifted distribution of 4E-BP1 (zeige EIF4EBP1 Antikörper) phosphorylation. These oxidant-mediated alterations occur in concert with changes in factors known to regulate translation kinetics.

  8. PHAS-II, but not PHAS-III, contributes to the control of protein synthesis by insulin (zeige INS Antikörper)

  9. The C-terminal His74-Glu89 region of 4EBP2 acts as an auxiliary function for the major binding of Y(X)4L -binding motif (Tyr54-Leu60) to eIF4E (zeige EIF4E Antikörper).

  10. 4E-BPs regulate the stress granule localization of eIF4E (zeige EIF4E Antikörper)

Mouse (Murine) Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) Interaktionspartner

  1. data identify SH2B1 (zeige SH2B1 Antikörper) as a major regulator of IRS2 (zeige IRS2 Antikörper) stability, demonstrate a novel feedback mechanism linking mTORC1 signaling with IRS2 (zeige IRS2 Antikörper), and identify 4E-BP2 as a major regulator of proliferation and survival of beta-cells.

  2. Data show that deletion of eukaryotic translation initiation factor 4E-binding protein 1/2 (4E-BP1/2) in erythroid cells rendered them resistant to mammalian target of rapamycin complex 1 (TORC1) inhibition and restored hemoglobin production.

  3. Disruption of genes encoding Eif4ebp1 (zeige EIF4EBP1 Antikörper) and Eif4ebp2 does not alter basal or sepsis-induced changes in skeletal muscle protein synthesis in male or female mice.

  4. 4E-BP1 (zeige EIF4EBP1 Antikörper)/2-null cells express less ATGL (zeige PNPLA2 Antikörper) and accumulate more fat than control cells, while knock down of Egr1 (zeige EGR1 Antikörper) in 4E-BP1 (zeige EIF4EBP1 Antikörper)/2-null cells increases ATGL (zeige PNPLA2 Antikörper) expression and decreases fat storage.

  5. translational control through 4E-BP2 represents a unique mechanism for selective regulation of AMPAR synthesis, synaptic function, and long-term plasticity, important for hippocampal-dependent memory processes.

  6. in the absence of 4E-BP proteins, mTORC1-mediated phosphorylation of p70S6K1 (zeige RPS6KB1 Antikörper) is elevated by a reduction in competition between the two substrates for interaction with raptor (zeige RPTOR Antikörper)

  7. isoaspartate formation repair modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain

  8. Two deamidation sites were mapped to an asparagine-rich sequence unique to 4E-BP2. Deamidated 4E-BP2 exhibits increased binding to the mammalian target of rapamycin (mTOR (zeige FRAP1 Antikörper))-binding protein raptor (zeige RPTOR Antikörper).

  9. These results, together with the fact that 4E-BPs are markedly induced during granulo-monocytic differentiation of myeloid cells in vitro, highlight the pivotal role of 4E-BP1 (zeige EIF4EBP1 Antikörper) and 4E-BP2 in the early phases of myelopoiesis

  10. 4E-BP2 plays a crucial role in proper regulation of the eIF4F (zeige EIF4A2 Antikörper) complex during long-term potentiation and learning and memory in the mouse hippocampus.

eIF4EBP2 (EIF4EBP2) Antigen-Profil

Protein Überblick

This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection.

Genbezeichner und Symbole assoziert mit EIF4EBP2

  • eukaryotic translation initiation factor 4E binding protein 2 (eif4ebp2) Antikörper
  • eukaryotic translation initiation factor 4E binding protein 2 (Eif4ebp2) Antikörper
  • eukaryotic translation initiation factor 4E binding protein 2 (EIF4EBP2) Antikörper
  • eukaryotic initiation factor 4E (TcasGA2_TC012945) Antikörper
  • eukaryotic translation initiation factor 4E (Tb927.6.1870) Antikörper
  • eukaryotic translation initiation factor 4E (LmjF30.0450) Antikörper
  • eukaryotic translation initiation factor 4E binding protein 2 (LOC100342908) Antikörper
  • 4E-BP2 Antikörper
  • 4EBP2 Antikörper
  • 2810011I19Rik Antikörper
  • AA792569 Antikörper
  • BC010348 Antikörper
  • eIF-4E Antikörper
  • EIF4EBP2 Antikörper
  • MGC75579 Antikörper
  • MGC78987 Antikörper
  • PHAS-II Antikörper
  • PHASII Antikörper
  • Tb06.28P18.1010 Antikörper
  • wu:fa55e11 Antikörper
  • wu:fp45e09 Antikörper

Bezeichner auf Proteinebene für EIF4EBP2

eukaryotic translation initiation factor 4E binding protein 2 , eukaryotic translation initiation factor 4E-binding protein 2 , fa55e11 , eukaryotic initiation factor 4E , eukaryotic translation initiation factor 4E , 4E-BP2 , eIF4E-binding protein 2 , phosphorylated, heat and acid stable regulated by insulin protein II , phosphorylated heat- and acid-stable protein regulated by insulin 2

GENE ID SPEZIES
394958 Xenopus (Silurana) tropicalis
361845 Rattus norvegicus
386945 Danio rerio
414476 Xenopus laevis
489027 Canis lupus familiaris
658700 Tribolium castaneum
769479 Gallus gallus
782397 Bos taurus
3657825 Trypanosoma brucei brucei strain 927/4 GUTat10.1
5653570 Leishmania major strain Friedlin
100342908 Oryctolagus cuniculus
1979 Homo sapiens
13688 Mus musculus
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